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Volumn 6, Issue 1, 2007, Pages 111-121

Combination vaccines: Synergistic simultaneous induction of antibody and T-cell immunity

Author keywords

Antibodies; Malaria; Recombinant; Subunit; T cell; Vaccine

Indexed keywords

ADENOVIRUS VECTOR; ALUMINUM POTASSIUM SULFATE; ALUMINUM SALT; ANTIGEN; AS 02A; DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS VACCINE; DIPHTHERIA PERTUSSIS TETANUS HAEMOPHILUS INFLUENZAE TYPE B VACCINE; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; IMMUNOLOGICAL ADJUVANT; LIPOSOME; MALARIA POXVIRUS PLUS PROTEIN SUBUNIT VACCINE; MALARIA VACCINE; MONTANIDE; N ACETYLMURAMYLALANYL DEXTRO ISOGLUTAMINYLALANYL DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; NAKED DNA; POLYGLACTIN; PROTOZOAL VACCINE; RECOMBINANT HEPATITIS B VACCINE; UNCLASSIFIED DRUG; VACCINIA VACCINE; VIROSOME; VIRUS VACCINE; VIRUS VECTOR;

EID: 33846930662     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.6.1.111     Document Type: Review
Times cited : (12)

References (94)
  • 1
    • 0034231842 scopus 로고    scopus 로고
    • The Global Alliance for Vaccines and Immunization - a millennial challenge
    • Nossal GJ. The Global Alliance for Vaccines and Immunization - a millennial challenge. Nat. Immunol. 1(1), 5-8 (2000).
    • (2000) Nat. Immunol , vol.1 , Issue.1 , pp. 5-8
    • Nossal, G.J.1
  • 2
    • 2442648963 scopus 로고    scopus 로고
    • A healthier climate for the funding of vaccine research
    • Nossal GJ. A healthier climate for the funding of vaccine research. Nat. Immunol. 5(5), 457-459 (2004).
    • (2004) Nat. Immunol , vol.5 , Issue.5 , pp. 457-459
    • Nossal, G.J.1
  • 3
    • 0037029861 scopus 로고    scopus 로고
    • Development of a DNA-MVA/HIVA vaccine for Kenya
    • Hanke T, McMichael AJ, Mwau M et al. Development of a DNA-MVA/HIVA vaccine for Kenya. Vaccine 20(15), 1995-1998 (2002).
    • (2002) Vaccine , vol.20 , Issue.15 , pp. 1995-1998
    • Hanke, T.1    McMichael, A.J.2    Mwau, M.3
  • 4
    • 2942549544 scopus 로고    scopus 로고
    • Progress in DNA-based heterologous prime-boost immunization strategies for malaria
    • Moore AC, Hill AV. Progress in DNA-based heterologous prime-boost immunization strategies for malaria. Immunol. Rev. 199, 126-143 (2004).
    • (2004) Immunol. Rev , vol.199 , pp. 126-143
    • Moore, A.C.1    Hill, A.V.2
  • 5
    • 0031924077 scopus 로고    scopus 로고
    • + T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara
    • + T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat. Med. 4(4), 397-402 (1998).
    • (1998) Nat. Med , vol.4 , Issue.4 , pp. 397-402
    • Schneider, J.1    Gilbert, S.C.2    Blanchard, T.J.3
  • 6
    • 0033178522 scopus 로고    scopus 로고
    • Immune effector mechanisms in malaria
    • Good MF, Doolan DL. Immune effector mechanisms in malaria. Curr. Opin. Immunol. 11(4), 412-419 (1999).
    • (1999) Curr. Opin. Immunol , vol.11 , Issue.4 , pp. 412-419
    • Good, M.F.1    Doolan, D.L.2
  • 7
    • 0036221435 scopus 로고    scopus 로고
    • Prospects for vaccine protection against HIV-1 infection and AIDS
    • Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS. Ann. Rev. Immunol. 20, 73-99 (2002).
    • (2002) Ann. Rev. Immunol , vol.20 , pp. 73-99
    • Letvin, N.L.1    Barouch, D.H.2    Montefiori, D.C.3
  • 8
    • 1042268186 scopus 로고    scopus 로고
    • Igietseme JU, Eko FO, He H, Black CM. Antibody regulation of T-cell immunity: implications for vaccine strategies against intracellular pathogens. Expert Rev. Vaccines 3(1), 23-34 (2003). • Outlines the essential role of antibodies in complementing the T-cell response to intracellular pathogens.
    • Igietseme JU, Eko FO, He H, Black CM. Antibody regulation of T-cell immunity: implications for vaccine strategies against intracellular pathogens. Expert Rev. Vaccines 3(1), 23-34 (2003). • Outlines the essential role of antibodies in complementing the T-cell response to intracellular pathogens.
  • 9
    • 0035314003 scopus 로고    scopus 로고
    • Immunity against cancer: Lessons learned from melanoma
    • Houghton AN, Gold JS, Blachere NE. Immunity against cancer: lessons learned from melanoma. Curr. Opin. Immunol. 13(2), 134-140 (2001).
