Comprehensive complexity assessment as a key tool for the prediction of in-hospital mortality in heart failure of aged patients admitted to internal medicine wards

Archives of Gerontology and Geriatrics

Volumn 44, Issue SUPPL., 2007, Pages 279-288

  Nardi, R ^a   Fiorino, S ^a   Borioni, D ^a   Agostini, D ^a   D'Anastasio, C ^a   Marchetti, C ^a   Muratori, M ^a  

^a Azienda USL di Bologna   (Italy)

Author keywords

Cognitive dysfunction; Comorbidity; Congestive heart failure (CHF); Disability of elderly; Frailty of the elderly

Indexed keywords

DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; WARFARIN;

AGED; AGED HOSPITAL PATIENT; ARTICLE; CARDIOVASCULAR DISEASE; COGNITIVE DEFECT; COMORBIDITY; CREATININE BLOOD LEVEL; FEMALE; FLUGELMAN INDEX; FRAIL ELDERLY; GERIATRIC PATIENT; HEART FAILURE; HIGH RISK PATIENT; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; SCORING SYSTEM;

AGED; AGED, 80 AND OVER; COGNITION DISORDERS; COMORBIDITY; DISABILITY EVALUATION; FEMALE; HEART FAILURE, CONGESTIVE; HOSPITALIZATION; HUMANS; INTERNAL MEDICINE; MALE; PROSPECTIVE STUDIES;

EID: 33847012172     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2007.01.037     Document Type: Article

References (43)

