Cytoprotective effect of Podophyllum hexandrum against gamma radiation is mediated via hemopoietic system stimulation and up-regulation of heme-oxygenase-1 and the prosurvival multidomain protein Bcl-2

Integrative Cancer Therapies

Volumn 6, Issue 1, 2007, Pages 54-65

  Rajesh, Arora ^a   Sagar, R ^a,b   Singh, S ^a   Kumar, R ^a   Sharma, A K ^a   Prasad, J ^a   Gupta, M ^a   Sharma, R K ^a   Puri, S C ^c   Krishna, B ^d   Siddiqui, M S ^e   Lahiri, S S ^a   Tripathi, R P ^a   Qazi, G N ^c  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^b UNIVERSITY OF DELHI   (India)

^c CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^d MAULANA AZAD MEDICAL COLLEGE   (India)

^e HAMDARD UNIVERSITY   (India)

Author keywords

Heme oxygenase; Hemopoietic system; Himalayan Mayapple; Lethal ionizing radiation; Podophyllum hexandrum; Radioprotection

Indexed keywords

HEME OXYGENASE 1; HEMOGLOBIN; PLANT EXTRACT; PODOPHYLLUM HEXANDRUM EXTRACT; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; GAMMA RADIATION; HEMATOPOIETIC SYSTEM; LEUKOCYTE COUNT; MALE; MOUSE; NONHUMAN; PODOPHYLLUM HEXANDRUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RHIZOME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAMMA RAYS; HEMATOPOIETIC SYSTEM; HEME OXYGENASE-1; HEMOGLOBINS; LEUKOCYTES; MALE; MICE; MICE, INBRED STRAINS; PLANT EXTRACTS; PODOPHYLLUM; PROTO-ONCOGENE PROTEINS; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; UP-REGULATION;

EID: 33847006940     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735406298303     Document Type: Article

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