Oxidative damage and oxidative stress in Alzheimer's disease

Research and Practice in Alzheimer's Disease

Volumn 11, Issue , 2006, Pages 110-114

  Keller, Jeffrey N ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Mild cognitive impairment; Oxidative stress; Protein synthesis; Ribosome

Indexed keywords

ANTIOXIDANT; CHAPERONE; HEAT SHOCK PROTEIN; PROTEASOME; PROTEINASE; RNA;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; COGNITIVE DEFECT; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; LIPID OXIDATION; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SENILE PLAQUE;

EID: 33847018793     PISSN: 12848360     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (5)

1. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B (2001) Current concepts in mild cognitive impairment. Arch Neurol 58, 1985-1992
2. Markesbery WR (1999) The role of oxidative stress in Alzheimer's disease. Arch Neurol 1449-1552.
3. Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfield DA, Markesbery WR (2005) Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 64, 1152-1156
4. Williams TL, Lynn BC, Markesbery WR, Lovell MA (2005) Increased levels of 4-hydroxynonenal and acreolin, neurotoxic markers of lipid peroxidation, in the brains of mild cognitive impairment and early Alzheimer's disease. Neurobiol Aging (in press)
5. Ding Q, Markesbery WR, Chen Q, Li F, Keller JN (2005) Ribosome dysfunction is an early event in Alzheimer's disease. J Neurosci 25, 9171-9175