    • (2001) Curr. Opin. Immunol , vol.13 , Issue.2 , pp. 134-140
    • Houghton, A.N.1    Gold, J.S.2    Blachere, N.E.3
  • 10
    • 18844463657 scopus 로고    scopus 로고
    • Improving protective immunity induced by DNA-based immunization: Priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus
    • Sedegah M, Weiss W, Sacci JB Jr et al. Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus. J. Immunol. 164(11), 5905-5912 (2000).
    • (2000) J. Immunol , vol.164 , Issue.11 , pp. 5905-5912
    • Sedegah, M.1    Weiss, W.2    Sacci Jr, J.B.3
  • 12
    • 21244440958 scopus 로고    scopus 로고
    • Hutchings CL, Gilbert SC, Hill AV, Moore AC. Novel protein and poxvirus-based vaccine combinations for simultaneous induction of humoral and cell-mediated immunity. J. Immunol. 175(1), 599-606 (2005). •• The first study to demonstrate the enhanced T-cell and antibody responses induced by combining and concurrently immunizing with a poxvirus-based and subunit protein vaccine.
    • Hutchings CL, Gilbert SC, Hill AV, Moore AC. Novel protein and poxvirus-based vaccine combinations for simultaneous induction of humoral and cell-mediated immunity. J. Immunol. 175(1), 599-606 (2005). •• The first study to demonstrate the enhanced T-cell and antibody responses induced by combining and concurrently immunizing with a poxvirus-based and subunit protein vaccine.
  • 13
    • 0034967907 scopus 로고    scopus 로고
    • The economic burden of malaria
    • Gallup JL, Sachs JD. The economic burden of malaria. Am. J. Trop. Med. Hyg. 64(Suppl. 1-2), 85-96 (2001).
    • (2001) Am. J. Trop. Med. Hyg , vol.64 , Issue.SUPPL. 1-2 , pp. 85-96
    • Gallup, J.L.1    Sachs, J.D.2
  • 14
    • 15044338866 scopus 로고    scopus 로고
    • The global distribution of clinical episodes of Plasmodium falciparum malaria
    • Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434(7030), 214-217 (2005).
    • (2005) Nature , vol.434 , Issue.7030 , pp. 214-217
    • Snow, R.W.1    Guerra, C.A.2    Noor, A.M.3    Myint, H.Y.4    Hay, S.I.5
  • 15
    • 0033756238 scopus 로고    scopus 로고
    • Malaria. A renewed assault on an old and deadly foe
    • Marshall E. Malaria. A renewed assault on an old and deadly foe. Science 290(5491), 428-430 (2000).
    • (2000) Science , vol.290 , Issue.5491 , pp. 428-430
    • Marshall, E.1
  • 16
    • 0034044126 scopus 로고    scopus 로고
    • The immunology of malaria infection
    • Plebanski M, Hill AV. The immunology of malaria infection. Curr. Opin. Immunol. 12(4), 437-441 (2000).
    • (2000) Curr. Opin. Immunol , vol.12 , Issue.4 , pp. 437-441
    • Plebanski, M.1    Hill, A.V.2
  • 17
    • 0031893942 scopus 로고    scopus 로고
    • Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria
    • Bull PC, Lowe BS, Kortok M et al. Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria. Nat. Med. 4(3), 358-360 (1998).
    • (1998) Nat. Med , vol.4 , Issue.3 , pp. 358-360
    • Bull, P.C.1    Lowe, B.S.2    Kortok, M.3
  • 18
    • 0035013082 scopus 로고    scopus 로고
    • Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children
    • Dodoo D, Staalsoe T, Giha H et al. Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children. Infect. Immun. 69(6), 3713-3718 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.6 , pp. 3713-3718
    • Dodoo, D.1    Staalsoe, T.2    Giha, H.3
  • 19
    • 0015699215 scopus 로고
    • Immunization of man against sporozite-induced Falciparum malaria
    • Clyde DF, Most H, McCarthy VC, Vanderberg JP. Immunization of man against sporozite-induced Falciparum malaria. Am. J. Med. Sci. 266(3), 169-177 (1973).
    • (1973) Am. J. Med. Sci , vol.266 , Issue.3 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.C.3    Vanderberg, J.P.4
  • 20
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei
    • Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 216(5111), 160-162 (1967).
    • (1967) Nature , vol.216 , Issue.5111 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 21
    • 20144387467 scopus 로고    scopus 로고
    • Webster DP, Dunachie S, Vuola JM et al. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc. Natl Acad. Sci. USA 102(13), 4836-4841 (2005). • The first report of sterile protection against malaria with vectored vaccines in a sporozoite challenge study. One volunteer showed sterile protection that was maintained at 20 months after vaccination and was associated with circulating central memory T cells.
