Detection of Treponema pallidum subsp. pallidum from skin lesions, serum, and cerebrospinal fluid in an infant with congenital syphilis after clindamycin treatment of the mother during pregnancy

Journal of Clinical Microbiology

Volumn 45, Issue 2, 2007, Pages 659-661

  Woznicová, Vladana ^a   Šmajs, David ^a   Wechsler, Dan ^b   Matějková, Petra ^a   Flasarová, Magdalena ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CHLORAMPHENICOL; CIPROFLOXACIN; CLINDAMYCIN; COLISTIN; MEROPENEM; PENICILLIN G;

ANTIBIOTIC SENSITIVITY; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; CONGENITAL SYPHILIS; CULTURE MEDIUM; HUMAN; MALE; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN; NEWBORN DEATH; OSTEOCHONDRITIS; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; SKIN DEFECT; SKIN DISEASE; SYMPTOM; TMPC GENE; TREPONEMA PALLIDUM;

ADULT; ANTI-BACTERIAL AGENTS; CLINDAMYCIN; DNA, BACTERIAL; FEMALE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MALE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; SKIN; SYPHILIS; SYPHILIS, CONGENITAL; TREPONEMA PALLIDUM;

TREPONEMA PALLIDUM SUBSP. PALLIDUM;

EID: 33847027223     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.02209-06     Document Type: Article

References (11)

1. Atkins, D., K. A. Workowski, et al. 2006. Sexually transmitted diseases treatment guidelines, 2006. Morb. Mortal. Wkly. Rep. 55:1-94.
2. Brause, B. D., J. S. Borges, and R. B. Roberts. 1976. Relative efficacy of clindamycin, erythromycin, and penicillin in treatment of Treponema pallidum in skin syphilomas of rabbits. J. Infect. Dis. 134:93-96.
3. Flasarova, M., D. Smajs, P. Matejkova, V. Woznicova, M. Heroldova-Dvorakova, and M. Votava. 2006. Molecular detection and subtyping of Treponema pallidum subsp. pallidum in clinical specimens. Epidemiol. Mikrobiol. Immunol. 55:105-111.
4. Grimprel, E., P. J. Sanchez, G. D. Wendel, J. M. Burstain, G. H. McCracken, J. D. Radolf, and M. V. Norgard. 1991. Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid. J. Clin. Microbiol. 29:1711-1718.
5. Koh, M. T., and C. T. Lim. 1991. Early congenital syphilis: experience with 13 consecutive cases seen at the University Hospital, Kuala Lumpur. Singapore Med. J. 32:230-232.
6. Liu, C. C., W. C. So, C. H. Lin, and T. F. Yeh. 1993. Congenital syphilis: clinical manifestations in premature infants. Scand. J. Infect. Dis. 25:741-745.
7. Michelow, I. C., G. D. Wendel, M. V. Norgard, F. Zeray, N. K. Leos, R. Alsaadi, and P. J. Sanchez. 2002. Central nervous system infection in congenital syphilis. N. Engl. J. Med. 346:1792-1798.
8. Meljanac, N., E. Dippel, and C. C. Zouboulis. 1999. Superimposed primary chancre in a patient with Adamantiades-Behcet's disease. Sex. Transm. Infect. 75:124-125.
9. Sanchez, P. J., G. D. Wendel, Jr., E. Grimprel, M. Goldberg, M. Hall, O. Arencibia-Mireles, J. D. Radolf, and M. V. Norgard. 1993. Evaluation of molecular methodologies and rabbit infectivity testing for the diagnosis of congenital syphilis and neonatal central nervous system invasion by Treponema pallidum. J. Infect. Dis. 167:148-157.
10. Wenhai, L., Z. Jianzhong, and Y. Cao. 2004. Detection of Treponema pallidum in skin lesions of secondary syphilis and characterization of the inflammatory infiltrate. Dermatology 208:94-97.
11. Wu, C. C., C. N. Tsai, W. R. Wong, H. S. Hong, and Y. H. Chuang. 2006. Early congenital syphilis and erythema multiforme-like bullous targetoid lesions in a 1-day-old newborn: detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction. J. Am. Acad. Dermatol. 55:S11-15.