메뉴 건너뛰기




Volumn 21, Issue 3, 2007, Pages 242-254

Designing biological systems

Author keywords

Biological engineering; Genetic engineering; Metabolic engineering; Protein design; Synthetic biology

Indexed keywords

BIOLOGY; BIOSENSOR; CELL INTERACTION; DNA SYNTHESIS; GENE SWITCHING; GENOME; METABOLISM; NONHUMAN; OSCILLATOR; PRIORITY JOURNAL; PROTEIN ENGINEERING; REVIEW; SIGNAL TRANSDUCTION; STANDARDIZATION;

EID: 33846949751     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1507207     Document Type: Review
Times cited : (132)

References (107)
  • 1
    • 0344737581 scopus 로고    scopus 로고
    • Pharmacogenetic considerations in diseases of cardiac ion channels
    • Anantharam, A., Markowitz, S.M., and Abbott, G.W. 2003. Pharmacogenetic considerations in diseases of cardiac ion channels. J. Pharmacol. Exp. Ther. 307: 831-838.
    • (2003) J. Pharmacol. Exp. Ther , vol.307 , pp. 831-838
    • Anantharam, A.1    Markowitz, S.M.2    Abbott, G.W.3
  • 2
    • 29144482539 scopus 로고    scopus 로고
    • Environmentally controlled invasion of cancer cells by engineered bacteria
    • Anderson, J.C., Clarke, E.J., Arkin, A.P., and Voigt, C.A. 2006. Environmentally controlled invasion of cancer cells by engineered bacteria. J. Mol. Biol. 355: 619-627.
    • (2006) J. Mol. Biol , vol.355 , pp. 619-627
    • Anderson, J.C.1    Clarke, E.J.2    Arkin, A.P.3    Voigt, C.A.4
  • 3
    • 33745454125 scopus 로고    scopus 로고
    • Synthetic biology: New engineering rules for an emerging discipline
    • Andrianantoandro, E., Basu, S., Karig, D.K., and Weiss, R. 2006. Synthetic biology: New engineering rules for an emerging discipline. Mol. Syst. Biol. 2: 2006.0028.
    • (2006) Mol. Syst. Biol , vol.2 , pp. 0028
    • Andrianantoandro, E.1    Basu, S.2    Karig, D.K.3    Weiss, R.4
  • 4
    • 0035710816 scopus 로고    scopus 로고
    • Synthetic cell biology
    • Arkin, A.P. 2001. Synthetic cell biology. Curr. Opin. Biotechnol. 12: 638-644.
    • (2001) Curr. Opin. Biotechnol , vol.12 , pp. 638-644
    • Arkin, A.P.1
  • 5
    • 33845579099 scopus 로고    scopus 로고
    • Fast, cheap and somewhat in control
    • Arkin, A.P. and Fletcher, D.A. 2006. Fast, cheap and somewhat in control. Genome Biol. 7: 114.
    • (2006) Genome Biol , vol.7 , pp. 114
    • Arkin, A.P.1    Fletcher, D.A.2
  • 6
    • 4444256116 scopus 로고    scopus 로고
    • Regulatory circuit design and evolution using phage λ
    • Atsumi, S. and Little, J.W. 2004. Regulatory circuit design and evolution using phage λ. Genes & Dev. 18: 2086-2094.
    • (2004) Genes & Dev , vol.18 , pp. 2086-2094
    • Atsumi, S.1    Little, J.W.2
  • 7
    • 2342578714 scopus 로고    scopus 로고
    • Spatiotemporal control of gene expression with pulse-generating networks
    • Basu, S., Mehreja, R., Thiberge, S., Chen, M.T., and Weiss, R. 2004. Spatiotemporal control of gene expression with pulse-generating networks. Proc. Natl. Acad. Sci. 101: 6355-6360.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 6355-6360
    • Basu, S.1    Mehreja, R.2    Thiberge, S.3    Chen, M.T.4    Weiss, R.5
  • 8
    • 17844374314 scopus 로고    scopus 로고
    • A synthetic multicellular system for programmed pattern formation
    • Basu, S., Gerchman, Y., Collins, C.H., Arnold, F.H., and Weiss, R. 2005. A synthetic multicellular system for programmed pattern formation. Nature 434: 1130-1134.