    • Webster DP, Dunachie S, Vuola JM et al. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc. Natl Acad. Sci. USA 102(13), 4836-4841 (2005). • The first report of sterile protection against malaria with vectored vaccines in a sporozoite challenge study. One volunteer showed sterile protection that was maintained at 20 months after vaccination and was associated with circulating central memory T cells.
  • 22
    • 17644370329 scopus 로고    scopus 로고
    • Cell biology of antigen processing in vitro and in vivo
    • Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Ann. Rev. Immunol. 23, 975-1028 (2005).
    • (2005) Ann. Rev. Immunol , vol.23 , pp. 975-1028
    • Trombetta, E.S.1    Mellman, I.2
  • 23
    • 0026768140 scopus 로고
    • Poliovirus-specific major histocompatibility complex class I-restricted cytolytic T-cell epitopes in mice localize to neutralizing antigenic regions
    • Kutubuddin M, Simons J, Chow M. Poliovirus-specific major histocompatibility complex class I-restricted cytolytic T-cell epitopes in mice localize to neutralizing antigenic regions. J. Virol. 66(10), 5967-5974 (1992).
    • (1992) J. Virol , vol.66 , Issue.10 , pp. 5967-5974
    • Kutubuddin, M.1    Simons, J.2    Chow, M.3
  • 24
    • 0028057715 scopus 로고
    • Antibody and cytotoxic T-cell responses to soluble hepatitis B virus (HBV) S antigen in mice: Implication for the pathogenesis of HBV-induced hepatitis
    • Schirmbeck R, Melber K, Mertens T, Reimann J. Antibody and cytotoxic T-cell responses to soluble hepatitis B virus (HBV) S antigen in mice: implication for the pathogenesis of HBV-induced hepatitis. J. Virol. 68(3), 1418-1425 (1994).
    • (1994) J. Virol , vol.68 , Issue.3 , pp. 1418-1425
    • Schirmbeck, R.1    Melber, K.2    Mertens, T.3    Reimann, J.4
  • 25
    • 0023103691 scopus 로고
    • Purified influenza virus nucleoprotein protects mice from lethal infection
    • Wraith DC, Vessey AE, Askonas BA. Purified influenza virus nucleoprotein protects mice from lethal infection. J. Gen. Virol. 68(Pt 2), 433-440 (1987).
    • (1987) J. Gen. Virol , vol.68 , Issue.PART 2 , pp. 433-440
    • Wraith, D.C.1    Vessey, A.E.2    Askonas, B.A.3
  • 26
    • 0022261151 scopus 로고
    • Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coli
    • Yamada A, Ziese MR, Young JF, Yamada YK, Ennis FA. Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coli. J. Exp. Med. 162(2), 663-674 (1985).
    • (1985) J. Exp. Med , vol.162 , Issue.2 , pp. 663-674
    • Yamada, A.1    Ziese, M.R.2    Young, J.F.3    Yamada, Y.K.4    Ennis, F.A.5
  • 27
    • 0033522812 scopus 로고    scopus 로고
    • The adjuvant combination monophosphoryl lipid A and QS21 switches T cell responses induced with a soluble recombinant HIV protein from Th2 to Th1
    • Moore A, McCarthy L, Mills KH. The adjuvant combination monophosphoryl lipid A and QS21 switches T cell responses induced with a soluble recombinant HIV protein from Th2 to Th1. Vaccine 17(20-21), 2517-2527 (1999).
    • (1999) Vaccine , vol.17 , Issue.20-21 , pp. 2517-2527
    • Moore, A.1    McCarthy, L.2    Mills, K.H.3
  • 28
    • 0026713158 scopus 로고
    • Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines
    • Nair S, Zhou X, Huang L, Rouse BT. Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines. J. Immunol. Methods 152(2), 237-243 (1992).
    • (1992) J. Immunol. Methods , vol.152 , Issue.2 , pp. 237-243
    • Nair, S.1    Zhou, X.2    Huang, L.3    Rouse, B.T.4
  • 29
    • 0025806703 scopus 로고
    • Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route
    • Mowat AM, Donachie AM, Reid G, Jarrett O. Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology 72(3), 317-322 (1991).
    • (1991) Immunology , vol.72 , Issue.3 , pp. 317-322
    • Mowat, A.M.1    Donachie, A.M.2    Reid, G.3    Jarrett, O.4
  • 30
    • 0025310910 scopus 로고
    • + cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs
    • + cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Nature 344(6269), 873-875 (1990).
    • (1990) Nature , vol.344 , Issue.6269 , pp. 873-875
    • Takahashi, H.1    Takeshita, T.2    Morein, B.3
  • 31
    • 0026762981 scopus 로고
    • Measles virus transmembrane fusion protein synthesized de novo or presented in immunostimulating complexes is endogenously processed for HLA class I- and class II-restricted cytotoxic T cell recognition
    • van Binnendijk RS, van Baalen CA, Poelen MC et al. Measles virus transmembrane fusion protein synthesized de novo or presented in immunostimulating complexes is endogenously processed for HLA class I- and class II-restricted cytotoxic T cell recognition. J. Exp. Med. 176(1), 119-128 (1992).
