Oxidative stress injury during cardiac surgery: How important is it?

Cardiovascular Research

Volumn 73, Issue 4, 2007, Pages 626-628

  Chambers, David J ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; CREATINE KINASE MB; CREATININE; GLUTATHIONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROPONIN T;

CARDIOPLEGIA; CORONARY ARTERY BYPASS GRAFT; EDITORIAL; HEART EJECTION FRACTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART SURGERY; HEART VENTRICLE FUNCTION; HUMAN; ISCHEMIC PRECONDITIONING; LIPID PEROXIDATION; NONHUMAN; OFF PUMP CORONARY SURGERY; OXIDATIVE STRESS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; STUNNED HEART MUSCLE;

ANIMALS; ANTIOXIDANTS; CORONARY ARTERY BYPASS; HUMANS; INTRAOPERATIVE PERIOD; LIPID PEROXIDATION; MODELS, ANIMAL; MYOCARDIAL ISCHEMIA; MYOCARDIUM; OXIDATIVE STRESS;

EID: 33846873468     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2007.01.007     Document Type: Editorial

References (15)

1. Hearse D.J., Humphrey S.M., and Bullock G.R. The oxygen paradox and the calcium paradox: two facets of the same problem?. J Mol Cell Cardiol 10 (1978) 641-668
2. Dhalla N.S., Elmoselhi A.B., Hata T., and Makino N. Status of myocardial antioxidants in ischemia-reperfusion injury. Cardiovasc Res 47 (2000) 446-456
3. Garlick P.B., Davies M.J., Hearse D.J., and Slater T.F. Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circ Res 61 (1987) 757-760
4. Shuter S.L., Davies M.J., Garlick P.B., Hearse D.J., and Slater T.F. Studies on the effects of antioxidants and inhibitors of radical generation on free radical production in the reperfused rat heart using electron spin resonance spectroscopy. Free Radic Res Commun 9 (1990) 223-232
5. Chambers D.J., Braimbridge M.V., and Hearse D.J. Free radicals and cardioplegia: allopurinol and oxypurinol reduce myocardial injury following ischemic arrest. Ann Thorac Surg 44 (1987) 291-297
6. Chambers D.J., Braimbridge M.V., and Hearse D.J. Free radicals and cardioplegia. Free radical scavengers improve postischemic function of rat myocardium. Eur J Cardio-thorac Surg 1 (1987) 37-45
7. Bolli R., Jeroudi M.O., Patel B.S., Aruoma O.I., Halliwell B., Lai E.K., et al. Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury. Circ Res 65 (1989) 607-622
8. Breisblatt W.M., Stein K.L., Wolfe C.J., Follansbee W.P., Capozzi J., Armitage J.M., et al. Acute myocardial dysfunction and recovery: a common occurrence after coronary bypass surgery. J Am Coll Cardiol 15 (1990) 1261-1269
9. Kato R., and Foex P. Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Can J Anaesth 49 (2002) 777-791
10. Zaugg M., Lucchinetti E., Spahn D.R., Pasch T., Garcia C., and Schaub M.C. Differential effects of anesthetics on mitochondrial K(ATP) channel activity and cardiomyocyte protection. Anesthesiology 97 (2002) 15-23
11. Milei J., Forcada P., Fraga C.G., Grana D.R., Iannelli G., Chiarello M., et al. Relationship between oxidative stress, lipid peroxidation, and ultrastructural damage in patients with coronary artery disease undergoing cardioplegic arrest/reperfusion. Cardiovasc Res 73 (2007) 710-719
12. El-Hamamsy I., Stevens L.M., Carrier M., Pellerin M., Bouchard D., Demers P., et al. Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trial. J Thorac Cardiovasc Surg 133 (2007) 7-12
13. Tossios P., Bloch W., Huebner A., Raji M.R., Dodos F., Klass O., et al. N-acetylcysteine prevents reactive oxygen species-mediated myocardial stress in patients undergoing cardiac surgery: results of a randomized, double-blind, placebo-controlled clinical trial. J Thorac Cardiovasc Surg 126 (2003) 1513-1520
14. Lassnigg A., Punz A., Barker R., Keznickl P., Manhart N., Roth E., et al. Influence of intravenous vitamin E supplementation in cardiac surgery on oxidative stress: a double-blinded, randomized, controlled study. Br J Anaesth 90 (2003) 148-154
15. Akila, D'Souza B., Vishwanath P., and D'Souza V. Oxidative injury and antioxidants in coronary artery bypass graft surgery: off-pump CABG significantly reduces oxidative stress. Clin Chim Acta 375 (2007) 147-152