    • (2005) Nature , vol.434 , pp. 1130-1134
    • Basu, S.1    Gerchman, Y.2    Collins, C.H.3    Arnold, F.H.4    Weiss, R.5
  • 9
    • 21444457242 scopus 로고    scopus 로고
    • Programmable ligand-controlled riboregulators of eukaryotic gene expression
    • Bayer, T.S. and Smolke, C.D. 2005. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat. Biotechnol. 23: 337-343.
    • (2005) Nat. Biotechnol , vol.23 , pp. 337-343
    • Bayer, T.S.1    Smolke, C.D.2
  • 10
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • Becskei, A. and Serrano, L. 2000. Engineering stability in gene networks by autoregulation. Nature 405: 590-593.
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 11
    • 17144456808 scopus 로고    scopus 로고
    • Positive feedback in eukaryotic gene networks: Cell differentiation by graded to binary response conversion
    • Becskei, A., Seraphin, B., and Serrano, L. 2001. Positive feedback in eukaryotic gene networks: Cell differentiation by graded to binary response conversion. EMBO J. 20: 2528-2535.
    • (2001) EMBO J , vol.20 , pp. 2528-2535
    • Becskei, A.1    Seraphin, B.2    Serrano, L.3
  • 12
    • 0037426848 scopus 로고    scopus 로고
    • Synthetic biology: Act natural
    • Benner, S.A. 2003. Synthetic biology: Act natural. Nature 421: 118.
    • (2003) Nature , vol.421 , pp. 118
    • Benner, S.A.1
  • 14
    • 0036193776 scopus 로고    scopus 로고
    • Golden Rice: Introducing the β-carotene biosynthesis pathway into rice endosperm by genetic engineering to defeat vitamin A deficiency
    • Beyer, P., Al-Babili, S., Ye, X., Lucca, P., Schaub, P., Welsch, R., and Potrykus, I. 2002. Golden Rice: Introducing the β-carotene biosynthesis pathway into rice endosperm by genetic engineering to defeat vitamin A deficiency. J. Nutr. 132: 506S-510S.
    • (2002) J. Nutr , vol.132
    • Beyer, P.1    Al-Babili, S.2    Ye, X.3    Lucca, P.4    Schaub, P.5    Welsch, R.6    Potrykus, I.7
  • 15
    • 33746363486 scopus 로고    scopus 로고
    • Domains, motifs, and scaffolds: The role of modular interactions in the evolution and wiring of cell signaling circuits
    • Bhattacharyya, R.P., Remenyi, A., Yeh, B.J., and Lim, W.A. 2006. Domains, motifs, and scaffolds: The role of modular interactions in the evolution and wiring of cell signaling circuits. Annu. Rev. Biochem. 75: 655-680.
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 655-680
    • Bhattacharyya, R.P.1    Remenyi, A.2    Yeh, B.J.3    Lim, W.A.4
  • 16
    • 33646173810 scopus 로고    scopus 로고
    • The engineer's approach to biology
    • Breithaupt, H. 2006. The engineer's approach to biology. EMBO Rep. 7: 21-23.
    • (2006) EMBO Rep , vol.7 , pp. 21-23
    • Breithaupt, H.1
  • 17
    • 5044239903 scopus 로고    scopus 로고
    • A partnership between biology and engineering
    • Brent, R. 2004. A partnership between biology and engineering. Nat. Biotechnol. 22: 1211-1214.
    • (2004) Nat. Biotechnol , vol.22 , pp. 1211-1214
    • Brent, R.1
  • 18
    • 1842591042 scopus 로고    scopus 로고
    • The pace and proliferation of biological technologies
    • Carlson, R. 2003. The pace and proliferation of biological technologies. Biosecur. Bioterror. 1: 203-214.
    • (2003) Biosecur. Bioterror , vol.1 , pp. 203-214
    • Carlson, R.1
  • 19
    • 0037047595 scopus 로고    scopus 로고
    • Chemical synthesis of poliovirus cDNA: Generation of infectious virus in the absence of natural template
    • Cello, J., Paul, A.V., and Wimmer, E. 2002. Chemical synthesis of poliovirus cDNA: Generation of infectious virus in the absence of natural template. Science 297: 1016-1018.
