Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia

Orphanet Journal of Rare Diseases

Volumn 1, Issue 1, 2006, Pages

  Girschick, H J ^a   Schneider, P ^a   Haubitz, I ^a   Hiort, O ^b   Collmann, H ^a   Beer, M ^a   Shin, Y S ^c   Seyberth, H W ^d  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM PYROPHOSPHATE; MELOXICAM; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PYRIDOXAL 5 PHOSPHATE; THIAZINE DERIVATIVE; THIAZOLE DERIVATIVE;

ADOLESCENT; ARTICLE; BONE; CASE REPORT; CHILD; DOSE RESPONSE; DRUG EFFECT; FIBROBLAST; HUMAN; HYPOPHOSPHATASIA; IN VITRO STUDY; MALE; METABOLISM; PRESCHOOL CHILD; URINE;

ADOLESCENT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BONE AND BONES; CALCIUM PYROPHOSPHATE; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HUMANS; HYPOPHOSPHATASIA; MALE; NAPROXEN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; PYRIDOXAL PHOSPHATE; THIAZINES; THIAZOLES;

EID: 33846943140     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/1750-1172-1-24     Document Type: Article

References (28)

1. Infantile hypophosphatasia: localization within chromosome region 1p36.1-34 and prenatal diagnosis using linked DNA markers. CR Greenberg JA Evans S McKendry-Smith S Redekopp JC Haworth R Mulivor BN Chodirker, Am J Hum Genet 1990 46 2 286 292 1689104
2. Missense mutations of the tissue-nonspecific alkaline phosphatase gene in hypophosphatasia. PS Henthorn MP Whyte, Clin Chem 1992 38 12 2501 2505 1360878
3. Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia. PS Henthorn M Raducha KN Fedde MA Lafferty MP Whyte, Proc Natl Acad Sci U S A 1992 89 20 9924 9928 1409720 10.1073/pnas.89.20.9924
4. Heritable metabolic and dysplastic bone diseases. MP Whyte, Endocrinol Metab Clin North Am 1990 19 1 133 173 2113470
5. Hypophosphatasia: levels of bone alkaline phosphatase immunoreactivity in serum reflect disease severity. MP Whyte DA Walkenhorst KN Fedde PS Henthorn CS Hill, J Clin Endocrinol Metab 1996 81 6 2142 2148 10.1210/jc.81.6.2142 8964842
6. First identification of a gene defect for hypophosphatasia: evidence that alkaline phosphatase acts in skeletal mineralization. MJ Weiss DE Cole K Ray MP Whyte MA Lafferty R Mulivor H Harris, Connect Tissue Res 1989 21 1-4 99 104 discussion 104-106. 2605956
7. A clinical and research protocol for characterizing patients with hypophosphatasia. CC Hu DL King HF Thomas JP Simmer, Pediatr Dent 1996 18 1 17 23 8668564
8. Correlations of genotype and phenotype in hypophosphatasia. L Zurutuza F Muller JF Gibrat A Taillandier B Simon-Bouy JL Serre E Mornet, Hum Mol Genet 1999 8 6 1039 1046 10.1093/hmg/8.6.1039 10332035
9. Mutational analysis and functional correlation with phenotype in German patients with childhood-type hypophosphatasia. H Orimo HJ Girschick M Goseki-Sone M Ito K Oda T Shimada, J Bone Miner Res 2001 16 12 2313 2319 10.1359/jbmr.2001.16.12.2313 11760847
10. Serum alkaline phosphatase, serum pyrophosphatase, phosphorylethanolamine and inorganic pyrophosphate in plasma and urine. A genetic and clinical study of hypophosphatasia. SA Sorensen H Flodgaard E Sorensen, Monogr Hum Genet 1978 10 66 69 214699
11. Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism. MP Whyte JD Mahuren LA Vrabel SP Coburn, J Clin Invest 1985 76 2 752 756 4031070
12. Osteoarthritis and crystal deposition diseases. KD Brandt HR Schumacher Jr, Curr Opin Rheumatol 1993 5 4 483 486 8357744