1. Aaronson K.D., Schwartz J.S., Chen T.M., Wong K.L., Goin J.E., and Mancini D.M. Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation. Circulation 95 (1997) 2660-2667
2. Bennett S.J., and Suave M.J. Cognitive deficits in patients with heart failure: a review of the literature. J. Cardiovasc. Nurs. 18 (2003) 219-242
3. Bouvy M.L., Heerdink E.R., Leufkens H.G., and Hoes A.W. Predicting mortality in patients with heart failure: a pragmatic approach. Heart 89 (2003) 605-609
4. Brophy J.M., Dagenais G.R., McSherry F., Williford W., and Yusuf S. A multivariate model for predicting mortality in patients with heart failure and systolic dysfunction. Am. J. Med. 116 (2004) 300-304
5. Chen M.C., Chang H.W., Cheng C.L., Chen Y.H., and Chai H.T. Risk stratification of in-hospital mortality in patients hospitalized for chronic congestive heart failure secondary to non-ischemic cardiomyopathy. Cardiology 100 (2003) 136-142
6. Clark P.C., and Dunbar S.B. Family partnership intervention: a guide for a family approach to care of patients with heart failure. AACN Clin. Issues 14 (2003) 467-476
7. Criteria Committee, New York Heart Association Inc. 1964. Diseases of the Heart and Blood Vessels. Nomenclature and Criteria for Diagnosis. 6th ed. Little, Brown and Company; Boston, p. 114.
8. Del Sindaco D., Zuccalà G., Pulignano G., and Cocchi A. La valutazione multidimensionale dell'anziano con scompenso cardiaco. Ital. Heart J. 5 Suppl 10 (2004) 26S-36S. (in Italian)
9. Fagerberg B., Ekman I., and Skoog I. Cognitive impairment in elderly patients with chronic heart failure: occurrence and clinical implications. Circulation 100 Suppl. 18 (1999) I-253 (abstract only)
10. Flugelman M.Y., Ben David Y., Harats N., and Eliakim M. A simple prognostic index for hospitalized geriatric patients. A prospective study of 70 patients. Gerontology 32 (1986) 272-276
11. Folstein M.F., Folstein S.E., and McHugh P.R. Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12 (1975) 189-198
12. Fried L.P., Ferrucci L., Darer J., Williamson J.D., and Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J. Gerontol. A. Biol. Sci. Med. Sci. 59 (2004) M255-M263
13. Gradman A., Deedwania P., Cody R., Massie B., Packer M., Pitt B., and Goldstein S. Predictors of total mortality and sudden death in mild to moderate heart failure. J. Am. Coll. Cardiol. 14 (1989) 564-570
14. Gussekloo J., Westendorp R.G.J., Remarque E.J., Lagaay A.M., Hereen T.J., and Knook D.L. Impact of mild cognitive impairment on survival in very elderly people: cohort study. Br. Med. J. 315 (1997) 1053-1054
15. Jones A.M., O'Connell J.E., and Gray C.S. Living and dying with congestive heart failure: addressing the needs of older congestive heart failure patients. Age Ageing 32 (2003) 566-568
16. Katz S. Assessing self-maintenance: Activities of daily living, mobility and instrumental activities of daily living. J. Am. Geriatr. Soc. 31 (1983) 721-726
17. Kearney M.T., Nolan J., Lee A.J., Brooksby P.W., Prescott R., Shah A.M., Zaman A.G., Eckberg D.L., Lindsay H.S., Batin P.D., Andrews R., and Fox K.A. A prognostic index to predict long-term mortality in patients with mild to moderate chronic heart failure stabilized on angiotensin converting enzyme inhibitors. Eur. J. Heart Failure 5 (2003) 489-497
18. Linn B.S., Linn M.W., and Gurel L. Cumulative illness rating scale. J. Am. Geriatr. Soc. 16 (1968) 622-626
19. Masoudi F.A., Baillie C.A., Wang Y.W., David Bradford W.D., Steiner J.F., Havranek E.P., Foody J.M., and Krumholz H.M. The complexity and cost of drug regimens of older patients hospitalized with heart failure in the United States, 1998-2001. Arch. Intern. Med. 165 (2005) 2069-2076
20. McAlister F.A., Ezekowitz J., Tonelli M., and Armstrong P.W. Renal insufficiency and heart failure prognostic and therapeutic implications from a prospective cohort study. Circulation 109 (2004) 1004-1009
21. McKee P.A., Castelli W.P., McNamara P.M., and Kannel W.B. The natural history of congestive heart failure: the Framingham study. N. Engl. J. Med. 285 (1971) 1441-1446
22. McMurray J.J., Young J.B., Dunlap M.E., Granger C.B., Hainer J., Michelson E.L., Earle S., Olofsson B., Ostergren J., Yusuf S., Swedberg K., Pfeffer M.A., and The CHARM Investigators. Relationship of dose of background angiotensin-converting enzyme inhibitor to the benefits of candesartan in the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM)-Added trial. Am. Heart J. 151 (2006) 985-991
