Liposomal drugs dispersed in hydrogels. Effect of liposome, drug and gel properties on drug release kinetics

Colloids and Surfaces B: Biointerfaces

Volumn 55, Issue 2, 2007, Pages 212-221

  Mourtas, Spyridon ^a   Fotopoulou, Styliani ^a   Duraj, Stela ^a   Sfika, Vassiliki ^a   Tsakiroglou, Christos ^b   Antimisiaris, Sophia G ^a,b  

^a School of Health Sciences   (Greece)

^b INSTITUTE OF COMPUTER SCIENCE   (Greece)

Author keywords

Drug; Hydrogel; Lipid composition; Liposomal gel; Liposome; Release kinetics; Rheology

Indexed keywords

LIPID COMPOSITION; LIPOSOMAL GELS; LIPOSOMES; RELEASE KINETICS;

BIOLOGICAL MEMBRANES; DISPERSIONS; ENZYME IMMOBILIZATION; HYDRATION; HYDROGELS; LIPIDS;

DRUG PRODUCTS;

CALCEIN; CARBOMER; CHOLESTEROL; DISTEAROYLGLYCEROPHOSPHATIDYLCHOLINE; GRISEOFULVIN; LIPOSOME; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BINDING KINETICS; DRUG DIFFUSION; DRUG RECEPTOR BINDING; DRUG RELEASE; FLUORESCENCE ACTIVATED CELL SORTER; GEL; HYDROGEL; LIPOPHILICITY; PHOTOMETRY; PRIORITY JOURNAL; SOLUBILITY; STATISTICAL SIGNIFICANCE;

DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FLUORESCEINS; GRISEOFULVIN; HYDROGELS; KINETICS; LIPOSOMES; PHARMACEUTICAL PREPARATIONS; PHOSPHATIDYLCHOLINES;

EID: 33847030650     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2006.12.005     Document Type: Article

References (22)

1. Lasic D.D. Liposomes-From Physics to Applications (1993), Elsevier Science Publishers, New York
2. Gregoriadis G. Liposomes as Drug Carriers (1988), John Willey, New York
3. Rollan A. Particulate carriers in dermal and transdermal drug delivery: myth or reality. In: Rollan A. (Ed). Pharmaceutical Particulate Carriers. Therapeutic Application (1993), Marcel Dekker, New York 367-421
4. Schreier H., and Bouwstra J. Liposomes and niosomes as topical drug carriers: dermal and transdermal drug delivery. J. Control. Release 30 (1994) 1-5
5. Pavelic Z., Skalko-Basnet N., and Schubert R. Liposomal gels for vaginal drug delivery. Int. J. Pharm. 219 (2001) 139-149
6. Pavelic Z., Skalko-Basnet N., Filipovic-Grcic J., Martinac A., and Jalsenjak I. Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir. J. Control. Release 106 (2005) 34-43
7. Pavelic Z., Skalko-Basnet N., and Jalsenjak I. Characterisation and in vitro evaluation of bioadhesive liposome gels for local therapy of vaginitis. Int. J. Pharm. 301 (2005) 140-148
8. Wang Y., and Lee C.H. Characterization of a female controlled drug delivery system for microbicides. Contraception 66 (2002) 281-287
9. Owen D.H., Peters J.J., Lavine M.L., and Katz D.F. Effect of temperature and pH on contraceptive gel viscosity. Contraception 67 (2003) 57-64
10. Bangham A.D., Standish M.M., and Watkins J.C. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 13 (1965) 238-252
11. Stewart J.C.M. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal. Biochem. 104 (1980) 10-14
12. Kokkona M., Kallinteri P., Fatouros D., and Antimisiaris S.G. Stability of SUV liposomes in the presence of cholate salts and pancreatic lipases: effect of lipid composition. Eur. J. Pharm. Sci. 9 (2000) 245-252
13. Fatouros D., and Antimisiaris S.G. Effect of amphiphilic drugs on the stability and zeta-potential of their liposome formulations: a study with prednisolone, diazepam, and griseofulvin. J. Colloid Interf. Sci. 251 (2002) 271-277
14. Peschka R., Dennehy C., and Szoka F.C. A simple in vitro model to study the release kinetics of liposome encapsulated material. J. Control. Release 56 (1998) 41-51
15. Macosco C.W. Rheology: Principles, Measurements, and Applications (1994), Wiley-VCH, New York
16. Peppas N.A. Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv. 60 (1985) 110-111
17. N. Peppas, J.J. Sahlin, A simple equation for the description of solute release. III. Coupling of diffusion and relaxation (1989).
18. Llabot J.M., Manzo R.H., and Allemandi D.A. Drug release from carbomer: carbomer sodium salt matrices with potential use as mucoadhesive drug delivery system. Int. J. Pharm. 276 (2004) 59-66
19. Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspension. J. Pharm. Sci. 50 (1961) 874-875
20. Glavas-Dodov M., Goracinova K., Mladenovska K., and Fredo-Kumbaradzi E. Release profile of lidocaine HCL from topical liposomal gel formulation. Int. J. Pharm. 242 (2002) 381-384
21. Bochot A., Fattal E., Gulik A., Couarraze G., and Couvreur P. Liposomes dispersed within a thermosensitive gel: a new dosage form for ocular delivery of oligonucleotides. Pharm. Res. 15 (1998) 1364-1369
22. Fattal E., De Rosa G., and Bochot A. Gel and solid matrix systems for the controlled delivery of drug carrier-associated nucleic acids. Int. J. Pharm. 277 (2004) 25-30