-
1
-
-
0035941230
-
The transmembrane heregulin precursor is functionally active
-
Aguilar, Z., and Slamon, D. J. (2001). The transmembrane heregulin precursor is functionally active. J. Biol. Chem. 276, 44099-44107.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 44099-44107
-
-
Aguilar, Z.1
Slamon, D.J.2
-
2
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
Agus, D., et al. (2002). Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2, 127-137.
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.1
-
3
-
-
0025372020
-
Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor a to epidermal growth factor receptors promotes cell proliferation
-
Anklesaria, P., Teixidó, J., Laiho, M., Pierce, J. H., Greenberger, J. S., and Massagué, J. (1990). Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor a to epidermal growth factor receptors promotes cell proliferation. Proc. Natl. Acad. Sci. USA 87, 3289-3293.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3289-3293
-
-
Anklesaria, P.1
Teixidó, J.2
Laiho, M.3
Pierce, J.H.4
Greenberger, J.S.5
Massagué, J.6
-
4
-
-
0030038201
-
Autocrine regulation of membrane transforming growth factor-a cleavage
-
Baselga, J., Mendelsohn, J., Kim, Y. M., and Pandiella, A. (1996). Autocrine regulation of membrane transforming growth factor-a cleavage. J. Biol. Chem. 271, 3279-3284.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 3279-3284
-
-
Baselga, J.1
Mendelsohn, J.2
Kim, Y.M.3
Pandiella, A.4
-
5
-
-
11244261160
-
ADAMs: Key components in EGFR signalling and development
-
Blobel, C. P. (2005). ADAMs: key components in EGFR signalling and development. Nat. Rev. Mol. Cell Biol. 6, 32-43.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 32-43
-
-
Blobel, C.P.1
-
6
-
-
0037416187
-
TACE is required for the activation of the EGFR by TGF-alpha in tumors
-
Borrell-Pages, M., Rojo, F., Albanell, J., Baselga, J., and Arribas, J. (2003). TACE is required for the activation of the EGFR by TGF-alpha in tumors. EMBO J. 22, 1114-1124.
-
(2003)
EMBO J
, vol.22
, pp. 1114-1124
-
-
Borrell-Pages, M.1
Rojo, F.2
Albanell, J.3
Baselga, J.4
Arribas, J.5
-
7
-
-
0027071814
-
The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF-α into soluble growth factor
-
Bosenberg, M. W., Pandiella, A., and Massagué, J. (1992). The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF-α into soluble growth factor. Cell 71, 1157-1165.
-
(1992)
Cell
, vol.71
, pp. 1157-1165
-
-
Bosenberg, M.W.1
Pandiella, A.2
Massagué, J.3
-
8
-
-
0024552613
-
Transmembrane TGF-α precursors activate EGF/TGF-α receptors
-
Brachmann, R., Lindquist, P. B., Nagashima, M., Kohr, W., Lipari, T., Napier, N., and Derynck, R. (1989). Transmembrane TGF-α precursors activate EGF/TGF-α receptors. Cell 56, 691-700.
-
(1989)
Cell
, vol.56
, pp. 691-700
-
-
Brachmann, R.1
Lindquist, P.B.2
Nagashima, M.3
Kohr, W.4
Lipari, T.5
Napier, N.6
Derynck, R.7
-
9
-
-
1842332725
-
The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing
-
Briley, G. P., Hissong, M. A., Chiu, M. L., and Lee, D. C. (1997). The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing. Mol. Biol. Cell 8, 1619-1631.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 1619-1631
-
-
Briley, G.P.1
Hissong, M.A.2
Chiu, M.L.3
Lee, D.C.4
-
10
-
-
0032525784
-
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
-
Britsch, S., Li, L., Kirchhoff, S., Theuring, F., Brinkmann, V., Birchmeier, C., and Riethmacher, D. (1998). The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev. 12, 1825-1836.
-
(1998)
Genes Dev
, vol.12
, pp. 1825-1836
-
-
Britsch, S.1
Li, L.2
Kirchhoff, S.3
Theuring, F.4
Brinkmann, V.5
Birchmeier, C.6
Riethmacher, D.7
-
11
-
-
10744230127
-
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
-
Burgess, A. W., Cho, H. S., Eigenbrot, C., Ferguson, K. M., Garrett, T. P., Leahy, D. J., Lemmon, M. A., Sliwkowski, M. X., Ward, C. W., and Yokoyama, S. (2003). An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol. Cell 12, 541-552.
