-
1
-
-
0043028534
-
A cell-based approach for the early assessment of phospholipidogenic potential in pharmaceutical research and drug development
-
Casartelli, A., Bonato, M., Cristofori, P., Crivellente, F., Dal Negro, G., Masotto, I., Mutinelli, C., Valko, K., and Bonfante, V. 2003. A cell-based approach for the early assessment of phospholipidogenic potential in pharmaceutical research and drug development. Cell Biol. Toxicol. 19:161-176.
-
(2003)
Cell Biol. Toxicol
, vol.19
, pp. 161-176
-
-
Casartelli, A.1
Bonato, M.2
Cristofori, P.3
Crivellente, F.4
Dal Negro, G.5
Masotto, I.6
Mutinelli, C.7
Valko, K.8
Bonfante, V.9
-
2
-
-
0021207278
-
Early effects of gentamicin, tobramycin and amikacin on the human kidney
-
De Broe, M. E., Paulus, G. J., Verpooten, G. A., Roels, F., Buyssens, N., Wedeen, R., and Tulkens, P. 1984. Early effects of gentamicin, tobramycin and amikacin on the human kidney. Kidney Int. 25:643-652.
-
(1984)
Kidney Int
, vol.25
, pp. 643-652
-
-
De Broe, M.E.1
Paulus, G.J.2
Verpooten, G.A.3
Roels, F.4
Buyssens, N.5
Wedeen, R.6
Tulkens, P.7
-
3
-
-
0032546350
-
Cellular uptake of stearic, oleic, linoleic, and linolenic acids and their effects on synthesis and secretion of lipids in Hep-G2 cells
-
Dokko, R. C., Cho, B. H., and Chung, B. H. 1998. Cellular uptake of stearic, oleic, linoleic, and linolenic acids and their effects on synthesis and secretion of lipids in Hep-G2 cells. Int. J. Biochem. Cell. Biol. 30:65-76.
-
(1998)
Int. J. Biochem. Cell. Biol
, vol.30
, pp. 65-76
-
-
Dokko, R.C.1
Cho, B.H.2
Chung, B.H.3
-
4
-
-
0020629781
-
Corneal lipidosis in rats treated with amphiphilic cationic drugs
-
Drenckhahn, D., Jacobi, B., and Lullmann-Rauch, R. 1983. Corneal lipidosis in rats treated with amphiphilic cationic drugs. Arzneimittelforschung 33:827-831.
-
(1983)
Arzneimittelforschung
, vol.33
, pp. 827-831
-
-
Drenckhahn, D.1
Jacobi, B.2
Lullmann-Rauch, R.3
-
5
-
-
0020929522
-
Preparation of primary cultures of rat hepatocytes suitable for in vitro toxicity testing
-
Elliget, K. A., and Kolaja, G. J. 1983. Preparation of primary cultures of rat hepatocytes suitable for in vitro toxicity testing. J. Tissue Culture Methods 8:1-6.
-
(1983)
J. Tissue Culture Methods
, vol.8
, pp. 1-6
-
-
Elliget, K.A.1
Kolaja, G.J.2
-
6
-
-
0020075408
-
Aminoglycosides induce a phospholipidosis in renal cortex of the rat: An early manifestation of nephrotoxicity
-
Feldman, S., Wang, M.-Y., and Kaloyanides, G. J. 1982. Aminoglycosides induce a phospholipidosis in renal cortex of the rat: an early manifestation of nephrotoxicity. J. Pharmacol. Exp. Ther. 220:514-520.
-
(1982)
J. Pharmacol. Exp. Ther
, vol.220
, pp. 514-520
-
-
Feldman, S.1
Wang, M.-Y.2
Kaloyanides, G.J.3
-
7
-
-
0022005273
-
Comparison of hydroxychloroquine and chloroquine use and the development of retinal toxicity
-
Finbloom, D. S., Silver, K., Newsome, D. A., and Gunkel, R. 1985. Comparison of hydroxychloroquine and chloroquine use and the development of retinal toxicity. J. Rheumatol. 12:692-694.
-
(1985)
J. Rheumatol
, vol.12
, pp. 692-694
-
-
Finbloom, D.S.1
Silver, K.2
Newsome, D.A.3
Gunkel, R.4
-
8
-
-
0029002049
-
Fluoxetine hydrochloride (Prozac)-induced pulmonary disease
-
Gonzalez-Rothi, R. J., Zander, D. S., and Ros, P. R. 1995. Fluoxetine hydrochloride (Prozac)-induced pulmonary disease. Chest 107:1763-1765.
