Asynchronism of thymocyte development in vivo and in vitro

DNA and Cell Biology

Volumn 26, Issue 1, 2007, Pages 19-27

  Zhang, Jinping ^c   Gong, Yanping ^c   Shao, Xian'an ^c   Zhang, Ruihua ^c   Xu, Wei ^c   Chu, Yiwei ^c   Wang, Ying ^c   Xiong, Sidong ^a,b  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Institute of Pharmaceutical Industry   (China)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; FAS LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL MATURATION; CELL SYNCHRONIZATION; CELL VIABILITY; EMBRYO DEVELOPMENT; EVALUATION; FETAL THYMUS ORGAN CULTURE; FETUS; FLUORESCENCE ACTIVATED CELL SORTING; GESTATIONAL AGE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; ORGAN CULTURE TECHNIQUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; ANTIGENS, CD; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EMBRYO; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; ORGAN CULTURE TECHNIQUES; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; THYMUS GLAND;

MUS;

EID: 33846852223     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2006.0525     Document Type: Article

References (50)

1. ANDERSON, G., and JENKINSON, E.J. (2000). Review article: Thymus organ cultures and T-cell receptor repertoire development. Immunology 100, 405-410.
2. ASHTON-RICKARDT, P.G., BANDEIRA, A., DELANEY, J.R., VAN KAER, L., PIRCHER, H.P., ZINKERNAGEL, R.M., et al. (1994). Evidence for a differential avidity model of T cell selection in the thymus. Cell 76, 651-663.
3. AUERBACH, R. (1960). Morphogenetic interactions in the development of the mouse thymus gland. Dev. Biol. 2, 271-284.
4. BENOIST, C., and MATHIS, D. (1997). Positive selection of T cells: Fastidious or promiscuous? Curr. Opin. Immunol. 9, 245-249.
5. CARDARELLI, P.M., CRISPE, I.N., and PIERSCHBACHER, M.D. (1988). Preferential expression of fibronectin receptors on immature thymocytes. J. Cell Biol. 106, 2183-2190.
6. CARTER, J.D., CALABRESE, G.M., NAGANUMA, M., and LORENZ, U. (2005). Deficiency of the Src homology region 2 domain-containing phosphatase 1 (SHP-1) causes enrichment of CD4+CD25+ regulatory T cells. J. Immunol. 174, 6627-6638.
7. CEREDIG, R., MACDONALD, H.R., and JENKINSON, E.J. (1983). Flow microfluorometric analysis of mouse thymus development in vivo and in vitro. Eur. J. Immunol. 13, 185-190.
8. CONROY, L.A., BYTH, K.F., HOWLETT, S., HOLMES, N., and ALEXANDER, D.R. (1996). Defective depletion of CD45-null thymocytes by the Staphylococcus aureus enterotoxin B superantigen. Immunol. Lett. 54, 119-122.
9. DELUCA, D., BLUESTONE, J.A., SHULTZ, L.D., SHARROW, S.O., and TATSUMI, Y. (1995). Programmed differentiation of murine thymocytes during fetal thymus organ culture. J. Immunol. Methods. 178, 13-29.
10. DE SMEDT, M., HOEBEKE, I., REYNVOET, K., LECLERCQ, G., and PLUM, J. (2005). Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment. Blood 106, 3498-3506.
11. EICHHORST, S.T., MUERKOSTER, S., WEIGAND, M.A., and KRAMMER, P.H. (2001). The chemotherapeutic drug 5-fluorouracil induces apoptosis in mouse thymocytes in vivo via activation of the CD95(APO-1/Fas) system. Cancer Res. 61, 243-248.
12. FENG, C., WOODSIDE, K.J., VANCE, B.A., EL-KHOURY, D., CANELLES, M., LEE, J., et al. (2002). A potential role for CD69 in thymocyte emigration. Int. Immunol. 14, 535-544.
