Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon

AIDS

Volumn 21, Issue 4, 2007, Pages 527-528

  Torimiro, Judith N ^a   Wolfe, Nathan D ^b   Thomas, Alero ^c   Martin, Maureen P ^d   Mpoudi Ngole, Eitel ^e   Tamoufe, Ubald ^b   Birx, Deborah L ^f   Carrington, Mary ^d   Burke, Donald S ^b   Carr, Jean K ^f  

^a Walter Reed Johns Hopkins Cameroon Program   (Cameroon)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d SAIC FREDERICK INC   (United States)

^e Army Health Research Center   (Cameroon)

^f US Military HIV Research Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; VIRUS LOAD; VIRUS REPLICATION;

CAMEROON; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HIV INFECTIONS; HIV SEROPREVALENCE; HIV-1; HUMANS; RECEPTORS, CCR5; RURAL HEALTH;

EID: 33847030384     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328045c4bd     Document Type: Article

References (8)

1. Ndembi N, Takehisa J, Zekeng L, Kobayashi E, Ngansop C, Songok EM, et al. Genetic diversity of HIV type 1 in rural eastern Cameroon. J Acquir Immune Defic Syndr 2004; 37:1641-1650.
2. Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996; 273:1856-1862.
3. John GC, Bird T, Overbaugh J, Nduati R, Mbori-Ngacha D, Rostron T, et al. CCR5 promoter polymorphisms in a Kenyan perinatal human immunodeficiency virus type 1 cohort: association with increased 2-year maternal mortality. J Infect Dis 2001; 184:89-92.
4. Hladik F, Liu H, Speelmon E, Livingston-Rosanoff D, Sakchalathorn P, Hwangbo Y, et al. Combined effect of CCR5-Δ32 heterozygosity and the CCR5 promoter polymorphism S2459A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission. J Virol 2005; 79:11677-11684.
5. Corbet S, Muller-Trutwin MC, Versmisse P, Delarue S, Ayouba A, Lewis J, et al. Env sequences of simian immunodeficiency viruses from chimpanzees in Cameroon are strongly related to those of human immunodeficiency virus group N from the same geographic area. J Virol 2000; 74:529-534.
6. Wolfe ND, Switzer WM, Carr JK, Bhullar VB, Shanmugam V, Tamoufe U, et al. Naturally acquired simian retrovirus infections in central African hunters. Lancet 2004; 363:932-937.
7. Kristiansen TB, Knudsen TB, Ohlendorff S, Eugen-Olsen. A new multiplex PCR strategy for the simultaneous determination of four genetic polymorphisms affecting HIV-1 disease progression. J Immunol Meth 2001; 252:147-151.
8. Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, et al. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature 2004; 432:769-775.