-
(1995)
Chest
, vol.107
, pp. 1763-1765
-
-
Gonzalez-Rothi, R.J.1
Zander, D.S.2
Ros, P.R.3
-
9
-
-
0035894049
-
Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes
-
Gum, R. J., Hickman, D., Fagerland, J. A., Heindel, M. A., Gagne, G. D., Schmidt, J. M., Michaelides, M. R., Davidsen, S. K., and Ulrich, R. G. 2001. Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes. Biochem. Pharmacol. 62:1661-1673.
-
(2001)
Biochem. Pharmacol
, vol.62
, pp. 1661-1673
-
-
Gum, R.J.1
Hickman, D.2
Fagerland, J.A.3
Heindel, M.A.4
Gagne, G.D.5
Schmidt, J.M.6
Michaelides, M.R.7
Davidsen, S.K.8
Ulrich, R.G.9
-
10
-
-
0025217562
-
Effects of long-term chloroquine exposure on the phospholipids metabolism in retina and pigment epithelium of the mouse
-
Hallberg, A., Naeser, P., and Andersson, A. 1990. Effects of long-term chloroquine exposure on the phospholipids metabolism in retina and pigment epithelium of the mouse. Acta Ophthalmol 68:125-130.
-
(1990)
Acta Ophthalmol
, vol.68
, pp. 125-130
-
-
Hallberg, A.1
Naeser, P.2
Andersson, A.3
-
11
-
-
26844569563
-
In vitro and in vivo ultrastructural changes induced by macrolide antibiotic LY281389
-
Horn, J. W., Jensen, C. B., White, S. L., Laska, D. A., Novilla, M. N., Giera, D. D., and Hoover, D. M. 1996. In vitro and in vivo ultrastructural changes induced by macrolide antibiotic LY281389. Fundam. Appl. Toxicol. 32:205-216.
-
(1996)
Fundam. Appl. Toxicol
, vol.32
, pp. 205-216
-
-
Horn, J.W.1
Jensen, C.B.2
White, S.L.3
Laska, D.A.4
Novilla, M.N.5
Giera, D.D.6
Hoover, D.M.7
-
12
-
-
0019432284
-
Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C
-
Hostetler, K. Y., and Matsuzawa, Y. 1981. Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C. Biochem. Pharmacol. 30:1121-1126.
-
(1981)
Biochem. Pharmacol
, vol.30
, pp. 1121-1126
-
-
Hostetler, K.Y.1
Matsuzawa, Y.2
-
13
-
-
0021288057
-
Pulmonary and generalized lysosomal storage induced by amphiphilic drugs
-
Hruban, Z. 1984. Pulmonary and generalized lysosomal storage induced by amphiphilic drugs. Environ. Health Perspect. 55:53-76.
-
(1984)
Environ. Health Perspect
, vol.55
, pp. 53-76
-
-
Hruban, Z.1
-
14
-
-
0023719056
-
Types of interaction of amphiphilic drugs with phospholipid vesicles
-
Joshi, U. M., Rao, P., Kodavanti, S., Coudert, B., Dwyer, T. M., and Mehendale, H. M. 1988. Types of interaction of amphiphilic drugs with phospholipid vesicles. J. Pharmacol. Exp. Ther. 246:150-157.
-
(1988)
J. Pharmacol. Exp. Ther
, vol.246
, pp. 150-157
-
-
Joshi, U.M.1
Rao, P.2
Kodavanti, S.3
Coudert, B.4
Dwyer, T.M.5
Mehendale, H.M.6
-
15
-
-
0021971554
-
Gentamicin or chlorphentermine induction of phospholipidosis in the developing organism: Role of tissue and species in manifestation of toxicity
-
Kacew, S. 1985. Gentamicin or chlorphentermine induction of phospholipidosis in the developing organism: role of tissue and species in manifestation of toxicity. J. Pharmacol. Exp. Ther. 232:239-243.
-
(1985)
J. Pharmacol. Exp. Ther
, vol.232
, pp. 239-243
-
-
Kacew, S.1
-
17
-
-
0025654627
-
In vivo toxicity and pulmonary effects of promazine and chlorpromazine in rats
-
Kodavanti, U. P., Lockard, V. G., and Mehendale, H. M. 1990. In vivo toxicity and pulmonary effects of promazine and chlorpromazine in rats. J. Biochem. Toxicol. 5:245-251.
