Modeling cardiac activation and the impact of a discontinuous myocardium

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 7 VOLS, Issue , 2005, Pages 341-344

  Trew, Mark ^a   Sands, Gregory ^a   Caldwell, Bryan ^b   Hooks, Darren ^a   LeGrice, Ian ^a,b   Smaill, Bruce ^a,b   Pullan, Andrew ^a,b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Activation; Bidomain; Cardiac; Microstructure; Modeling

Indexed keywords

BIOELECTRIC POTENTIALS; COMPUTATIONAL METHODS; COMPUTER SIMULATION; MICROSTRUCTURE; TISSUE;

CARDIAC ACTIVATION; MYOCARDIAL CURRENT FLOW; MYOCARDIUM;

CARDIOVASCULAR SYSTEM;

EID: 33846898777     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/iembs.2005.1616414     Document Type: Conference Paper

References (14)

1. I. LeGrice, B. Smaill, L. Chai, S. Edgar, J. Gavin and P. Hunter, "Laminar structure of the heart: ventricular myocyte arrangement and connective tissue architecture in the dog," American Journal of Physiology, vol. 269, pp. H571-H582, 1995.
2. M. Spach and P. Dolber, "Relating Extracellular Potentials and Their Derivatives to Anisotropic Propagation at the Microscopic Level in Human Cardiac Muscle," Circulation Research, vol. 58, no. 3, pp. 356-371, 1996.
3. O.F. Sharifov and V.G. Fast, "Optical Mapping of Transmural Activation Induced by Electrical Shocks in Isolated Left Ventricular Wall Wedge Preparations," Journal of Cardiovascular Electrophysiology, vol. 14, no. 11, pp. 1215-1222, 2003.
4. D. Hooks, K. Tomlinson, S. Marsden, I. LeGrice, B. Smaill, A. Pullan and P. Hunter, "Cardiac Microstructure: Implications for Electrical Propagation and Defibrillation in the Heart," Circulation Research, vol. 91, no. 4, pp. 331-338, Aug. 2002.
5. M. Trew, I. LeGrice, A. Pullan and B. Smaill, "The Role of Cardiac Microstructure In Tissue Excitation Propagation," presented at the World Congress on Medical Physics and Biomedical Engineering, Sydney, Australia, 2003.
6. G. Sands, M. Trew, D. Hooks, I. LeGrice, A. Pullan and B. Smaill, "Constructing a Tissue-Specific Model of Ventricular Microstructure," in Proc. 26th Ann. Int. Conf. IEEE EMBS, San Francisco, CA, pp. 3589-3592, Sep. 2004.
7. M. Trew, I. LeGrice, B. Smaill and A. Pullan, "A Finite Volume Method for Modeling Discontinuous Electrical Activation in Cardiac Tissue," Annals of Biomedical Engineering, vol. 33, no. 5, May, 2005.
8. M. Trew and G. Sands, "Shock-Induced Transmembrane Potential Fields in a Model of Cardiac Microstructure," Journal of Cardiovascular Electrophysiology, vol. 16, August, 2005.
9. B. Caldwell, M. Trew, I. LeGrice, D. Hooks, A. Pullan and B. Smaill, "Fractionation of electrograms but not transmembrane potentials adjacent to intramural stimulus: Nonuniform electrical activation due to discontinuous myocardial architecture?" unpublished.
10. D. Hooks, M. Trew, B. Smaill and A. Pullan "Evidence that Intramural Virtual Electrodes Facilitate Successful Defibrillation. Model Based Analysis of Experimental Evidence.," unpublished.
11. G. Sands, D. Gerneke, D. Hooks, C. Green, B. Smaill and I. LeGrice, "Automated Imaging of Extended Tissue Volumes using Confocal Microscopy," unpublished.
12. A. Young, I. LeGrice, M. Young and B. Smaill, "Extended confocal microscopy of myocardial laminae and collagen network," Journal of Microscopy, vol. 192, no. 2, pp. 139-150, Nov. 1998.
13. M. Buist, G. Sands, P. Hunter and A. Pullan, "A deformable finite element derived finite difference method for cardiac activation problems", Annals of Biomedical Engineering, vol. 31, pp. 577-588, 2003.
14. T. Austin, M. Trew and A. Pullan, "A Comparison of Multilevel Solvers for the Cardiac Bidomain Equations," unpublished.