Quantitative fluorescein angiographic analysis of choroidal neovascular membranes: Validation and correlation with visual function

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 1, 2007, Pages 349-354

  Chakravarthy, Usha ^a,b   Walsh, Alexander C ^a   Muldrew, Alyson ^b   Updike, Paul G ^a   Barbour, Tara ^a   Sadda, SriniVas R ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c Doheny Retina Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMPUTER ANALYSIS; FLUORESCENCE ANGIOGRAPHY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; OPTIC NERVE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION; VALIDATION PROCESS; VISION; VISUAL ACUITY; COMPARATIVE STUDY; IMAGE PROCESSING; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA MACULA DEGENERATION;

CHOROIDAL NEOVASCULARIZATION; FLUORESCEIN ANGIOGRAPHY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MACULAR DEGENERATION; VISUAL ACUITY;

EID: 33846909070     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0493     Document Type: Article

References (16)

1. Macular Photocoagulation Study Group. Subfoveal neovascular lesions in age-related macular degeneration: guidelines for evaluation and treatment in the macular photocoagulation study. Arch Ophthalmol. 1991;109:1242-1257.
2. Hogg R, Curry E, Muldrew A, et al. Identification of lesion components that influence visual function in age related macular degeneration. Br J Ophthalmol. 2003;87:609-614.
3. Jaakkola A, Tommila P, Laatikainen L, Immonen I. Grading choroidal neovascular membrane regression after strontium plaque radiotherapy: masked subjective evaluation vs. planimetry. Eur J Ophthalmol. 2001;11:269-276.
4. Kaiser RS, Berger JW, Williams GA, et al. Variability in fluorescein angiography interpretation for photodynamic therapy in age-related macular degeneration. Retina. 2002;22:683-690.
5. Doris N, Hart PM, Chakravarthy U, et al. Relation between macular morphology and visual function in patients with choroidal neovascularisation of age related macular degeneration. Br J Ophthalmol. 2001;85:184-188.
6. Berger JW, Yoken J. Computer-assisted quantitation of choroidal neovascularization for clinical trials. Invest Ophthalmol Vis Sci. 2000;41:2286-2295.
7. Hipwell JH, Manivannan A, Vieira P, et al. Quantifying changes in retinal circulation: the generation of parametric images from fluorescein angiograms. Physiol Meas. 1998;19:165-180.
8. Gragoudas ES, Adamis AP, Cunningham ET Jr, et al. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med. 2004;351:2805-2816.
9. Gonzales CR. Enhanced efficacy associated with early treatment of neovascular age-related macular degeneration with pegaptanib sodium: an exploratory analysis. Retina. 2005;25:815-827.
10. Kourlas H, Schiller DS. Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review. Clin Ther. 2006;28:36-44.
11. Saito J, Roxburgh ST, Sutton D, Ellingford A. A new method of image analysis of fluorescein angiography applied to age-related macular degeneration. Eye. 1995;9:70-6.
12. Hart PM, Chakravarthy U, Mackenzie G, et al. Visual outcomes in the subfoveal radiotherapy study: a randomized controlled trial of teletherapy for age-related macular degeneration. Arch Ophthalmol. 2002;120:1029-1038.
13. Solomon SD, Bressler SB, Hawkins BS, et al. Guidelines for interpreting retinal photographs and coding findings in the Submacular Surgery Trials (SST): SST report no. 8. Retina. 2005;25:253-268.
14. Sadda SR, Pieramici DJ, Marsh MJ, et al. Changes in lesion size after submacular surgery for subfoveal choroidal neovascularization in the submacuiar surgery trials pilot study. Retina. 2004;24:888-899.
15. TAP Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials-TAP report: treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol. 1999;117:1329-1345.
16. Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration: updated findings from two clinical trials. Arch Ophthalmol. 1993;111:1200-1209.