Metabolism and bioactivation of 3-methylindole by human liver microsomes

Chemical Research in Toxicology

Volumn 20, Issue 1, 2007, Pages 140-148

  Yan, Zhengyin ^a   Easterwood, LaHoma M ^a   Maher, Noureddine ^a   Torres, Rhoda ^a   Huebert, Norman ^a   Yost, Garold S ^b  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 GLUTATHIONYL 3 METHYLOXINDOLE; 2,3 EPOXIDE 3 METHYLINDOLE; 3 GLUTATHIONYL 3 METHYLOXINDOLE; 3 GLUTATHIONYLMETHYLINDOLE; 3 HYDROXY 3 METHYLINDOLENINE; 3 HYDROXY 3 METHYLOXINDOLE; 3 METHYLENENINDOLENINE; 3 METHYLOXINDOLE; 4 HYDROXY 3 METHYLINDOLE; 5 GLUTATHIONYL 3 METHYLOXINDOLE; 5 HYDROXY 3 METHYLINDOLE; 5,6 EPOXIDE; 6 GLUTATHIONYL 3 METHYLOXINDOLE; 6 HYDROXY 3 METHYLINDOLE; 7 HYDROXY METHYLINDOLE; CYTOCHROME P450 2E1; DEUTERIUM; EPOXIDE; GLUTATHIONE; INDOLE DERIVATIVE; SKATOLE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONJUGATION; CONTROLLED STUDY; DEHYDROGENATION; EPOXIDATION; HUMAN; HUMAN CELL; LIVER MICROSOME; OXIDATION; TOXICOKINETICS;

BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUTATHIONE; HUMANS; MASS SPECTROMETRY; MICROSOMES, LIVER; SKATOLE;

EID: 33846863767     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx060239e     Document Type: Article

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