-
(2003)
Mol. Cell
, vol.12
, pp. 541-552
-
-
Burgess, A.W.1
Cho, H.S.2
Eigenbrot, C.3
Ferguson, K.M.4
Garrett, T.P.5
Leahy, D.J.6
Lemmon, M.A.7
Sliwkowski, M.X.8
Ward, C.W.9
Yokoyama, S.10
-
12
-
-
0029153655
-
Biosynthetic processing of neu differentiation factor. Glycosylation trafficking, and regulated cleavage from the cell surface
-
Burgess, T. L., Ross, S. L., Qian, Y. X., Brankow, D., and Hu, S. (1995). Biosynthetic processing of neu differentiation factor. Glycosylation trafficking, and regulated cleavage from the cell surface. J. Biol. Chem. 270, 19188-19196.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 19188-19196
-
-
Burgess, T.L.1
Ross, S.L.2
Qian, Y.X.3
Brankow, D.4
Hu, S.5
-
13
-
-
0031009806
-
Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus
-
Busfield, S. J., et al. (1997). Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus. Mol. Cell. Biol. 17, 4007-4014.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 4007-4014
-
-
Busfield, S.J.1
-
14
-
-
0030020074
-
TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment
-
Cabrera, N., Díaz-Rodríguez, E., Becker, E., Zanca, D. M., and Pandiella, A. (1996). TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment. J. Cell Biol. 132, 427-436.
-
(1996)
J. Cell Biol
, vol.132
, pp. 427-436
-
-
Cabrera, N.1
Díaz-Rodríguez, E.2
Becker, E.3
Zanca, D.M.4
Pandiella, A.5
-
15
-
-
0030974096
-
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
-
Carraway, K. L., 3rd, Weber, J. L., Unger, M. J., Ledesma, J., Yu, N., Gassmann, M., and Lai, C. (1997). Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 387, 512-516.
-
(1997)
Nature
, vol.387
, pp. 512-516
-
-
Carraway 3rd, K.L.1
Weber, J.L.2
Unger, M.J.3
Ledesma, J.4
Yu, N.5
Gassmann, M.6
Lai, C.7
-
16
-
-
0030911331
-
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
-
Chang, H., Riese, D. J., 2nd, Gilbert, W., Stern, D. F., and McMahan, U. J. (1997). Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature 387, 509-512.
-
(1997)
Nature
, vol.387
, pp. 509-512
-
-
Chang, H.1
Riese 2nd, D.J.2
Gilbert, W.3
Stern, D.F.4
McMahan, U.J.5
-
17
-
-
0025779606
-
Membrane-anchored forms of EGF stimulate focus formation and intercellular communication
-
Dobashi, Y., and Stern, D. F. (1991). Membrane-anchored forms of EGF stimulate focus formation and intercellular communication. Oncogene 6, 1151-1159.
-
(1991)
Oncogene
, vol.6
, pp. 1151-1159
-
-
Dobashi, Y.1
Stern, D.F.2
-
18
-
-
19644373566
-
The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode
-
Dong, J., Opresko, L. K., Chrisler, W., Orr, G., Quesenberry, R. D., Lauffenburger, D. A., and Wiley, H. S. (2005). The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode. Mol. Biol. Cell 16, 2984-2998.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2984-2998
-
-
Dong, J.1
Opresko, L.K.2
Chrisler, W.3
Orr, G.4
Quesenberry, R.D.5
Lauffenburger, D.A.6
Wiley, H.S.7
-
19
-
-
0032991651
-
Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor
-
Dong, J., Opresko, L. K., Dempsey, P. J., Lauffenburger, D. A., Coffey, R. J., and Wiley, H. S. (1999). Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor. Proc. Natl. Acad. Sci. USA 96, 6235-6240.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6235-6240
-
-
Dong, J.1
Opresko, L.K.2
Dempsey, P.J.3
Lauffenburger, D.A.4
Coffey, R.J.5
Wiley, H.S.6
-
20
-
-
0037336295
-
Quality control in the endoplasmic reticulum
-
Ellgaard, L., and Helenius, A. (2003). Quality control in the endoplasmic reticulum. Nat. Rev. Mol. Cell Biol. 4, 181-191.
