Synthesis of new 1-(amino)-3-[(1,5-diphenyl-1H-1,2,4-triazol-3-yl) oxy] propan-2-ol and 1-[(1,5-diphenyl-1H-1,2,4-triazol-3-yl) oxy]-3-(4-arylpiperazin- 1-yl) propan-2-ol derivatives with an expected β-adrenolytic activity

Acta Poloniae Pharmaceutica - Drug Research

Volumn 63, Issue 4, 2006, Pages 255-259

  Kossakowski, Jerzy ^a   Struga, Marta ^a   Kozioł, Anna E ^b  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

Author keywords

adrenoceptor; 1,5 diphenyl 1H 1,2,4 triazol 3 ol; H3 CGP 12177 binding; Substitution reaction; X ray structure analysis

Indexed keywords

1 (AMINO) 3 [(1,5 DIPHENYL 1H 1,2,4 TRIAZOL 3 YL)OXY]PROPAN 2 OL; ALKANOL; BIPHENYL DERIVATIVE; ETHYLENE OXIDE DERIVATIVE; PIPERAZINE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROPANOL; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; LIGAND; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; BIOTRANSFORMATION; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LIGAND BINDING; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RECEPTOR AFFINITY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; ANIMAL; BRAIN CORTEX; CHEMICAL STRUCTURE; DRUG EFFECT; IN VITRO STUDY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; SYNTHESIS;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CEREBRAL CORTEX; INDICATORS AND REAGENTS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PIPERAZINES; PROPANOLS; PROPRANOLOL; RADIOLIGAND ASSAY; RATS; TRIAZOLES;

EID: 33846934754     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)