    • (2002) Science , vol.297 , pp. 1016-1018
    • Cello, J.1    Paul, A.V.2    Wimmer, E.3
  • 20
  • 21
    • 33751120932 scopus 로고    scopus 로고
    • Production of isoprenoid pharmaceuticals by engineered microbes
    • Chang, M.C. and Keasling, J.D. 2006. Production of isoprenoid pharmaceuticals by engineered microbes. Nat. Chem. Biol. 2: 674-681.
    • (2006) Nat. Chem. Biol , vol.2 , pp. 674-681
    • Chang, M.C.1    Keasling, J.D.2
  • 22
    • 28644440579 scopus 로고    scopus 로고
    • Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana
    • Chen, M.T. and Weiss, R. 2005. Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana. Nat. Biotechnol. 23: 1551-1555.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1551-1555
    • Chen, M.T.1    Weiss, R.2
  • 24
    • 33646877664 scopus 로고    scopus 로고
    • Modular approaches to expanding the functions of living matter
    • Chin, J.W. 2006a. Modular approaches to expanding the functions of living matter. Nat. Chem. Biol. 2: 304-311.
    • (2006) Nat. Chem. Biol , vol.2 , pp. 304-311
    • Chin, J.W.1
  • 25
    • 33746603530 scopus 로고    scopus 로고
    • Programming and engineering biological networks
    • Chin, J.W. 2006b. Programming and engineering biological networks. Curr. Opin. Struct. Biol. 16: 551-556.
    • (2006) Curr. Opin. Struct. Biol , vol.16 , pp. 551-556
    • Chin, J.W.1
  • 26
    • 0033866302 scopus 로고    scopus 로고
    • Measuring dimensions: The regulation of size and shape
    • Day, S.J. and Lawrence, P.A. 2000. Measuring dimensions: The regulation of size and shape. Development 127: 2977-2987.
    • (2000) Development , vol.127 , pp. 2977-2987
    • Day, S.J.1    Lawrence, P.A.2
  • 27
    • 20644453324 scopus 로고    scopus 로고
    • A giant step towards artificial life?
    • Deamer, D. 2005. A giant step towards artificial life? Trends Biotechnol. 23: 336-338.
    • (2005) Trends Biotechnol , vol.23 , pp. 336-338
    • Deamer, D.1
  • 29
    • 0141757323 scopus 로고    scopus 로고
    • Reprogramming control of an allosteric signaling switch through modular recombination
    • Dueber, J.E., Yeh, B.J., Chak, K., and Lim, W.A. 2003. Reprogramming control of an allosteric signaling switch through modular recombination. Science 301: 1904-1908.
    • (2003) Science , vol.301 , pp. 1904-1908
    • Dueber, J.E.1    Yeh, B.J.2    Chak, K.3    Lim, W.A.4
  • 30
    • 9944220618 scopus 로고    scopus 로고
    • Rewiring cell signaling: The logic and plasticity of eukaryotic protein circuitry
    • Dueber, J.E., Yeh, B.J., Bhattacharyya, R.P., and Lim, W.A. 2004. Rewiring cell signaling: The logic and plasticity of eukaryotic protein circuitry. Curr. Opin. Struct. Biol. 14: 690-699.
    • (2004) Curr. Opin. Struct. Biol , vol.14 , pp. 690-699
    • Dueber, J.E.1    Yeh, B.J.2    Bhattacharyya, R.P.3    Lim, W.A.4
  • 31
    • 4143115810 scopus 로고    scopus 로고
    • Periplasmic binding proteins: A versatile superfamily for protein engineering
    • Dwyer, M.A. and Hellinga, H.W. 2004. Periplasmic binding proteins: A versatile superfamily for protein engineering. Curr. Opin. Struct. Biol. 14: 495-504.
    • (2004) Curr. Opin. Struct. Biol , vol.14 , pp. 495-504
    • Dwyer, M.A.1    Hellinga, H.W.2
  • 32
    • 3042655537 scopus 로고    scopus 로고
    • Computational design of a biologically active enzyme
    • Dwyer, M.A., Looger, L.L., and Hellinga, H.W. 2004. Computational design of a biologically active enzyme. Science 304: 1967-1971.