    • (1992) J. Exp. Med , vol.176 , Issue.1 , pp. 119-128
    • van Binnendijk, R.S.1    van Baalen, C.A.2    Poelen, M.C.3
  • 32
    • 17644416719 scopus 로고    scopus 로고
    • Targeting the innate immune response with improved vaccine adjuvants
    • Pashine A, Valiante NM, Ulmer JB. Targeting the innate immune response with improved vaccine adjuvants. Nat. Med. 11(Suppl. 4), S63-S68 (2005).
    • (2005) Nat. Med , vol.11 , Issue.SUPPL. 4
    • Pashine, A.1    Valiante, N.M.2    Ulmer, J.B.3
  • 33
    • 28844483001 scopus 로고    scopus 로고
    • Alonso PL, Sacarlal J, Aponte JJ et al. Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial. Lancet 366(9502), 2012-2018 (2005). • Demonstrates that a subunit malaria vaccine can induce some level of durable protection in a target population.
    • Alonso PL, Sacarlal J, Aponte JJ et al. Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial. Lancet 366(9502), 2012-2018 (2005). • Demonstrates that a subunit malaria vaccine can induce some level of durable protection in a target population.
  • 34
    • 5644228594 scopus 로고    scopus 로고
    • Alonso PL, Sacarlal J, Aponte JJ et al. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364(9443), 1411-1420 (2004). • The first report of clear and significant protection against clinical malaria in African children using the RTS,S/AS02A vaccine. Protection against both clinical disease and parasitaemia was observed that lasted several months.
    • Alonso PL, Sacarlal J, Aponte JJ et al. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364(9443), 1411-1420 (2004). • The first report of clear and significant protection against clinical malaria in African children using the RTS,S/AS02A vaccine. Protection against both clinical disease and parasitaemia was observed that lasted several months.
  • 35
    • 0037654736 scopus 로고    scopus 로고
    • Development of RTS,S/AS02: A purified subunit-based malaria vaccine candidate formulated with a novel adjuvant
    • Garcon N, Heppner DG, Cohen J. Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant. Expert Rev. Vaccines 2(2), 231-238 (2003).
    • (2003) Expert Rev. Vaccines , vol.2 , Issue.2 , pp. 231-238
    • Garcon, N.1    Heppner, D.G.2    Cohen, J.3
  • 36
    • 20044362219 scopus 로고    scopus 로고
    • Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: Progress at the Walter Reed Army Institute of Research
    • Heppner DG Jr, Kester KE, Ockenhouse CF et al. Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research. Vaccine 23(17-18), 2243-2250 (2005).
    • (2005) Vaccine , vol.23 , Issue.17-18 , pp. 2243-2250
    • Heppner Jr, D.G.1    Kester, K.E.2    Ockenhouse, C.F.3
  • 37
    • 0032745349 scopus 로고    scopus 로고
    • Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine
    • Lalvani A, Moris P, Voss G et al. Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine. J. Infect. Dis. 180(5), 1656-1664 (1999).
    • (1999) J. Infect. Dis , vol.180 , Issue.5 , pp. 1656-1664
    • Lalvani, A.1    Moris, P.2    Voss, G.3
  • 38
    • 11144353591 scopus 로고    scopus 로고
    • A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
    • Reece WH, Pinder M, Gothard PK et al. A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. Nat. Med. 10(4), 406-410 (2004).
    • (2004) Nat. Med , vol.10 , Issue.4 , pp. 406-410
    • Reece, W.H.1    Pinder, M.2    Gothard, P.K.3
  • 39
    • 33244471717 scopus 로고    scopus 로고
    • Pre-erythrocytic malaria vaccines: Towards greater efficacy
    • Hill AV. Pre-erythrocytic malaria vaccines: towards greater efficacy. Nat. Rev. Immunol. 6(1), 21-32 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , Issue.1 , pp. 21-32
    • Hill, A.V.1
  • 40
    • 0036892173 scopus 로고    scopus 로고
    • A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts
    • Birkett A, Lyons K, Schmidt A et al. A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts. Infect. Immun. 70(12), 6860-6870 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.12 , pp. 6860-6870
    • Birkett, A.1    Lyons, K.2    Schmidt, A.3
  • 41
    • 7044254906 scopus 로고    scopus 로고
    • Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes
    • Nardin EH, Oliveira GA, Calvo-Calle JM et al. Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes. Infect. Immun. 72(11), 6519-6527 (2004).
    • (2004) Infect. Immun , vol.72 , Issue.11 , pp. 6519-6527
    • Nardin, E.H.1    Oliveira, G.A.2    Calvo-Calle, J.M.3
  • 42
    • 21144480904 scopus 로고    scopus 로고
    • Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a Phase I trial
    • Oliveira GA, Wetzel K, Calvo-Calle JM et al. Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a Phase I trial. Infect. Immun. 73(6), 3587-3597 (2005).
