When it's hard to breathe, maybe pain doesn't matter. Focus on "Dyspnea as a noxious sensation: Inspiratory threshold loading may trigger diffuse noxious inhibitory controls in Humans"

Journal of Neurophysiology

Volumn 97, Issue 2, 2007, Pages 959-960

  Banzett, Robert B ^a,b,c   Gracely, Richard H ^d   Lansing, Robert W ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREATHING; DYSPNEA; EDITORIAL; HUMAN; INSPIRATORY CAPACITY; NEUROPHYSIOLOGY; NOCICEPTION; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; PAIN; PRIORITY JOURNAL;

DYSPNEA; HUMANS; NOCICEPTORS; PAIN; RESPIRATORY MECHANICS; SIGNAL TRANSDUCTION;

EID: 33846933465     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00970.2006     Document Type: Editorial

References (8)

1. Banzett R, Lansing R. Respiratory sensations arising from chemoreceptors and pulmonary receptors: air hunger and lung volume. In: Respiratory Sensation, edited by Adams L and Guz A. New York: Marcel Dekker, 1996, p. 155-180.
2. Banzett RB, Mulnier HE, Murphy K, Rosen SD, Wise RJ, Adams L. Breathlessness in humans activates insular cortex. Neuroreport 11: 2117-2120, 2000.
3. Comroe JH. Dyspnea. Mod Concepts Cardiovasc Dis 25: 347-349, 1956.
4. Evans KC, Banzett RB, Adams L, McKay L, Frackowiak RS, Corfield DR. BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger. J Neurophysiol 88: 1500-1511, 2002.
5. Lansing RW, Im BS, Thwing JI, Legedza AT, Banzett RB. The perception of respiratory work and effort can be independent of the perception of air hunger. Am J Respir Crit Care Med 162: 1690-1696, 2000.
6. Morélot-Panzini C, Demoule A, Straus C, Zelter M, Derenne J-P, Willer J-C, Similowski T. Dyspnea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans. J Neurophysiol 97: 1396-1404, 2006.
7. Nishino T, Shimoyama N, Ide T, Isono S. Experimental pain augments experimental dyspnea, but not vice versa in human volunteers. Anesthesiology 91: 1633-1638, 1999.
8. Peiffer C, Poline JB, Thivard L, Aubier M, Samson Y. Neural substrates for the perception of acutely induced dyspnea. Am J Respir Crit Care Med 163: 951-957, 2001.