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 181-191
-
-
Ellgaard, L.1
Helenius, A.2
-
21
-
-
0036133133
-
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2
-
Esparis-Ogando, A., Diaz-Rodriguez, E., Montero, J. C., Yuste, L., Crespo, P., and Pandiella, A. (2002). Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2. Mol. Cell. Biol. 22, 270-285.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 270-285
-
-
Esparis-Ogando, A.1
Diaz-Rodriguez, E.2
Montero, J.C.3
Yuste, L.4
Crespo, P.5
Pandiella, A.6
-
22
-
-
1642616755
-
Signalling-competent truncated forms of ErbB2 in breast cancer cells: Differential regulation by protein kinase C and phosphatidylinositol 3-kinase
-
Esparís-Ogando, A., Díaz-Rodríguez, E., and Pandiella, A. (1999). Signalling-competent truncated forms of ErbB2 in breast cancer cells: differential regulation by protein kinase C and phosphatidylinositol 3-kinase. Biochem. J. 344, 339-348.
-
(1999)
Biochem. J
, vol.344
, pp. 339-348
-
-
Esparís-Ogando, A.1
Díaz-Rodríguez, E.2
Pandiella, A.3
-
23
-
-
0037429649
-
Neuregulins: Functions, forms, and signaling strategies
-
Falls, D. L. (2003). Neuregulins: functions, forms, and signaling strategies. Exp. Cell Res. 284, 14-30.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 14-30
-
-
Falls, D.L.1
-
24
-
-
0033120592
-
A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface
-
Fernandez-Larrea, J., Merlos-Suarez, A., Urena, J. M., Baselga, J., and Arribas, J. (1999). A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface. Mol. Cell 3, 423-433.
-
(1999)
Mol. Cell
, vol.3
, pp. 423-433
-
-
Fernandez-Larrea, J.1
Merlos-Suarez, A.2
Urena, J.M.3
Baselga, J.4
Arribas, J.5
-
25
-
-
0031059146
-
ARIA: A neuromuscular junction neuregulin
-
Fischbach, G. D., and Rosen, K. M. (1997). ARIA: a neuromuscular junction neuregulin. Annu. Rev. Neurosci. 20, 429-458.
-
(1997)
Annu. Rev. Neurosci
, vol.20
, pp. 429-458
-
-
Fischbach, G.D.1
Rosen, K.M.2
-
26
-
-
0029855245
-
The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
-
Golembo, M., Raz, E., and Shilo, B. Z. (1996). The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122, 3363-3370.
-
(1996)
Development
, vol.122
, pp. 3363-3370
-
-
Golembo, M.1
Raz, E.2
Shilo, B.Z.3
-
27
-
-
0032055472
-
Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins
-
Gut, A., Kappeler, F., Hyka, N., Balda, M. S., Hauri, H. P., and Matter, K. (1998). Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins. EMBO J. 17, 1919-1929.
-
(1998)
EMBO J
, vol.17
, pp. 1919-1929
-
-
Gut, A.1
Kappeler, F.2
Hyka, N.3
Balda, M.S.4
Hauri, H.P.5
Matter, K.6
-
28
-
-
0033614356
-
Neuregulin-4, a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
-
Harari, D., Tzahar, E., Romano, J., Shelly, M., Pierce, J. H., Andrews, G. C., and Yarden, Y. (1999). Neuregulin-4, a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase. Oncogene 18, 2681-2689.
-
(1999)
Oncogene
, vol.18
, pp. 2681-2689
-
-
Harari, D.1
Tzahar, E.2
Romano, J.3
Shelly, M.4
Pierce, J.H.5
Andrews, G.C.6
Yarden, Y.7
-
29
-
-
0037429706
-
EGF receptor ligands
-
Harris, R. C., Chung, E., and Coffey, R. J. (2003). EGF receptor ligands. Exp. Cell Res. 284, 2-13.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 2-13
-
-
Harris, R.C.1
Chung, E.2
Coffey, R.J.3
-
30
-
-
0036796421
-
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts
-
Hartmann, D., et al. (2002). The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Hum. Mol. Genet. 11, 2615-2624.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 2615-2624
-
-
Hartmann, D.1
-
31
-
-
0028963636
-
The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor
-
Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N., Klagsbrun, M., and Mekada, E. (1995). The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J. Cell Biol. 128, 929-938.
