Improvement of sordarin production through process optimization: Combining traditional approaches with DOE

Journal of Industrial Microbiology and Biotechnology

Volumn 34, Issue 3, 2007, Pages 193-202

  Tully, Thomas P ^a   Bergum, James S ^a   Schwarz, Steven R ^a   Durand, Susan C ^a   Howell, Jeffrey M ^a   Patel, Ramesh N ^a   Cino, Paul M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Central composite design; Factorial design; Fermentation optimization; Sordaria araneosa; Sordarin

Indexed keywords

SORDARIN;

ARTICLE; ASPERGILLUS; BIOLOGICAL ACTIVITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG STRUCTURE; FERMENTATION; NONHUMAN;

FERMENTATION; INDENES; RESEARCH DESIGN; SORDARIALES;

ASPERGILLUS; FUNGI; SORDARIA;

EID: 33846890370     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-006-0186-0     Document Type: Article

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