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Volumn 5, Issue 12, 2006, Pages 1714-1720

Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes

Author keywords

Adenocarcinoma; Apoptosis; Bcl 2; Colorectal; Regenerating gene; Resistance; Tumorigenesis

Indexed keywords

APC PROTEIN; PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN REG; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 33847000899     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.12.3469     Document Type: Article
Times cited : (29)

References (29)
  • 2
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 3
    • 0035135578 scopus 로고    scopus 로고
    • Adjuvant treatment of colorectal cancer at the turn of the century: European and US perspectives
    • Wils J, O'Dwyer P, Labianca R. Adjuvant treatment of colorectal cancer at the turn of the century: European and US perspectives. Ann Oncol 2001; 12:13-22.
    • (2001) Ann Oncol , vol.12 , pp. 13-22
    • Wils, J.1    O'Dwyer, P.2    Labianca, R.3
  • 4
    • 0034953632 scopus 로고    scopus 로고
    • Apoptosis-regulating proteins as targets for drug discovery
    • Reed JC. Apoptosis-regulating proteins as targets for drug discovery. Trends Mol Med 2001; 7:314-9.
    • (2001) Trends Mol Med , vol.7 , pp. 314-319
    • Reed, J.C.1
  • 5
    • 0032145473 scopus 로고    scopus 로고
    • Bcl-2-mediated inhibition of apoptosis prevents immunogenicity and restores tumorigenicity of spontaneously regressive tumors
    • Bonnotte B, Favre N, Moutet M, Fromentin A, Solary E, Martin M, Martin F. Bcl-2-mediated inhibition of apoptosis prevents immunogenicity and restores tumorigenicity of spontaneously regressive tumors. J Immunol 1998; 161:1433-8.
    • (1998) J Immunol , vol.161 , pp. 1433-1438
    • Bonnotte, B.1    Favre, N.2    Moutet, M.3    Fromentin, A.4    Solary, E.5    Martin, M.6    Martin, F.7
  • 6
    • 0036533524 scopus 로고    scopus 로고
    • Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status
    • Violette S, Poulain L, Dussaulx E, Pepin D, Faussat AM, Chambaz J, Lacorte JM, Staedel C, Lesuffleur T. Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status. Int J Cancer 2002; 98:498-504.
    • (2002) Int J Cancer , vol.98 , pp. 498-504
    • Violette, S.1    Poulain, L.2    Dussaulx, E.3    Pepin, D.4    Faussat, A.M.5    Chambaz, J.6    Lacorte, J.M.7    Staedel, C.8    Lesuffleur, T.9
  • 7
    • 0028060113 scopus 로고
    • Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer
    • Lasserre C, Simon MT, Ishikawa H, Diriong S, Nguyen VC, Christa L, Vernier P, Brechot C. Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer. Eur J Biochem 1994; 224:29-38.
    • (1994) Eur J Biochem , vol.224 , pp. 29-38
    • Lasserre, C.1    Simon, M.T.2    Ishikawa, H.3    Diriong, S.4    Nguyen, V.C.5    Christa, L.6    Vernier, P.7    Brechot, C.8
  • 8
    • 0028927383 scopus 로고
    • Age-related changes in peptide-23/pancreatitis-associated protein and pancreatic stone protein/reg gene expression in the rat and regulation by growth hormone-releasing hormone
    • Chakraborty C, Katsumata N, Myal Y, Schroedter IC, Brazeau P, Murphy LJ, Shiu RP, Friesen HG. Age-related changes in peptide-23/pancreatitis-associated protein and pancreatic stone protein/reg gene expression in the rat and regulation by growth hormone-releasing hormone. Endocrinology 1995; 136:1843-9.
    • (1995) Endocrinology , vol.136 , pp. 1843-1849
    • Chakraborty, C.1    Katsumata, N.2    Myal, Y.3    Schroedter, I.C.4    Brazeau, P.5    Murphy, L.J.6    Shiu, R.P.7    Friesen, H.G.8
  • 10
    • 0035897122 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV
    • Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK. Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV. Biochim Biophys Acta 2001; 1518:287-93.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 287-293
    • Hartupee, J.C.1    Zhang, H.2    Bonaldo, M.F.3    Soares, M.B.4    Dieckgraefe, B.K.5
  • 11
    • 0034603809 scopus 로고    scopus 로고
    • Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region
    • Abe M, Nata K, Akiyama T, Shervani NJ, Kobayashi S, Tomioka-Kumagai T, Ito S, Takasawa S, Okamoto H. Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region. Gene 2000; 246:111-22.
    • (2000) Gene , vol.246 , pp. 111-122
    • Abe, M.1    Nata, K.2    Akiyama, T.3    Shervani, N.J.4    Kobayashi, S.5    Tomioka-Kumagai, T.6    Ito, S.7    Takasawa, S.8    Okamoto, H.9
  • 12
    • 0029944843 scopus 로고    scopus 로고
    • Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia
    • Zenilman ME, Perfetti R, Swinson K, Magnuson T, Shuldiner AR. Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia. Surgery 1996; 119:576-84.
    • (1996) Surgery , vol.119 , pp. 576-584
    • Zenilman, M.E.1    Perfetti, R.2    Swinson, K.3    Magnuson, T.4    Shuldiner, A.R.5