    • (2005) Infect. Immun , vol.73 , Issue.6 , pp. 3587-3597
    • Oliveira, G.A.1    Wetzel, K.2    Calvo-Calle, J.M.3
  • 43
    • 10444286628 scopus 로고    scopus 로고
    • Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720
    • Walther M, Dunachie S, Keating S et al. Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720. Vaccine 23(7), 857-864 (2005).
    • (2005) Vaccine , vol.23 , Issue.7 , pp. 857-864
    • Walther, M.1    Dunachie, S.2    Keating, S.3
  • 44
    • 0034938975 scopus 로고    scopus 로고
    • A synthetic malaria vaccine elicits a potent CD8(+) and CD4(+) T lymphocyte immune response in humans. Implications for vaccination strategies
    • Lopez JA, Weilenman C, Audran R et al. A synthetic malaria vaccine elicits a potent CD8(+) and CD4(+) T lymphocyte immune response in humans. Implications for vaccination strategies. Eur. J. Immunol. 31(7), 1989-1998 (2001).
    • (2001) Eur. J. Immunol , vol.31 , Issue.7 , pp. 1989-1998
    • Lopez, J.A.1    Weilenman, C.2    Audran, R.3
  • 46
    • 23244456102 scopus 로고    scopus 로고
    • DNA vaccines: Progress and challenges
    • Donnelly JJ, Wahren B, Liu MA. DNA vaccines: progress and challenges. J. Immunol. 175(2), 633-639 (2005).
    • (2005) J. Immunol , vol.175 , Issue.2 , pp. 633-639
    • Donnelly, J.J.1    Wahren, B.2    Liu, M.A.3
  • 47
    • 0028130518 scopus 로고
    • Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines
    • Ulmer JB, Deck RR, DeWitt CM et al. Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines. Vaccine 12(16), 1541-1544 (1994).
    • (1994) Vaccine , vol.12 , Issue.16 , pp. 1541-1544
    • Ulmer, J.B.1    Deck, R.R.2    DeWitt, C.M.3
  • 48
    • 0027411456 scopus 로고
    • Heterologous protection against influenza by injection of DNA encoding a viral protein
    • Ulmer JB, Donnelly JJ, Parker SE et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259(5102), 1745-1749 (1993).
    • (1993) Science , vol.259 , Issue.5102 , pp. 1745-1749
    • Ulmer, J.B.1    Donnelly, J.J.2    Parker, S.E.3
  • 49
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • Wolff JA, Malone RW, Williams P et al. Direct gene transfer into mouse muscle in vivo. Science 247(4949 Pt 1), 1465-1468 (1990).
    • (1990) Science , vol.247 , Issue.4949 PART 1 , pp. 1465-1468
    • Wolff, J.A.1    Malone, R.W.2    Williams, P.3
  • 50
    • 0036132847 scopus 로고    scopus 로고
    • Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice
    • Moore AC, Kong WP, Chakrabarti BK, Nabel GJ. Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice. J. Virol. 76(1), 243-250 (2002).
    • (2002) J. Virol , vol.76 , Issue.1 , pp. 243-250
    • Moore, A.C.1    Kong, W.P.2    Chakrabarti, B.K.3    Nabel, G.J.4
  • 51
    • 0028077102 scopus 로고
    • Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein
    • Sedegah M, Hedstrom R, Hobart P, Hoffman SL. Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc. Natl Acad. Sci. USA 91(21), 9866-9870 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , Issue.21 , pp. 9866-9870
    • Sedegah, M.1    Hedstrom, R.2    Hobart, P.3    Hoffman, S.L.4
  • 52
    • 0344994574 scopus 로고    scopus 로고
    • Gene gun intradermal DNA immunization followed by boosting with modified vaccinia virus Ankara: Enhanced CD8+ T cell immunogenicity and protective efficacy in the influenza and malaria models
    • Degano P, Schneider J, Hannan CM, Gilbert SC, Hill AV. Gene gun intradermal DNA immunization followed by boosting with modified vaccinia virus Ankara: enhanced CD8+ T cell immunogenicity and protective efficacy in the influenza and malaria models. Vaccine 18(7-8), 623-632 (1999).
    • (1999) Vaccine , vol.18 , Issue.7-8 , pp. 623-632
    • Degano, P.1    Schneider, J.2    Hannan, C.M.3    Gilbert, S.C.4    Hill, A.V.5
  • 53
    • 0031573524 scopus 로고    scopus 로고
    • Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites
    • Leitner WW, Seguin MC, Ballou WR et al. Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites. J. Immunol. 159(12), 6112-6119 (1997).
    • (1997) J. Immunol , vol.159 , Issue.12 , pp. 6112-6119
    • Leitner, W.W.1    Seguin, M.C.2    Ballou, W.R.3
  • 54
    • 17444435761 scopus 로고    scopus 로고
    • Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients
    • Calarota S, Bratt G, Nordlund S et al. Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients. Lancet 351(9112), 1320-1325 (1998).