-
(1990)
J. Biochem. Toxicol
, vol.5
, pp. 245-251
-
-
Kodavanti, U.P.1
Lockard, V.G.2
Mehendale, H.M.3
-
18
-
-
0023022478
-
Binding of propranolol and gentamicin to small unilamellar phospholipids vesicles. Contribution of ionic and hydrophobic forces
-
Kubo, M., Gardner, M. F., and Hostetler, K. Y. 1986. Binding of propranolol and gentamicin to small unilamellar phospholipids vesicles. Contribution of ionic and hydrophobic forces. Biochem. Pharmacol. 35:3761-3765.
-
(1986)
Biochem. Pharmacol
, vol.35
, pp. 3761-3765
-
-
Kubo, M.1
Gardner, M.F.2
Hostetler, K.Y.3
-
19
-
-
0023195793
-
Metabolic basis of diethylaminoethoxyhexestrol-induced phospholipid fatty liver
-
Kubo, M., and Hostetler, K. Y. 1987. Metabolic basis of diethylaminoethoxyhexestrol-induced phospholipid fatty liver. Am. J. Physiol. 252:E375-E379.
-
(1987)
Am. J. Physiol
, vol.252
-
-
Kubo, M.1
Hostetler, K.Y.2
-
20
-
-
0017857637
-
Lipidosis induced by amphiphilic cationic drugs
-
Lullmann, H., Lullmann-Rauch, R., and Wassermann, O. 1978. Lipidosis induced by amphiphilic cationic drugs. Biochem. Pharmacol. 27:1103-1108.
-
(1978)
Biochem. Pharmacol
, vol.27
, pp. 1103-1108
-
-
Lullmann, H.1
Lullmann-Rauch, R.2
Wassermann, O.3
-
21
-
-
0019190221
-
Studies on drug-induced lipidosis: Subcellular locatlization of phospholipids and cholesterol in the liver of rat treated with chloroquine or 4′,4′-bis (diethylaminoethoxy)-α, β-diethyldiphenylethane
-
Matsuzawa, Y., and Hostetler, K. Y. 1980. Studies on drug-induced lipidosis: subcellular locatlization of phospholipids and cholesterol in the liver of rat treated with chloroquine or 4′,4′-bis (diethylaminoethoxy)-α, β-diethyldiphenylethane. J. Lipid Res. 21:202-214.
-
(1980)
J. Lipid Res
, vol.21
, pp. 202-214
-
-
Matsuzawa, Y.1
Hostetler, K.Y.2
-
22
-
-
0033047391
-
Interactions of macrolide antibiotics (erythromycin A, roxithromycin, erythromycylamine [dirithromycin], and azithromycin) with phospholipids: Computer-aided conformational analysis and studies on acellular and cell culture models
-
Montenez, J.-P., Van Bambeke, F., Piret, J., Brasseur, R., Tulkens, P. M., and Mingeot-Leclercq, M.-P. 1999. Interactions of macrolide antibiotics (erythromycin A, roxithromycin, erythromycylamine [dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. Toxicol. Appl. Pharmacol. 156:129-140.
-
(1999)
Toxicol. Appl. Pharmacol
, vol.156
, pp. 129-140
-
-
Montenez, J.-P.1
Van Bambeke, F.2
Piret, J.3
Brasseur, R.4
Tulkens, P.M.5
Mingeot-Leclercq, M.-P.6
-
23
-
-
26244436660
-
Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: A case report
-
Oikawa, H., Maesawa, C., Sato, R., Oikawa, K., Yamada, H., Oriso, S., Ono, S., Yashima-Abo, A., Kotani, K., Suzuki, K., and Masuda, T. 2005. Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: a case report. World J. Gastroenterol. 11:5394-5397.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 5394-5397
-
-
Oikawa, H.1
Maesawa, C.2
Sato, R.3
Oikawa, K.4
Yamada, H.5
Oriso, S.6
Ono, S.7
Yashima-Abo, A.8
Kotani, K.9
Suzuki, K.10
Masuda, T.11
-
24
-
-
0018381333
-
Perhexiline maleate-induced cirrhosis
-
Pessayre, D., Bichara, M., Degott, C., Potet, F., Benhamou, J. P., and Feldmann, G. 1979. Perhexiline maleate-induced cirrhosis. Gastroenterology 76:170-177.
-
(1979)
Gastroenterology
, vol.76
, pp. 170-177
-
-
Pessayre, D.1
Bichara, M.2
Degott, C.3
Potet, F.4
Benhamou, J.P.5
Feldmann, G.6
-
25
-
-
0029822284
-
An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity
-
Reasor, M. J., and Kacew, S. 1996. An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity. Proc. Soc. Exp. Biol. Med. 212:297-304.