  • 16
    • 0037341953 scopus 로고    scopus 로고
    • Overexpression of pancreatitis-associated protein (PAP) in human pancreatic ductal adenocarcinoma
    • Xie MJ, Motoo Y, Iovanna JL, Su SB, Ohtsubo K, Matsubara F, Sawabu N. Overexpression of pancreatitis-associated protein (PAP) in human pancreatic ductal adenocarcinoma. Dig Dis Sci 2003; 48:459-64.
    • (2003) Dig Dis Sci , vol.48 , pp. 459-464
    • Xie, M.J.1    Motoo, Y.2    Iovanna, J.L.3    Su, S.B.4    Ohtsubo, K.5    Matsubara, F.6    Sawabu, N.7
  • 17
    • 26044463766 scopus 로고    scopus 로고
    • Expression and localization of Reg IV in human neoplastic and nonneoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma
    • Oue N, Mitani Y, Aung PP, Sakakura C, Takeshima Y, Kaneko M, Noguchi T, Nakayama H, Yasui W. Expression and localization of Reg IV in human neoplastic and nonneoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. J Pathol 2005; 207:185-98.
    • (2005) J Pathol , vol.207 , pp. 185-198
    • Oue, N.1    Mitani, Y.2    Aung, P.P.3    Sakakura, C.4    Takeshima, Y.5    Kaneko, M.6    Noguchi, T.7    Nakayama, H.8    Yasui, W.9
  • 20
    • 16844362558 scopus 로고    scopus 로고
    • Gu Z, Rubin MA, Yang Y, Deprimo SE, Zhao H, Horvath S, Brooks JD, Loda M, Reiter RE. Reg IV: A promising marker of hormone refractory metastatic prostate cancer. Clin Cancer Res 2005; 11:2237-43.
    • Gu Z, Rubin MA, Yang Y, Deprimo SE, Zhao H, Horvath S, Brooks JD, Loda M, Reiter RE. Reg IV: A promising marker of hormone refractory metastatic prostate cancer. Clin Cancer Res 2005; 11:2237-43.
  • 21
    • 30044442435 scopus 로고    scopus 로고
    • Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas
    • Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 2006; 130:137-49.
    • (2006) Gastroenterology , vol.130 , pp. 137-149
    • Bishnupuri, K.S.1    Luo, Q.2    Murmu, N.3    Houchen, C.W.4    Anant, S.5    Dieckgraefe, B.K.6
  • 22
    • 0142245698 scopus 로고    scopus 로고
    • Expression of a novel regenerating gene product, Reg IV, by high density fermentation in Pichia pastoris: Production, purification, and characterization
    • Li A, Crimmins DL, Luo Q, Hartupee J, Landt Y, Ladenson JH, Wilson D, Anant S, Dieckgraefe BK. Expression of a novel regenerating gene product, Reg IV, by high density fermentation in Pichia pastoris: Production, purification, and characterization. Protein Expr Purif 2003; 31:197-206.
    • (2003) Protein Expr Purif , vol.31 , pp. 197-206
    • Li, A.1    Crimmins, D.L.2    Luo, Q.3    Hartupee, J.4    Landt, Y.5    Ladenson, J.H.6    Wilson, D.7    Anant, S.8    Dieckgraefe, B.K.9
  • 23
    • 0842313184 scopus 로고    scopus 로고
    • Detection of murine intestinal adenomas using targeted molecular autofluorescence
    • Banerjee B, Henderson JO, Chaney TC, Davidson NO. Detection of murine intestinal adenomas using targeted molecular autofluorescence. Dig Dis Sci 2004; 49:54-9.
    • (2004) Dig Dis Sci , vol.49 , pp. 54-59
    • Banerjee, B.1    Henderson, J.O.2    Chaney, T.C.3    Davidson, N.O.4
  • 24
    • 0033094311 scopus 로고    scopus 로고
    • Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas
    • Ogura E, Senzaki H, Yamamoto D, Yoshida R, Takada H, Hioki K, Tsubura A. Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas. Oncol Rep 1999; 6:365-9.
    • (1999) Oncol Rep , vol.6 , pp. 365-369
    • Ogura, E.1    Senzaki, H.2    Yamamoto, D.3    Yoshida, R.4    Takada, H.5    Hioki, K.6    Tsubura, A.7
  • 25
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman JA. Apoptosis induced by anticancer drugs. Cancer Metastasis Rev 1992; 11:121-39.
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 26
    • 0028329172 scopus 로고
    • Apoptosis: Its significance in cancer and cancer therapy
    • Kerr JF, Winterford CM, Harmon BV. Apoptosis: Its significance in cancer and cancer therapy. Cancer 1994; 73:2013-26.
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Winterford, C.M.2    Harmon, B.V.3
  • 27
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. Mechanisms and genes of cellular suicide. Science 1995; 267:1445-9.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 28
    • 0035038022 scopus 로고    scopus 로고
    • Harada K, Zen Y, Kanemori Y, Chen TC, Chen MF, Yeh TS, Jan YY, Masuda S, Nimura Y, Takasawa S, Okamoto H, Nakanuma Y. Human REG I gene is up-regulated in intrahepatic cholangiocarcinoma and its precursor lesions. Hepatology 2001; 33:1036-42.
    • Harada K, Zen Y, Kanemori Y, Chen TC, Chen MF, Yeh TS, Jan YY, Masuda S, Nimura Y, Takasawa S, Okamoto H, Nakanuma Y. Human REG I gene is up-regulated in intrahepatic cholangiocarcinoma and its precursor lesions. Hepatology 2001; 33:1036-42.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.