-
(1995)
J. Cell Biol
, vol.128
, pp. 929-938
-
-
Higashiyama, S.1
Iwamoto, R.2
Goishi, K.3
Raab, G.4
Taniguchi, N.5
Klagsbrun, M.6
Mekada, E.7
-
32
-
-
2642541715
-
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: The juxtamembrane stalk determines cleavage efficiency
-
Hinkle, C. L., Sunnarborg, S. W., Loiselle, D., Parker, C. E., Stevenson, M., Russell, W. E., and Lee, D. C. (2004). Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J. Biol. Chem. 279, 24179-24188.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24179-24188
-
-
Hinkle, C.L.1
Sunnarborg, S.W.2
Loiselle, D.3
Parker, C.E.4
Stevenson, M.5
Russell, W.E.6
Lee, D.C.7
-
33
-
-
19444368039
-
Selective Golgi export of Kir2.1 controls the stoichiometry of functional Kir2.x channel heteromers
-
Hofherr, A., Fakler, B., and Klocker, N. (2005). Selective Golgi export of Kir2.1 controls the stoichiometry of functional Kir2.x channel heteromers. J. Cell Sci. 118, 1935-1943.
-
(2005)
J. Cell Sci
, vol.118
, pp. 1935-1943
-
-
Hofherr, A.1
Fakler, B.2
Klocker, N.3
-
34
-
-
0026659262
-
erbB2
-
erbB2. Science 256, 1205-1210.
-
(1992)
Science
, vol.256
, pp. 1205-1210
-
-
Holmes, W.E.1
-
35
-
-
22144479011
-
N-terminal cleavage of proTGFalpha occurs at the cell surface by a TACE-independent activity
-
Juanes, P. P., Ferreira, L., Montero, J. C., Arribas, J., and Pandiella, A. (2005). N-terminal cleavage of proTGFalpha occurs at the cell surface by a TACE-independent activity. Biochem. J. 389, 161-172.
-
(2005)
Biochem. J
, vol.389
, pp. 161-172
-
-
Juanes, P.P.1
Ferreira, L.2
Montero, J.C.3
Arribas, J.4
Pandiella, A.5
-
36
-
-
3142587059
-
Protein folding and quality control in the endoplasmic reticulum
-
Kleizen, B., and Braakman, I. (2004). Protein folding and quality control in the endoplasmic reticulum. Curr. Opin. Cell Biol. 16, 343-349.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 343-349
-
-
Kleizen, B.1
Braakman, I.2
-
37
-
-
0029839393
-
Transmembrane domain of influenza virus neuraminidase, a type II protein, possesses an apical sorting signal in polarized MDCK cells
-
Kundu, A., Avalos, R. T., Sanderson, C. M., and Nayak, D. P. (1996). Transmembrane domain of influenza virus neuraminidase, a type II protein, possesses an apical sorting signal in polarized MDCK cells. J. Virol. 70, 6508-6515.
-
(1996)
J. Virol
, vol.70
, pp. 6508-6515
-
-
Kundu, A.1
Avalos, R.T.2
Sanderson, C.M.3
Nayak, D.P.4
-
38
-
-
0033996361
-
ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: Receptor overexpression does not determine growth dependency
-
Lane, H. A., Beuvink, I., Motoyama, A. B., Daly, J. M., Neve, R. M., and Hynes, N. E. (2000). ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency. Mol. Cell. Biol. 20, 3210-3223.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 3210-3223
-
-
Lane, H.A.1
Beuvink, I.2
Motoyama, A.B.3
Daly, J.M.4
Neve, R.M.5
Hynes, N.E.6
-
39
-
-
0028924274
-
Post-translational processing of membrane-associated neu differentiation factor proisoforms expressed in mammalian cells
-
Lu, H. S., et al. (1995). Post-translational processing of membrane-associated neu differentiation factor proisoforms expressed in mammalian cells. J. Biol. Chem. 270, 4775-4783.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 4775-4783
-
-
Lu, H.S.1
-
40
-
-
0021013896
-
Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells
-
Massague, J. (1983). Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells. J. Biol. Chem. 258, 13614-13620.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 13614-13620
-
-
Massague, J.1
-
41
-
-
0027236997
-
Membrane-anchored growth factors
-
Massagué, J., and Pandiella, A. (1993). Membrane-anchored growth factors. Annu. Rev. Biochem. 62, 515-541.
