Microcytosis, iron deficiency and thalassaemia in a multi-ethnic community: A pilot study

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 67, Issue 1, 2007, Pages 87-96

  Wonke, B ^a   Modell, M ^b   Marlow, T ^a   Khan, M ^b   Modell, B ^b,c  

^a WHITTINGTON HOSPITAL   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ethnic group; Ferritin; Iron deficiency; Microcytosis; Screening policy; Thalassaemia

Indexed keywords

EDETATE DISODIUM; FERRITIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD CELL COUNT; BLOOD SAMPLING; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; ETHNIC GROUP; ETHNICITY; EUROPE; FEMALE; FERRITIN BLOOD LEVEL; GENERAL HOSPITAL; GENERAL PRACTITIONER; HEMOGLOBINOPATHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IRON DEFICIENCY; MAJOR CLINICAL STUDY; MALE; MATERNAL CARE; MICROCYTOSIS; PILOT STUDY; PREVALENCE; PRIMARY HEALTH CARE; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOM SAMPLE; SCREENING; THALASSEMIA;

EID: 33847004059     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.1080/00365510601046474     Document Type: Article

References (15)

1. Weatherall DJ, Clegg JB. The thalassaemia syndromes. 4th edn. Oxford, London, Edinburgh, Boston, Melbourne: Blackwell Scientific Publications; 2001.
2. Waterstone M, Bewley S, Wolfe C. Incidence and predictors of severe obstetric morbidity: case-control study. Br Med J 2001;322:1089-93.
3. The NHS Plan. A plan for investment, a plan for reform. Her Majesty's Stationery Office; 2000. p. 109.
4. Guideline. The laboratory diagnosis of haemoglobinopathies. Br J Haematol 1998;101:783-92 (Prepared by a Working Party of the General Haematology Task Force of the British Committee for Standards in Haematology.).
5. Serjeant GR. Sickle cell disease. 3rd edn. Oxford, New York, Tokyo: Oxford University Press; 2001.
6. Modell B, Berdoukas V. The clinical approach to thalassaemia. New York and London: Grune and Stratton; 1984.
7. Higgs DR, Vickers MA, Wilkie AOM, Pretorius IM, Jarman AP, Weatherall DJ. A review of the molecular genetics of the human alpha globin gene cluster. Blood 1989;73:1081-104.
8. Leurquin P, Van-Casteren V, De-Maeseneer J. Use of blood tests in general practice: a collaborative study in eight European countries. Eurosentinel Study Group. Br J General Practice 1995;45:21-5.
9. Cook JD. Iron-deficiency anaemia. Baillière's Clin Haematol 1994;7:787-804.
10. Hoffbrand AV, Pettit JE. Essential haematology. 3rd edn. Oxford: Blackwell Science; 1993. p. 24.
11. Lipschitz DA, Cook JD, Finch CA. A clinical evaluation of serum ferritin as an index of iron stores. N Engl J Med 1974;290:1213-16.
12. Hickman M, Modell B, Greengross P, Chapman C, Layton M, Gill M, et al. Mapping the prevalence of sickle cell and b thalassaemia in England: recommended rates for local service planning. Br J Haematol 1999;104:860-7.
13. Tillyer ML, Varawalla NY, Tillyer CR, Sandhu P, Modell B. Thalassaemias, abnormal haemoglobins and iron deficiency in a British Asian population. Clin Lab Haematol 1993;15:157-64.
14. Modell M, Wonke B, Anionwu E, Khan M, See Tai S, et al. A multidisciplinary approach for improving services in primary care: the example of screening for haemoglobin disorders. Br Med J 1998;317:788-91.
15. Information materials for carriers and couples at risk of haemoglobin disorders available at APoGI (Accessible Publishing of Genetic Information) www.chime.ucl.ac.uk/APoGI/.