13. Inorganic pyrophosphate in metabolic diseases predisposing to calcium pyrophosphate dihydrate crystal deposition. M Doherty A Chuck D Hosking E Hamilton, Arthritis Rheum 1991 34 10 1297 1303 1657004
14. Effect of synthetic calcium pyrophosphate and hydroxyapatite crystals on the interaction of human blood mononuclear cells with chondrocytes, synovial cells, and fibroblasts. JM Dayer V Evequoz C Zavadil-Grob MD Grynpas PT Cheng J Schnyder U Trechsel H Fleisch, Arthritis Rheum 1987 30 12 1372 1381 2829929
15. Release of collagenase, neutral protease, and prostaglandins from cultured mammalian synovial cells by hydroxyapatite and calcium pyrophosphate dihydrate crystals. HS Cheung PB Halverson DJ McCarty, Arthritis Rheum 1981 24 11 1338 1344 6274359
16. Prostaglandin (PG) E2 generation by cultured canine synovial fibroblasts exposed to microcrystals containing calcium. DJ McCarty HS Cheung, Ann Rheum Dis 1985 44 5 316 320 2988464
17. Treatment of childhood hypophosphatasia with nonsteroidal antiinflammatory drugs. HJ Girschick HW Seyberth HI Huppertz, Bone 1999 25 5 603 607 10.1016/S8756-3282(99)00203-3 10574582
18. Potential impact of selective cyclooxygenase-2 inhibitors on bone metabolism in health and disease. LG Raisz, Am J Med 2001 110 Suppl 3A 43S 45S 10.1016/S0002-9343(00)00684-7 11173049
19. Prostaglandins and bone: physiology and pathophysiology. LG Raisz, Osteoarthritis Cartilage 1999 7 4 419 421 10.1053/joca.1998.0230 10419786
20. Periosteal hyperostosis resulting from prostaglandin therapy. JL Williams, Eur J Radiol 1986 6 3 231 232 3769947
21. Bone metabolism and bone mineral density in childhood hypophosphatasia. HJ Girschick P Schneider K Kruse HI Huppertz, Bone 1999 25 3 361 367 10.1016/S8756-3282(99)00164-7 10495141
22. Pyridoxal-5'-phosphate determination by a sensitive micromethod in human blood, urine and tissues; its relation to cystathioninuria in neuroblastoma and biliary atresia. YS Shin R Rasshofer B Friedrich W Endres, Clin Chim Acta 1983 127 1 77 85 10.1016/0009-8981(83)90077-3 6825312
23. Increased urinary excretion of collagen crosslinks in girls with Ullrich-Turner syndrome. F Rauch M Seibel H Woitge K Kruse E Schonau, Acta Paediatr 1995 84 1 66 69 7734903
24. [Bullae, erosions and scars in the face of 2 girls with idiopathic arthritis. Naproxen-induced pseudoporphyria]. SG Schad H Hamm HJ Girschick, Hautarzt 2002 53 1 51 53 10.1007/s105-002-8049-2 11963225
25. Role of prostaglandins in hyperprostaglandin E syndrome and in selected renal tubular disorders. HW Seyberth SJ Koniger W Rascher PG Kuhl H Schweer, Pediatr Nephrol 1987 1 3 491 497 10.1007/BF00849259 3153322
26. How could infectious agents hide in synovial cells? Possible mechanisms of persistent viral infection in a model for the etiopathogenesis of chronic arthritis. HI Huppertz, Rheumatol Int 1994 14 2 71 75 10.1007/BF00300250 7824838
27. RAG1 and RAG2 expression by B cell subsets from human tonsil and peripheral blood. HJ Girschick AC Grammer T Nanki M Mayo PE Lipsky, J Immunol 2001 166 1 377 386 11123315
28. Differential expression of matrix metalloproteinases and cyclooxygenases in synovial cells infected with different Borrelia burgdorferi isolates. SK Singh H Morbach T Nanki C Faber V Baar A Wirsing HJ Girschick, Inflamm Res 2004 53 689 696 10.1007/s00011-004-1313-x 15654517