    • (2004) Science , vol.304 , pp. 1967-1971
    • Dwyer, M.A.1    Looger, L.L.2    Hellinga, H.W.3
  • 33
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • Elowitz, M.B. and Leibler, S. 2000. A synthetic oscillatory network of transcriptional regulators. Nature 403: 335-338.
    • (2000) Nature , vol.403 , pp. 335-338
    • Elowitz, M.B.1    Leibler, S.2
  • 34
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • Elowitz, M.B., Levine, A.J., Siggia, E.D., and Swain, P.S. 2002. Stochastic gene expression in a single cell. Science 297: 1183-1186.
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 35
    • 28544451327 scopus 로고    scopus 로고
    • Foundations for engineering biology
    • Endy, D. 2005. Foundations for engineering biology. Nature 438: 449-453.
    • (2005) Nature , vol.438 , pp. 449-453
    • Endy, D.1
  • 36
    • 19744382857 scopus 로고    scopus 로고
    • Infectious diseases. Source of new hope against malaria is in short supply
    • Enserink, M. 2005. Infectious diseases. Source of new hope against malaria is in short supply. Science 307: 33.
    • (2005) Science , vol.307 , pp. 33
    • Enserink, M.1
  • 37
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • Ferrell Jr., J.E. 2002. Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability. Curr. Opin. Cell Biol. 14: 140-148.
    • (2002) Curr. Opin. Cell Biol , vol.14 , pp. 140-148
    • Ferrell Jr., J.E.1
  • 38
    • 33846108255 scopus 로고    scopus 로고
    • Towards synthesis of a minimal cell
    • Forster, A.C. and Church, G.M. 2006. Towards synthesis of a minimal cell. Mol. Syst. Biol. 2: 45.
    • (2006) Mol. Syst. Biol , vol.2 , pp. 45
    • Forster, A.C.1    Church, G.M.2
  • 39
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • Gardner, T.S., Cantor, C.R., and Collins, J.J. 2000. Construction of a genetic toggle switch in Escherichia coli. Nature 403: 339-342.
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 41
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M. and Bujard, H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. 89: 5547-5551.
    • (1992) Proc. Natl. Acad. Sci , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 42
    • 0029022369 scopus 로고
    • Transcriptional activation by tetracyclines in mammalian cells
    • Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W., and Bujard, H. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268: 1766-1769.
    • (1995) Science , vol.268 , pp. 1766-1769
    • Gossen, M.1    Freundlieb, S.2    Bender, G.3    Muller, G.4    Hillen, W.5    Bujard, H.6
  • 46
    • 0037079012 scopus 로고    scopus 로고
    • Engineered gene circuits
    • Hasty, J., McMillen, D., and Collins, J.J. 2002. Engineered gene circuits. Nature 420: 224-230.
    • (2002) Nature , vol.420 , pp. 224-230
    • Hasty, J.1    McMillen, D.2    Collins, J.J.3
  • 47
    • 33846959340 scopus 로고    scopus 로고
    • Synthetic biology - Putting engineering into biology
    • Heinemann, M. and Panke, S. 2006. Synthetic biology - Putting engineering into biology. Bioinformatics 7: 512.
    • (2006) Bioinformatics , vol.7 , pp. 512
    • Heinemann, M.1    Panke, S.2
  • 48
    • 30744443901 scopus 로고    scopus 로고
    • Prostratin as a new therapeutic agent targeting HIV viral reservoirs
    • Hezareh, M. 2005. Prostratin as a new therapeutic agent targeting HIV viral reservoirs. Drug News Perspect. 18: 496-500.
    • (2005) Drug News Perspect , vol.18 , pp. 496-500
    • Hezareh, M.1
  • 49
    • 14844358192 scopus 로고    scopus 로고
    • Ultrasensitivity and noise propagation in a synthetic transcriptional cascade
    • Hooshangi, S., Thiberge, S., and Weiss, R. 2005. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc. Natl. Acad. Sci. 102: 3581-3586.
