Increased levels of pigment epithelium-derived factor in aqueous humor of patients with uveitis

British Journal of Ophthalmology

Volumn 91, Issue 2, 2007, Pages 149-150

  Yoshida, Yumiko ^a   Yamagishi, Sho Ichi ^a   Matsui, Takanori ^a   Nakamura, Kazuo ^a   Imaizumi, Tsutomu ^a   Yoshimura, Koichi ^a   Yamakawa, Ryoji ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; CATARACT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EYE INFLAMMATION; HUMAN; PRIORITY JOURNAL; UVEITIS;

ADULT; AGED; AQUEOUS HUMOR; EYE INFECTIONS; EYE PROTEINS; HUMANS; MIDDLE AGED; NERVE GROWTH FACTORS; SERPINS; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA; UVEITIS;

EID: 33846845062     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.103804     Document Type: Article

References (7)

1. Tombran-Tink J, Chader CG, Johnson LV. PEDF: pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res 1991;53:411-14.
2. Duh EJ, Yang HS, Suzuma I, et al. Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci 2002;43:821-9.
3. Zhang SX, Wang JJ, Gao G, et al. Pigment epithelium-derived factor (PEDF) is an endogenous anti-inflammatory factor. FASEB J 2006;20:323-5.
4. Spranger J, Osterhoff M, Reimann M, et al. Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease. Diabetes 2002;50:2641-5.
5. Yamagishi S, Adachi H, Abe A, et al. Elevated serum levels of pigment epithelium-derived factor (PEDF) in the metabolic syndrome. J Clin Endocrimol Metab 2006;91:2447-50.
6. Verma MJ, Lloyd A, Rager H, et al. Chemokines in acute anterior uveitis. Curr Eye Res 1997;16:1202-8.
7. Yamagishi S, Inagaki Y, Nakamura K, et al. Pigment epithelium-derived factor inhibits TNF-alpha-induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase-mediated reactive oxygen species generation. J Mol Cell Cardiol 2004;37:497-506.