Understanding oligomerization in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: An in silico approach and evidence for an active protein

Journal of Biotechnology

Volumn 129, Issue 1, 2007, Pages 131-139

  Hoffmann, Frank ^a   Sotriffer, Christoph ^a   Evers, Andreas ^a   Xiong, Guangming ^b   Maser, Edmund ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

3 HSD CR; Dimerization; MD simulation; SDR

Indexed keywords

BACTERIA; BIOREMEDIATION; ENZYME KINETICS; MOLECULAR DYNAMICS; PROTEINS; REDOX REACTIONS; TOXIC MATERIALS;

CARBONYL REDUCTASE; COMAMONAS TESTOSTERONI; HYDROXYSTEROID DEHYDROGENASE; STEROIDS; STREPTOMYCES HYDROGENANS;

OLIGOMERIZATION;

3ALPHA HYDROXYSTEROID DEHYDROGENASE; CARBONYL REDUCTASE; ENZYME; PEPTIDE; TETRAMER; 3 ALPHA HYDROXYSTEROID DEHYDROGENASE (B SPECIFIC); AMINO ACID; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CHEMICAL STRUCTURE; COMAMONAS TESTOSTERONI; COMPUTER MODEL; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTAGENESIS; MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; SIMULATION; AMINO ACID SEQUENCE; BIOLOGY; CATALYSIS; CHEMISTRY; COMPUTER SIMULATION; ENZYMOLOGY; GENETICS; METHODOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY;

COMAMONAS TESTOSTERONI; STREPTOMYCES EXFOLIATUS;

3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC); AMINO ACID SEQUENCE; AMINO ACIDS; CATALYSIS; CLONING, MOLECULAR; COMAMONAS TESTOSTERONI; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 33847011071     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2006.11.024     Document Type: Article

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