    • (2005) Proc. Natl. Acad. Sci , vol.102 , pp. 3581-3586
    • Hooshangi, S.1    Thiberge, S.2    Weiss, R.3
  • 50
    • 0141483011 scopus 로고    scopus 로고
    • Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
    • Howard, P.L., Chia, M.C., Del Rizzo, S., Liu, F.F., and Pawson, T. 2003. Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins. Proc. Natl. Acad. Sci. 100: 11267-11272.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 11267-11272
    • Howard, P.L.1    Chia, M.C.2    Del Rizzo, S.3    Liu, F.F.4    Pawson, T.5
  • 53
    • 6344283046 scopus 로고    scopus 로고
    • Expression of a cascading genetic network within liposomes
    • Ishikawa, K., Sato, K., Shima, Y., Urabe, I., and Yomo, T. 2004. Expression of a cascading genetic network within liposomes. FEBS Lett. 576: 387-390.
    • (2004) FEBS Lett , vol.576 , pp. 387-390
    • Ishikawa, K.1    Sato, K.2    Shima, Y.3    Urabe, I.4    Yomo, T.5
  • 54
    • 54249116230 scopus 로고
    • Genetic regulatory mechanisms in the synthesis of proteins
    • Jacob, F. and Monod, J. 1961. Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3: 318-356.
    • (1961) J. Mol. Biol , vol.3 , pp. 318-356
    • Jacob, F.1    Monod, J.2
  • 56
    • 0346328227 scopus 로고    scopus 로고
    • Metabolic engineering for drug discovery and development
    • Khosla, C. and Keasling, J.D. 2003. Metabolic engineering for drug discovery and development. Nat. Rev. Drug Discov. 2: 1019-1025.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 1019-1025
    • Khosla, C.1    Keasling, J.D.2
  • 57
    • 0025153120 scopus 로고
    • Control of yeast mating signal transduction by a mammalian β 2-adrenergic receptor and Gs α subunit
    • King, K., Dohlman, H.G., Thorner, J., Caron, M.G., and Lefkowitz, R.J. 1990. Control of yeast mating signal transduction by a mammalian β 2-adrenergic receptor and Gs α subunit. Science 250: 121-123.
    • (1990) Science , vol.250 , pp. 121-123
    • King, K.1    Dohlman, H.G.2    Thorner, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 59
    • 33846989982 scopus 로고    scopus 로고
    • Knight, T. 2003. Idempotent vector design for standard assembly of biobricks. http://hdl.handle.net/1721.1/21168. In DSpace. Massachussetts Institute of Technology Artificial Intelligence Laboratory, MIT Synthetic Biology Working Group.
    • Knight, T. 2003. Idempotent vector design for standard assembly of biobricks. http://hdl.handle.net/1721.1/21168. In DSpace. Massachussetts Institute of Technology Artificial Intelligence Laboratory, MIT Synthetic Biology Working Group.
  • 60
    • 33746862975 scopus 로고    scopus 로고
    • Engineering novel life
    • Knight, T.F. 2005. Engineering novel life. Mol. Syst. Biol. 1: 2005.0020.
    • (2005) Mol. Syst. Biol , vol.1 , pp. 0020
    • Knight, T.F.1
  • 64
    • 22144452865 scopus 로고    scopus 로고
    • Hysteresis in a synthetic mammalian gene network
    • Kramer, B.P. and Fussenegger, M. 2005. Hysteresis in a synthetic mammalian gene network. Proc. Natl. Acad. Sci. 102: 9517-9522.
    • (2005) Proc. Natl. Acad. Sci , vol.102 , pp. 9517-9522
    • Kramer, B.P.1    Fussenegger, M.2
  • 66
    • 0345306764 scopus 로고    scopus 로고
    • Design of a novel globular protein fold with atomic-level accuracy
    • Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L., and Baker, D. 2003. Design of a novel globular protein fold with atomic-level accuracy. Science 302: 1364-1368.
    • (2003) Science , vol.302 , pp. 1364-1368
    • Kuhlman, B.1    Dantas, G.2    Ireton, G.C.3    Varani, G.4    Stoddard, B.L.5    Baker, D.6
  • 68
    • 0038752617 scopus 로고    scopus 로고
    • Computational design of receptor and sensor proteins with novel functions
    • Looger, L.L., Dwyer, M.A., Smith, J.J., and Hellinga, H.W. 2003. Computational design of receptor and sensor proteins with novel functions. Nature 423: 185-190.