23. Miller M.D., Paradis C.F., Houck P.R., Mazumdar S., Stack J.A., Rifai A.H., Mulsant B., and Reynolds C.F.3rd. Rating chronic medical illness burden in gero-psychiatric practice and research: application of the cumulative illness rating scale. Psychiatry Res. 41 (1992) 237-248
24. Murberg T.A., and Bru E. Social relationships and mortality in patients with congestive heart failure. J. Psychosom. Res. 51 (2001) 521-527
25. Philbin E.F., William G., Jenkins P.L., and DiSalvo T.G. Socioeconomic status as an independent risk factor for hospital readmission for heart failure. Am. J. Cardiol. 87 (2001) 1367-1371
26. Pocock S.J., Wang D., Pfeffer M.A., Yusuf S., McMurray J.J., Swedberg K.B., Ostergren J., Michelson E.L., Pieper K.S., and Granger C.B. Predictors of mortality and morbidity in patients with chronic heart failure. Eur. Heart J. 27 (2006) 65-75
27. Radford, M.J., Arnold, J.M., Bennett, S.J., Cinguegrani, M.P., Cleland, J.G., Havranek, E.P., Heidenreich, P.A., Rutherford, J.D., Spertus, J.A., Stevenson, L.W., Goff. D.C., Graver, F.L., Malenka, D.J., Peterson, J.D. and Redberg, R. (Writing Committee to Develop Heart Failure Clinical Data Standards) (2005): ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with chronic heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards. Circulation, 112, 1888-1916.
28. Rengo F., Acanfora D., Trojano L., Scognamiglio P., Ciaburri F., Ceriello A., Bollella O.F., Lanzillo T., and Papa A. Congestive heart failure and cognitive impairment in the elderly. Arch. Gerontol. Geriatr. 20 (1995) 63-68
29. Rich M.W. Heart failure in the 21st century: a cardiogeriatric syndrome. J. Gerontol. A. Biol. Sci. Med. Sci. 56 (2001) M88-M96
30. Riegel B., Bennett J.A., Davis A., Carlson B., Montague J., Robin H., and Glaser D. Cognitive impairment in heart failure: issues of measurement and etiology. Am. J. Crit. Care 6 (2002) 520-528
31. Rozzini R., Franzoni S., Frisoni G., and Trabucchi M. Cognitive impairment and survival in very elderly people. Decreased survival with cognitive impairment seems not be related to comorbidity. Br. Med. J. 316 (1998) 1674
32. Rozzini R., Sabatini T., Barbisoni P., Bellelli G., and Trabucchi M. Dementia is a major predictor of death among the Italian elderly. Neurology 54 (2000) 1014
33. Sangha S.S., Uber P.A., Park M.H., Scott R.L., and Mehra M.R. Difficult cases in heart failure: the challenge of neurocognitive dysfunction in severe heart failure. Cong. Heart Failure 4 (2002) 232-234
34. Taylor J. Chronic heart failure and cognitive impairment: co-existence of conditions or true association?. Eur. J. Heart Fail. 4 (2002) 7-9
35. Tinetti M.E., Williams T.F., and Mayewski R. Fall risk index for elderly patients based on number of chronic disabilities. Am. J. Med. 80 (1986) 429-434
36. Trojano L., Antonelli-lncalzi R., Acanfora D., Picone C., Mecocci P., Rengo F., and CHF Italian Study Investigators. Cognitive impairment: a key feature of congestive heart failure in the elderly. J. Neural. 250 (2003) 1456-1463
37. Varadarajan P., and Pai R.G. Prognosis of congestive heart failure in patients with normal versus reduced ejection fractions: results from a cohort of 2,258 hospitalized patients. J. Card. Fail. 9 (2003) 107-112
38. Watson R.D., Gibbs C.R., and Lip G.Y. ABC of heart failure. Clinical features and complications. Br. Med. J. 320 (2000) 236-239
39. Zuccala G., Cattel C., Manes-Gravina E., Di Niro M.G., Cocchi A., and Bernabei R. Left ventricular dysfunction: a clue to cognitive impairment in older patients with heart failure. J. Neural. Neurosurg. Psychiatry 63 (1997) 509-512
40. Zuccalà G., Onder G., Pedone C., Cocchi A., Carosella L., Cattel C., Carbonin P.U., Bernabei R., and On behalf of the GIFA (SIGG-ONLUS) Investigators. Cognitive dysfunction as a major determinant of disability in patients with heart failure: results from a multicentre survey. J. Neural. Neurosurg. Psychiatry 70 (2001) 109-112
41. Zuccalà G., Pedone C., Cesari M., Onder G., Pahor M., Marzetti E., Lo Monaco M.R., Cocchi A., Carbonin P., and Bernabei R. The effect of cognitive impairment on mortality among hospitalized patients with heart failure. Am. J. Med. 115 (2003) 97-103
42. Zuccàla G., Onder G., Marzetti E., Monaco M.R., Cesari M., Cocchi A., Carbonin P., Bernabei R., and GIFA Study Group. Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure. Eur. Heart J. 26 (2005) 226-233
43. Zuccalà G., Marzetti E., Cesari M., Lo Monaco M.R., Antonica L., Cocchi A., Carbonin P., and Bernabei R. Correlates of cognitive impairment among patients with heart failure: Results of a multicenter survey. Am. J. Med. 118 (2005) 496-502