    • (1998) Lancet , vol.351 , Issue.9112 , pp. 1320-1325
    • Calarota, S.1    Bratt, G.2    Nordlund, S.3
  • 55
    • 0005457558 scopus 로고    scopus 로고
    • First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response
    • MacGregor RR, Boyer JD, Ugen KE et al. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. J. Infect. Dis. 178(1), 92-100 (1998).
    • (1998) J. Infect. Dis , vol.178 , Issue.1 , pp. 92-100
    • MacGregor, R.R.1    Boyer, J.D.2    Ugen, K.E.3
  • 56
    • 0032538597 scopus 로고    scopus 로고
    • Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
    • Wang R, Doolan DL, Le TP et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 282(5388), 476-480 (1998).
    • (1998) Science , vol.282 , Issue.5388 , pp. 476-480
    • Wang, R.1    Doolan, D.L.2    Le, T.P.3
  • 57
    • 0038714287 scopus 로고    scopus 로고
    • Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
    • McConkey SJ, Reece WH, Moorthy VS et al. Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nat. Med. 9(6), 729-735 (2003).
    • (2003) Nat. Med , vol.9 , Issue.6 , pp. 729-735
    • McConkey, S.J.1    Reece, W.H.2    Moorthy, V.S.3
  • 58
    • 10744224195 scopus 로고    scopus 로고
    • + T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus
    • + T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus. J. Immunol. 172(5), 3094-3100 (2004).
    • (2004) J. Immunol , vol.172 , Issue.5 , pp. 3094-3100
    • Anderson, R.J.1    Hannan, C.M.2    Gilbert, S.C.3
  • 59
    • 17344363385 scopus 로고    scopus 로고
    • Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a poxvectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria
    • Ockenhouse CF, Sun PF, Lanar DE et al. Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a poxvectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J. Infect. Dis. 177(6), 1664-1673 (1998).
    • (1998) J. Infect. Dis , vol.177 , Issue.6 , pp. 1664-1673
    • Ockenhouse, C.F.1    Sun, P.F.2    Lanar, D.E.3
  • 60
    • 0036310296 scopus 로고    scopus 로고
    • Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines
    • Amara RR, Villinger F, Staprans SI et al. Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines. J. Virol. 76(15), 7625-7631 (2002).
    • (2002) J. Virol , vol.76 , Issue.15 , pp. 7625-7631
    • Amara, R.R.1    Villinger, F.2    Staprans, S.I.3
  • 61
    • 27144489392 scopus 로고    scopus 로고
    • Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria
    • Keating SM, Bejon P, Berthoud T et al. Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria. J. Immunol. 175(9), 5675-5680 (2005).
    • (2005) J. Immunol , vol.175 , Issue.9 , pp. 5675-5680
    • Keating, S.M.1    Bejon, P.2    Berthoud, T.3
  • 62
    • 3142670662 scopus 로고    scopus 로고
    • Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys
    • Letvin NL, Huang Y, Chakrabarti BK et al. Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. J. Virol. 78(14), 7490-7497 (2004).
    • (2004) J. Virol , vol.78 , Issue.14 , pp. 7490-7497
    • Letvin, N.L.1    Huang, Y.2    Chakrabarti, B.K.3
  • 63
    • 0036181979 scopus 로고    scopus 로고
    • Protective immunity against Mycobacterium tuberculosis induced by dendritic cells pulsed with both CD8(+)- and CD4(+)-T-cell epitopes from antigen 85A
    • McShane H, Behboudi S, Goonetilleke N, Brookes R, Hill AV. Protective immunity against Mycobacterium tuberculosis induced by dendritic cells pulsed with both CD8(+)- and CD4(+)-T-cell epitopes from antigen 85A. Infect. Immun. 70(3), 1623-1626 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.3 , pp. 1623-1626
    • McShane, H.1    Behboudi, S.2    Goonetilleke, N.3    Brookes, R.4    Hill, A.V.5
  • 64
    • 2942624113 scopus 로고    scopus 로고
    • Phase I evaluation of 3 highly immunogenic prime-boost regimens, including a 12-month reboosting vaccination, for malaria vaccination in Gambian men
    • Moorthy VS, Imoukhuede EB, Keating S et al. Phase I evaluation of 3 highly immunogenic prime-boost regimens, including a 12-month reboosting vaccination, for malaria vaccination in Gambian men. J. Infect. Dis. 189(12), 2213-2219 (2004).
    • (2004) J. Infect. Dis , vol.189 , Issue.12 , pp. 2213-2219
    • Moorthy, V.S.1    Imoukhuede, E.B.2    Keating, S.3
  • 65
    • 0242364645 scopus 로고    scopus 로고
    • Safety and immunogenicity of DNA/modified vaccinia virus ankara malaria vaccination in African adults
    • Moorthy VS, Pinder M, Reece WH et al. Safety and immunogenicity of DNA/modified vaccinia virus ankara malaria vaccination in African adults. J. Infect. Dis. 188(8), 1239-1244 (2003).