    • (2003) Nature , vol.423 , pp. 185-190
    • Looger, L.L.1    Dwyer, M.A.2    Smith, J.J.3    Hellinga, H.W.4
  • 69
    • 0038391517 scopus 로고    scopus 로고
    • Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
    • Martin, V.J., Pitera, D.J., Withers, S.T., Newman, J.D., and Keasling, J.D. 2003. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat. Biotechnol. 21: 796-802.
    • (2003) Nat. Biotechnol , vol.21 , pp. 796-802
    • Martin, V.J.1    Pitera, D.J.2    Withers, S.T.3    Newman, J.D.4    Keasling, J.D.5
  • 70
    • 0031029852 scopus 로고    scopus 로고
    • Stochastic mechanisms in gene expression
    • McAdams, H.H. and Arkin, A. 1997. Stochastic mechanisms in gene expression. Proc. Natl. Acad. Sci. 94: 814-819.
    • (1997) Proc. Natl. Acad. Sci , vol.94 , pp. 814-819
    • McAdams, H.H.1    Arkin, A.2
  • 71
    • 23444461901 scopus 로고    scopus 로고
    • Advances in synthetic biology: On the path from prototypes to applications
    • McDaniel, R. and Weiss, R. 2005. Advances in synthetic biology: On the path from prototypes to applications. Curr. Opin. Biotechnol. 16: 476-483.
    • (2005) Curr. Opin. Biotechnol , vol.16 , pp. 476-483
    • McDaniel, R.1    Weiss, R.2
  • 73
    • 11144220854 scopus 로고    scopus 로고
    • A vesicle bioreactor as a step toward an artificial cell assembly
    • Noireaux, V. and Libchaber, A. 2004. A vesicle bioreactor as a step toward an artificial cell assembly. Proc. Natl. Acad. Sci. 101: 17669-17674.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 17669-17674
    • Noireaux, V.1    Libchaber, A.2
  • 74
    • 0037436155 scopus 로고    scopus 로고
    • Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms
    • Park, S.H., Zarrinpar, A., and Lim, W.A. 2003. Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299: 1061-1064.
    • (2003) Science , vol.299 , pp. 1061-1064
    • Park, S.H.1    Zarrinpar, A.2    Lim, W.A.3
  • 75
    • 14844321287 scopus 로고    scopus 로고
    • Synthetic modular systems - Reverse engineering of signal transduction
    • Pawson, T. and Linding, R. 2005. Synthetic modular systems - Reverse engineering of signal transduction. FEBS Lett. 579:1808-1814.
    • (2005) FEBS Lett , vol.579 , pp. 1808-1814
    • Pawson, T.1    Linding, R.2
  • 76
    • 15544388848 scopus 로고    scopus 로고
    • Noise propagation in gene networks
    • Pedraza, J.M. and van Oudenaarden, A. 2005. Noise propagation in gene networks. Science 307: 1965-1969.
    • (2005) Science , vol.307 , pp. 1965-1969
    • Pedraza, J.M.1    van Oudenaarden, A.2
  • 77
    • 0035102454 scopus 로고    scopus 로고
    • Biosynthesis of polyketides in heterologous hosts
    • Pfeifer, B.A. and Khosla, C. 2001. Biosynthesis of polyketides in heterologous hosts. Microbiol. Mol. Biol. Rev. 65: 106-118.
    • (2001) Microbiol. Mol. Biol. Rev , vol.65 , pp. 106-118
    • Pfeifer, B.A.1    Khosla, C.2
  • 78
    • 33846966513 scopus 로고    scopus 로고
    • Phillips, I. and Silver, P.A. 2006. A new biobrick assembly strategy designed for facile protein engineering. http://hdl.handle.net/1721.1/32535. In DSpace. Massachussetts Institute of Technology Artificial Intelligence Laboratory, MIT Synthetic Biology Working Group.
    • Phillips, I. and Silver, P.A. 2006. A new biobrick assembly strategy designed for facile protein engineering. http://hdl.handle.net/1721.1/32535. In DSpace. Massachussetts Institute of Technology Artificial Intelligence Laboratory, MIT Synthetic Biology Working Group.