13. FINE, J.S., and KRUISBEEK, A.M. (1991). The role of LFA-1/ICAM-1 interactions during murine T lymphocyte development. J. Immunol. 147, 2852-2859.
14. FINKEL, T.H., CAMBIER, J.C., KUBO, R.T., BORN, W.K., MARRACK, P., and KAPPLER, J.W. (1989). The thymus has two functionally distinct populations of immature alpha beta + T cells: One population is deleted by ligation of alpha betaTCR. Cell 58, 1047-1054.
15. GRAY, D.H., UENO, T., CHIDGEY, A.P., MALIN, M., GOLDBERG, G.L., TAKAHAMA, Y., et al. (2005). Controlling the thymic microenvironment. Curr. Opin. Immunol. 17, 137-143.
16. HARE, K.J., JENKINSON, E.J., and ANDERSON, G. (1999). In vitro models of T cell development. Semin. Immunol. 11, 3-12.
17. HERNANDEZ-LOPEZ, C., VARAS, A., SACEDON, R., JIMENEZ, E., MUNOZ, J.J., ZAPATA, A.G., et al. (2002). Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development. Blood 99, 546-554.
18. HOGQUIST, K.A., JAMESON, S.C., HEATH, W.R., HOWARD, J.L., BEVAN, M.J., and CARBONE, F.R. (1994). T cell receptor antagonist peptides induce positive selection. Cell 76, 17-27.
19. HUNIG, T., TORRES-NAGEL, N., MEHLING, B., PARK, H.J., and HERRMANN, T. (2001). Thymic development and repertoire selection: The rat perspective. Immunol. Rev. 184, 7-19.
20. JENKINSON, E.J., KINGSTON, R., and OWEN, J.J. (1987). Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors. Nature 329, 160-162.
21. JENKINSON, E.J., ANDERSON, G., and OWEN, J.J. (1992). Studies on T cell maturation on defined thymic stromal cell populations in vitro. J. Exp. Med. 176, 845-853.
22. KIM, M.G., LEE, G., LEE, S.K., LOLKEMA, M., YIM, J., HONG, S.H., et al. (2000). Epithelial cell-specific laminin 5 is required for survival of early thymocytes. J. Immunol. 165, 192-201.
23. KISHIMOTO, H., SURH, C.D., and SPRENT, J. (1995). Upregulation of surface markers on dying thymocytes. J. Exp. Med. 181, 649-655.
24. KISIELOW, P., LEISERSON, W., and VON BOEHMER, H. (1984). Differentiation of thymocytes in fetal organ culture: Analysis of phenotypic changes accompanying the appearance of cytolytic and interleukin 2-producing cells. J. Immunol. 133, 1117-1123.
25. KURASAWA, K., HASHIMOTO, Y., and IWAMOTO, I. (1999). Fas modulates both positive and negative selection of thymocytes. Cell Immunol. 194, 127-135.
26. KWON, H., JUN, H.S., KHIL, L.Y., and YOON, J.W. (2004). Role of CTLA-4 in the activation of single- and double-positive thymocytes. J. Immunol. 173, 6645-6653.
27. LEVELT, C.N., CARSETTI, R., and EICHMANN, K. (1993). Regulation of thymocyte development through CD3. II. Expression of T cell receptor betaCD3epsilon and maturation of CD4+8+ stage are highly correlated in individual thymocytes. J. Exp. Med. 178, 1867-1875.
28. LUNDBERG, K., and SHORTMAN, K. (1994). Small cortical thymocytes are subject to positive selection. J. Exp. Med. 179, 1475-1483.
29. MANDEL, T.E., and KENNEDY, M.M. (1978). The differentiation of murine thymocytes in vivo and in vitro. Immunology 35, 317-331.
30. MATIBA, B., MARIANI, S.M., and KRAMMER, P.H. (1997). The CD95 system and the death of a lymphocyte. Semin. Immunol. 9, 59-68.
31. MOSIER, D.E., and PIERCE, C.W. (1972). Functional maturation of thymic lymphocyte populations in vitro. J. Exp. Med. 136, 1484-1500.