    • (2003) J. Infect. Dis , vol.188 , Issue.8 , pp. 1239-1244
    • Moorthy, V.S.1    Pinder, M.2    Reece, W.H.3
  • 66
    • 10844264174 scopus 로고    scopus 로고
    • Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers
    • Vuola JM, Keating S, Webster DP et al. Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers. J. Immunol. 174(1), 449-455 (2005).
    • (2005) J. Immunol , vol.174 , Issue.1 , pp. 449-455
    • Vuola, J.M.1    Keating, S.2    Webster, D.P.3
  • 67
    • 0042739176 scopus 로고    scopus 로고
    • Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates
    • Sullivan NJ, Geisbert TW, Geisbert JB et al. Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature 424(6949), 681-684 (2003).
    • (2003) Nature , vol.424 , Issue.6949 , pp. 681-684
    • Sullivan, N.J.1    Geisbert, T.W.2    Geisbert, J.B.3
  • 68
    • 33644913115 scopus 로고    scopus 로고
    • A clinical trial of immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS
    • Dunachie SJ, Walther M, Vuola JM et al. A clinical trial of immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS. Vaccine 24(15), 2850-2859 (2006).
    • (2006) Vaccine , vol.24 , Issue.15 , pp. 2850-2859
    • Dunachie, S.J.1    Walther, M.2    Vuola, J.M.3
  • 69
    • 0035919607 scopus 로고    scopus 로고
    • Modulation of the antibody response to the HIV envelope subunit by co-administration of infectious or heat-inactivated canarypoxvirus (ALVAC) preparations
    • Boudet F, Chevalier M, Jourdier TM, Tartaglia J, Moste C. Modulation of the antibody response to the HIV envelope subunit by co-administration of infectious or heat-inactivated canarypoxvirus (ALVAC) preparations. Vaccine 19(30), 4267-4275 (2001).
    • (2001) Vaccine , vol.19 , Issue.30 , pp. 4267-4275
    • Boudet, F.1    Chevalier, M.2    Jourdier, T.M.3    Tartaglia, J.4    Moste, C.5
  • 70
    • 0037309097 scopus 로고    scopus 로고
    • Induction of humoral and cell-mediated immunity to hepatitis B surface antigen by a novel adjuvant activity of Oka varicella vaccine
    • Phumiamorn S, Sato H, Kamiyama T, Kurokawa M, Shiraki K. Induction of humoral and cell-mediated immunity to hepatitis B surface antigen by a novel adjuvant activity of Oka varicella vaccine. J. Gen. Virol. 84(Pt 2), 287-291 (2003).
    • (2003) J. Gen. Virol , vol.84 , Issue.PART 2 , pp. 287-291
    • Phumiamorn, S.1    Sato, H.2    Kamiyama, T.3    Kurokawa, M.4    Shiraki, K.5
  • 71
    • 0342470981 scopus 로고    scopus 로고
    • Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: Virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine
    • Ramirez JC, Gherardi MM, Esteban M. Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine. J. Virol. 74(2), 923-933 (2000).
    • (2000) J. Virol , vol.74 , Issue.2 , pp. 923-933
    • Ramirez, J.C.1    Gherardi, M.M.2    Esteban, M.3
  • 72
    • 0042591464 scopus 로고    scopus 로고
    • Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
    • Cassese G, Arce S, Hauser AE et al. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 171(4), 1684-1690 (2003).
    • (2003) J. Immunol , vol.171 , Issue.4 , pp. 1684-1690
    • Cassese, G.1    Arce, S.2    Hauser, A.E.3
  • 74
    • 0041439934 scopus 로고    scopus 로고
    • Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens
    • Moore T, Ekworomadu CO, Eko FO et al. Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens. J. Infect. Dis. 188(4), 617-624 (2003).
    • (2003) J. Infect. Dis , vol.188 , Issue.4 , pp. 617-624
    • Moore, T.1    Ekworomadu, C.O.2    Eko, F.O.3
  • 75
    • 0031114121 scopus 로고    scopus 로고
    • Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor Fc γ RI (CD64) expressed on human blood dendritic cells
    • Fanger NA, Voigtlaender D, Liu C et al. Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor Fc γ RI (CD64) expressed on human blood dendritic cells. J. Immunol. 158(7), 3090-3098 (1997).
    • (1997) J. Immunol , vol.158 , Issue.7 , pp. 3090-3098
    • Fanger, N.A.1    Voigtlaender, D.2    Liu, C.3
  • 76
    • 0035164465 scopus 로고    scopus 로고
    • A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes
    • Geissmann F, Launay P, Pasquier B et al. A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes. J. Immunol. 166(1), 346-352 (2001).