  • 79
    • 0029875865 scopus 로고    scopus 로고
    • A model for the cooperative binding of eukaryotic regulatory proteins to nucleosomal target sites
    • Polach, K.J. and Widom, J. 1996. A model for the cooperative binding of eukaryotic regulatory proteins to nucleosomal target sites. J. Mol. Biol. 258: 800-812.
    • (1996) J. Mol. Biol , vol.258 , pp. 800-812
    • Polach, K.J.1    Widom, J.2
  • 81
    • 0034721696 scopus 로고    scopus 로고
    • Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex
    • Prehoda, K.E., Scott, J.A., Mullins, R.D., and Lim, W.A. 2000. Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex. Science 290: 801-806.
    • (2000) Science , vol.290 , pp. 801-806
    • Prehoda, K.E.1    Scott, J.A.2    Mullins, R.D.3    Lim, W.A.4
  • 82
    • 0028840683 scopus 로고
    • Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway
    • Price, L.A., Kajkowski, E.M., Hadcock, J.R., Ozenberger, B.A., and Pausch, M.H. 1995. Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol. Cell. Biol. 15: 6188-6195.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 6188-6195
    • Price, L.A.1    Kajkowski, E.M.2    Hadcock, J.R.3    Ozenberger, B.A.4    Pausch, M.H.5
  • 84
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • Raser, J.M. and O'Shea, E.K. 2004. Control of stochasticity in eukaryotic gene expression. Science 304: 1811-1814.
    • (2004) Science , vol.304 , pp. 1811-1814
    • Raser, J.M.1    O'Shea, E.K.2
  • 85
    • 25444468618 scopus 로고    scopus 로고
    • Noise in gene expression: Origins, consequences, and control
    • Raser, J.M. and O'Shea, E.K. 2005. Noise in gene expression: Origins, consequences, and control. Science 309: 2010-2013.
    • (2005) Science , vol.309 , pp. 2010-2013
    • Raser, J.M.1    O'Shea, E.K.2
  • 87
    • 0033574722 scopus 로고    scopus 로고
    • The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
    • Rohatgi, R., Ma, L., Miki, H., Lopez, M., Kirchhausen, T., Takenawa, T., and Kirschner, M.W. 1999. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97: 221-231.
    • (1999) Cell , vol.97 , pp. 221-231
    • Rohatgi, R.1    Ma, L.2    Miki, H.3    Lopez, M.4    Kirchhausen, T.5    Takenawa, T.6    Kirschner, M.W.7
  • 89
    • 0024429567 scopus 로고
    • A simple conversion of artemisinic acid into artemisinin
    • Roth, R.J. and Acton, N. 1989. A simple conversion of artemisinic acid into artemisinin. J. Nat. Prod. 52: 1183-1185.
    • (1989) J. Nat. Prod , vol.52 , pp. 1183-1185
    • Roth, R.J.1    Acton, N.2
  • 90
    • 0020577131 scopus 로고
    • Total synthesis of qinghaosu
    • Schmid, G. and Hofheinz, W. 1983. Total synthesis of qinghaosu. J. Am. Chem. Soc. 105: 624-625.
    • (1983) J. Am. Chem. Soc , vol.105 , pp. 624-625
    • Schmid, G.1    Hofheinz, W.2
  • 94
    • 0347364647 scopus 로고    scopus 로고
    • Generating a synthetic genome by whole genome assembly: φX174 bacteriophage from synthetic oligonucleotides
    • Smith, H.O., Hutchison III, C.A., Pfannkoch, C., and Venter, J.C. 2003. Generating a synthetic genome by whole genome assembly: φX174 bacteriophage from synthetic oligonucleotides. Proc. Natl. Acad. Sci. 100: 15440-15445.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 15440-15445
    • Smith, H.O.1    Hutchison III, C.A.2    Pfannkoch, C.3    Venter, J.C.4
  • 95
    • 28544440364 scopus 로고    scopus 로고
    • Reconstruction of genetic circuits
    • Sprinzak, D. and Elowitz, M.B. 2005. Reconstruction of genetic circuits. Nature 438: 443-448.