32. MULLER, K.P., MARIANI, S.M., MATIBA, B., KYEWSKI, B., and KRAMMER, P.H. (1995). Clonal deletion of major histocompatibility complex class I-restricted CD4+CD8+ thymocytes in vitro is independent of the CD95 (APO-1/Fas) ligand. Eur. J. Immunol. 25, 2996-2999.
33. NAKAYAMA, T., KASPROWICZ, D.J., YAMASHITA, M., SCHUBERT, L.A., GILLARD, G., KIMURA, M., et al. (2002). The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J. Immunol. 168, 87-94.
34. NISHIMURA, Y., ISHII, A., KOBAYASHI, Y., YAMASAKI, Y., and YONEHARA, S. (1995). Expression and function of mouse Fas antigen on immature and mature T cells. J. Immunol. 154, 4395-4403.
35. OGASAWARA, J., SUDA, T., and NAGATA, S. (1995). Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody. J. Exp. Med. 181, 485-491.
36. OHL, L., BERNHARDT, G., PABST, O., and FORSTER, R. (2003). Chemokines as organizers of primary and secondary lymphoid organs. Semin. Immunol. 15, 249-255.
37. ORGAN, E.L., NALBANTYAN, C.D., NANNEY, L.B., WOODWARD, S.C., SHENG, J., DUBOIS, R.N., et al. (2004). Effects of Transforming Growth Factor-alpha (TGF-alpha) in vitro and in vivo on reovirus replication. DNA Cell Biol. 23, 430-441.
38. PETRIE, H.T. (2003). Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus. Nat. Rev. Immunol. 3, 859-866.
39. PLUM, J., KONING, F., LECLERCQ, G., TISON, B., and DE SMEDT, M. (1990). Expansion of large granular lymphocytes in IL-2-driven 14-day-old fetal thymocytes in organ culture. J. Immunol. 144, 3710-3717.
40. PLUM, J., DE SMEDT, M., and LECLERCQ, G. (1993). Exogenous IL-7 promotes the growth of CD3-CD4-CD8-CD44+CD25+/- precursor cells and blocks the differentiation pathway of TCR-alpha beta cells in fetal thymus organ culture. J. Immunol. 150, 2706-2716.
41. PLUM, J., DE SMEDT, M., VERHASSELT, B., KERRE, T., VANHECKE, D., VANDEKERCKHOVE, B., et al. (2000). Human T lymphopoiesis. In vitro and in vivo study models. Ann. N. Y. Acad. Sci. 917, 724-731.
42. SATO, T., NUNOMURA, S., SATO, C., HOZUMI, K., KUMAGAI, Y., NISHIMURA, T., et al. (1999). CD45 can act as a negative regulator for the transition from early to late CD+ CD8+ thymocytes. Int. Immunol. 11, 89-97.
43. SEBZDA, E., WALLACE, V.A., MAYER, J., YEUNG, R.S., MAK, T.W., and OHASHI, P.S. (1994). Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 263, 1615-1618.
44. SILVA-SANTOS, B., PENNINGTON, D.J., and HAYDAY, A.C. (2005). Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors. Science 307, 925-928.
45. STARR, T.K., JAMESON, S.C., and HOGQUIST, K.A. (2003). Positive and negative selection of T cells. Annu. Rev. Immunol. 21, 139-176.
46. TOYOOKA, K., TAI, X.G., PARK, C.S., YASHIRO, Y., HAMAOKA, T., and FUJIWARA. H. (1998). A caspase inhibitor protects thymocytes from diverse signal-mediated apoptosis but not from clonal deletion in fetal thymus organ culture. Immunol. Lett. 63, 83-89.
47. UENO, T., HARA, K., WILLIS, M.S., MALIN, M.A., HOPKEN, U.E., GRAY, D.H., et al. (2002). Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity 16, 205-218.
48. WITT, C.M., and ROBEY, E.A. (2005). Thymopoiesis in 4 dimensions. Semin. Immunol. 17, 95-102.
49. YARILIN, A.A., and BELYAKOV, I.M. (2004). Cytokines in the thymus: Production and biological effects. Curr. Med. Chem. 11, 447-464.
50. YONEHARA, S., NISHIMURA, Y., KISHIL, S., YONEHARA, M., TAKAZAWA, K., TAMATANI, T., et al. (1994). Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes. Int. Immunol. 6, 1849-1854.