    • (2001) J. Immunol , vol.166 , Issue.1 , pp. 346-352
    • Geissmann, F.1    Launay, P.2    Pasquier, B.3
  • 77
    • 0026445735 scopus 로고
    • Enhanced antigen presentation using human Fc γ receptor (monocyte/macrophage)-specific immunogens
    • Gosselin EJ, Wardwell K, Gosselin DR et al. Enhanced antigen presentation using human Fc γ receptor (monocyte/macrophage)-specific immunogens. J. Immunol. 149(11), 3477-3481 (1992).
    • (1992) J. Immunol , vol.149 , Issue.11 , pp. 3477-3481
    • Gosselin, E.J.1    Wardwell, K.2    Gosselin, D.R.3
  • 78
    • 0033579698 scopus 로고    scopus 로고
    • Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization
    • Regnault A, Lankar D, Lacabanne V et al. Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J. Exp. Med. 189(2), 371-380 (1999).
    • (1999) J. Exp. Med , vol.189 , Issue.2 , pp. 371-380
    • Regnault, A.1    Lankar, D.2    Lacabanne, V.3
  • 79
    • 0034974006 scopus 로고    scopus 로고
    • Immunity to Bordetella pertussis
    • Mills KH. Immunity to Bordetella pertussis. Microbes Infect. 3(8), 655-677 (2001).
    • (2001) Microbes Infect , vol.3 , Issue.8 , pp. 655-677
    • Mills, K.H.1
  • 81
    • 33644971704 scopus 로고    scopus 로고
    • Polylactide-co-glycolide microparticles with surface adsorbed antigens as vaccine delivery systems
    • Singh M, Kazzaz J, Ugozzoli M et al. Polylactide-co-glycolide microparticles with surface adsorbed antigens as vaccine delivery systems. Curr. Drug Deliv. 3(1), 115-120 (2006).
    • (2006) Curr. Drug Deliv , vol.3 , Issue.1 , pp. 115-120
    • Singh, M.1    Kazzaz, J.2    Ugozzoli, M.3
  • 82
    • 28044447431 scopus 로고    scopus 로고
    • Peptides delivered by immunostimulating reconstituted influenza virosomes
    • Westerfeld N, Zurbriggen R. Peptides delivered by immunostimulating reconstituted influenza virosomes. J. Pept. Sci. 11(11), 707-712 (2005).
    • (2005) J. Pept. Sci , vol.11 , Issue.11 , pp. 707-712
    • Westerfeld, N.1    Zurbriggen, R.2
  • 83
    • 0033195259 scopus 로고    scopus 로고
    • Historical review of smallpox, the eradication of smallpox and the attenuated smallpox MVA vaccine]
    • Mayr A. [Historical review of smallpox, the eradication of smallpox and the attenuated smallpox MVA vaccine]. Berl. Munch. Tierarztl. Wochenschr. 112(9), 322-328 (1999).
    • (1999) Berl. Munch. Tierarztl. Wochenschr , vol.112 , Issue.9 , pp. 322-328
    • Mayr, A.1
  • 84
    • 0029957222 scopus 로고    scopus 로고
    • Applications of pox virus vectors to vaccination: An update
    • Paoletti E. Applications of pox virus vectors to vaccination: an update. Proc. Natl Acad. Sci. USA 93(21), 11349-11353 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.21 , pp. 11349-11353
    • Paoletti, E.1
  • 85
    • 0037081381 scopus 로고    scopus 로고
    • Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes
    • Gilbert SC, Schneider J, Hannan CM et al. Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. Vaccine 20(7-8), 1039-1045 (2002).
    • (2002) Vaccine , vol.20 , Issue.7-8 , pp. 1039-1045
    • Gilbert, S.C.1    Schneider, J.2    Hannan, C.M.3
  • 86
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • Tatsis N, Ertl HC. Adenoviruses as vaccine vectors. Mol. Ther. 10(4), 616-629 (2004).
    • (2004) Mol. Ther , vol.10 , Issue.4 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 87
    • 17944369697 scopus 로고    scopus 로고
    • A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees
    • Schneider J, Langermans JA, Gilbert SC et al. A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees. Vaccine 19(32), 4595-4602 (2001).
    • (2001) Vaccine , vol.19 , Issue.32 , pp. 4595-4602
    • Schneider, J.1    Langermans, J.A.2    Gilbert, S.C.3
  • 88
    • 9144267735 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans
    • McShane H, Pathan AA, Sander CR et al. Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nat. Med. 10(11), 1240-1244 (2004).
    • (2004) Nat. Med , vol.10 , Issue.11 , pp. 1240-1244
    • McShane, H.1    Pathan, A.A.2    Sander, C.R.3
  • 89
    • 0034735774 scopus 로고    scopus 로고
    • Development of a preventive vaccine for Ebola virus infection in primates
    • Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature 408(6812), 605-609 (2000).
    • (2000) Nature , vol.408 , Issue.6812 , pp. 605-609
    • Sullivan, N.J.1    Sanchez, A.2    Rollin, P.E.3    Yang, Z.Y.4    Nabel, G.J.5


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