    • (2005) Nature , vol.438 , pp. 443-448
    • Sprinzak, D.1    Elowitz, M.B.2
  • 96
    • 0028784138 scopus 로고
    • Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides
    • Stemmer, W.P., Crameri, A., Ha, K.D., Brennan, T.M., and Heyneker, H.L. 1995. Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides. Gene 164: 49-53.
    • (1995) Gene , vol.164 , pp. 49-53
    • Stemmer, W.P.1    Crameri, A.2    Ha, K.D.3    Brennan, T.M.4    Heyneker, H.L.5
  • 98
    • 0018032871 scopus 로고
    • Nobel prizes and restriction enzymes
    • Szybalski, W. and Skalka, A. 1978. Nobel prizes and restriction enzymes. Gene 4: 181-182.
    • (1978) Gene , vol.4 , pp. 181-182
    • Szybalski, W.1    Skalka, A.2
  • 99
    • 11144247743 scopus 로고    scopus 로고
    • Accurate multiplex gene synthesis from programmable DNA microchips
    • Tian, J., Gong, H., Sheng, N., Zhou, X., Gulari, E., Gao, X., and Church, G. 2004. Accurate multiplex gene synthesis from programmable DNA microchips. Nature 432: 1050-1054.
    • (2004) Nature , vol.432 , pp. 1050-1054
    • Tian, J.1    Gong, H.2    Sheng, N.3    Zhou, X.4    Gulari, E.5    Gao, X.6    Church, G.7
  • 100
    • 33746199797 scopus 로고    scopus 로고
    • The promise and perils of synthetic biology
    • Tucker, J.B. and Zilinskas, R.A. 2006. The promise and perils of synthetic biology. New Atlantis 12: 25-45.
    • (2006) New Atlantis , vol.12 , pp. 25-45
    • Tucker, J.B.1    Zilinskas, R.A.2
  • 102
    • 0032499071 scopus 로고    scopus 로고
    • Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions
    • Vashee, S., Melcher, K., Ding, W.V., Johnston, S.A., and Kodadek, T. 1998. Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions. Curr. Biol. 8: 452-458.
    • (1998) Curr. Biol , vol.8 , pp. 452-458
    • Vashee, S.1    Melcher, K.2    Ding, W.V.3    Johnston, S.A.4    Kodadek, T.5
  • 103
    • 0041825399 scopus 로고    scopus 로고
    • Design principles for regulator gene expression in a repressible gene circuit
    • Wall, M.E., Hlavacek, W.S., and Savageau, M.A. 2003. Design principles for regulator gene expression in a repressible gene circuit. J. Mol. Biol. 332: 861-876.
    • (2003) J. Mol. Biol , vol.332 , pp. 861-876
    • Wall, M.E.1    Hlavacek, W.S.2    Savageau, M.A.3
  • 104
    • 0346728474 scopus 로고    scopus 로고
    • Design of gene circuits: Lessons from bacteria
    • Wall, M.E., Hlavacek, W.S., and Savageau, M.A. 2004. Design of gene circuits: Lessons from bacteria. Nat. Rev. Genet. 5: 34-42.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 34-42
    • Wall, M.E.1    Hlavacek, W.S.2    Savageau, M.A.3
  • 105
    • 0033582718 scopus 로고    scopus 로고
    • A mathematical model for synergistic eukaryotic gene activation
    • Wang, J., Ellwood, K., Lehman, A., Carey, M.F., and She, Z.S. 1999. A mathematical model for synergistic eukaryotic gene activation. J. Mol. Biol. 286: 315-325.
    • (1999) J. Mol. Biol , vol.286 , pp. 315-325
    • Wang, J.1    Ellwood, K.2    Lehman, A.3    Carey, M.F.4    She, Z.S.5
  • 107
    • 0033983338 scopus 로고    scopus 로고
    • Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
    • Ye, X., Al-Babili, S., Kloti, A., Zhang, J., Lucca, P., Beyer, P., and Potrykus, I. 2000. Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287: 303-305.
    • (2000) Science , vol.287 , pp. 303-305
    • Ye, X.1    Al-Babili, S.2    Kloti, A.3    Zhang, J.4    Lucca, P.5    Beyer, P.6    Potrykus, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.