-
(1996)
Proc. Soc. Exp. Biol. Med
, vol.212
, pp. 297-304
-
-
Reasor, M.J.1
Kacew, S.2
-
26
-
-
0021927878
-
The pH dependence of disobutamide-induced clear cytoplasmic vacuoles in cultured cells
-
Ruben, Z., Anderson, S. N., Rorig, K. J., Hribar, J. D., and Bible, R. H. Jr. 1985. The pH dependence of disobutamide-induced clear cytoplasmic vacuoles in cultured cells. Proc. Soc. Exp. Biol. Med. 180:84-91.
-
(1985)
Proc. Soc. Exp. Biol. Med
, vol.180
, pp. 84-91
-
-
Ruben, Z.1
Anderson, S.N.2
Rorig, K.J.3
Hribar, J.D.4
Bible Jr., R.H.5
-
27
-
-
0024587380
-
Disobutamide: A model agent for investigating intracellular drug storage
-
Ruben, Z., Doss, D. C., Rorig, K. J., and Anderson, S. N. 1989. Disobutamide: a model agent for investigating intracellular drug storage. Toxicol. Appl. Pharmacol. 97:57-71.
-
(1989)
Toxicol. Appl. Pharmacol
, vol.97
, pp. 57-71
-
-
Ruben, Z.1
Doss, D.C.2
Rorig, K.J.3
Anderson, S.N.4
-
28
-
-
13644258653
-
A toxicogenomic approach to drug-induced phospholipidosis: Analysis of its induction mechanism and establishment of a novel in vitro screening system
-
Sawada, H., Takami, K., and Asahi, S. 2005. A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system.. Tox. Sci. 83:282-292.
-
(2005)
Tox. Sci
, vol.83
, pp. 282-292
-
-
Sawada, H.1
Takami, K.2
Asahi, S.3
-
29
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen, P. O. 1976. Preparation of isolated rat liver cells. Meth. Cell Biol. 13:29-83.
-
(1976)
Meth. Cell Biol
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
30
-
-
0020964939
-
Experimental phospholipidosis induced by 4′,4′-diethyl-aminoethoxyhexestrol. Morphological and biochemical interpretations
-
Tashiro, Y., Watanabe, Y., and Enomoto, Y. 1983. Experimental phospholipidosis induced by 4′,4′-diethyl-aminoethoxyhexestrol. Morphological and biochemical interpretations. Acta Pathol. Jpn. 33:929-942.
-
(1983)
Acta Pathol. Jpn
, vol.33
, pp. 929-942
-
-
Tashiro, Y.1
Watanabe, Y.2
Enomoto, Y.3
-
31
-
-
0001969538
-
An in vitro fluorescence assay for the detection of drug-induced cytoplasmic lamellar bodies
-
Ulrich, R. G., Kilgore, K. S., Sun, E. L., Cramer, C. T., and Ginsburg, L. C. 1991. An in vitro fluorescence assay for the detection of drug-induced cytoplasmic lamellar bodies. Tox. Methods. 1:89-105.
-
(1991)
Tox. Methods
, vol.1
, pp. 89-105
-
-
Ulrich, R.G.1
Kilgore, K.S.2
Sun, E.L.3
Cramer, C.T.4
Ginsburg, L.C.5
-
32
-
-
2542465772
-
Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence
-
Vonderfecht, S. L., Stone, M. L., Eversole, R. R., Yancey, M. F., Schuette, M. R., Duncan, B. A., and Ware, J. A. 2004. Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Tox. Pathol. 32:318-325.
-
(2004)
Tox. Pathol
, vol.32
, pp. 318-325
-
-
Vonderfecht, S.L.1
Stone, M.L.2
Eversole, R.R.3
Yancey, M.F.4
Schuette, M.R.5
Duncan, B.A.6
Ware, J.A.7
-
33
-
-
0033965926
-
Antidepressant-induced lipidosis with special reference to tricyclic compounds
-
Xia, A., Ying, F., Hansson, A. L., Karlsson, H., Xie, Y., Bergstrand, A., DePierre, J. W., and Nässberger, L. 2000. Antidepressant-induced lipidosis with special reference to tricyclic compounds. Prog. Neurobiol. 60:501-512.
-
(2000)
Prog. Neurobiol
, vol.60
, pp. 501-512
-
-
Xia, A.1
Ying, F.2
Hansson, A.L.3
Karlsson, H.4
Xie, Y.5
Bergstrand, A.6
DePierre, J.W.7
Nässberger, L.8
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