-
(1993)
Annu. Rev. Biochem
, vol.62
, pp. 515-541
-
-
Massagué, J.1
Pandiella, A.2
-
42
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer, D., and Birchmeier, C. (1995). Multiple essential functions of neuregulin in development. Nature 378, 386-390.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
43
-
-
0030830869
-
Isoform-specific expression and function of neuregulin
-
Meyer, D., Yamaai, T., Garratt, A., Riethmacher-Sonnenberg, E., Kane, D., Theill, L. E., and Birchmeier, C. (1997). Isoform-specific expression and function of neuregulin. Development 124, 3575-3586.
-
(1997)
Development
, vol.124
, pp. 3575-3586
-
-
Meyer, D.1
Yamaai, T.2
Garratt, A.3
Riethmacher-Sonnenberg, E.4
Kane, D.5
Theill, L.E.6
Birchmeier, C.7
-
44
-
-
0034533443
-
Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-α converting enzyme
-
Montero, J. C., Yuste, L., Díaz-Rodríguez, E., Esparís-Ogando, A., and Pandiella, A. (2000). Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-α converting enzyme. Mol. Cell. Neurosci. 16, 631-648.
-
(2000)
Mol. Cell. Neurosci
, vol.16
, pp. 631-648
-
-
Montero, J.C.1
Yuste, L.2
Díaz-Rodríguez, E.3
Esparís-Ogando, A.4
Pandiella, A.5
-
45
-
-
0026776424
-
Isolation of the Neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
-
Peles, E., Bacus, S. S., Koski, R. A., Lu, H. S., Wen, D., Ogden, S. G., Levy, R. B., and Yarden, Y. (1992). Isolation of the Neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells. Cell 69, 205-216.
-
(1992)
Cell
, vol.69
, pp. 205-216
-
-
Peles, E.1
Bacus, S.S.2
Koski, R.A.3
Lu, H.S.4
Wen, D.5
Ogden, S.G.6
Levy, R.B.7
Yarden, Y.8
-
46
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J., et al. (1998). An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284.
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
-
47
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., and Ullrich, A. (1999). EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402, 884-888.
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
Leserer, M.4
Abraham, R.5
Wallasch, C.6
Ullrich, A.7
-
48
-
-
1442358746
-
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
-
Sahin, U., Weskamp, G., Kelly, K., Zhou, H. M., Higashiyama, S., Peschon, J., Hartmann, D., Saftig, P., and Blobel, C. P. (2004). Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J. Cell Biol. 164, 769-779.
-
(2004)
J. Cell Biol
, vol.164
, pp. 769-779
-
-
Sahin, U.1
Weskamp, G.2
Kelly, K.3
Zhou, H.M.4
Higashiyama, S.5
Peschon, J.6
Hartmann, D.7
Saftig, P.8
Blobel, C.P.9
-
49
-
-
2342446235
-
Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells
-
Singh, A. B., Tsukada, T., Zent, R., and Harris, R. C. (2004). Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells. J. Cell Sci. 117, 1365-1379.
-
(2004)
J. Cell Sci
, vol.117
, pp. 1365-1379
-
-
Singh, A.B.1
Tsukada, T.2
Zent, R.3
Harris, R.C.4
-
50
-
-
0037593865
-
Surface expression of inward rectifier potassium channels is controlled by selective Golgi export
-
Stockklausner, C., and Klocker, N. (2003). Surface expression of inward rectifier potassium channels is controlled by selective Golgi export. J. Biol. Chem. 278, 17000-17005.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 17000-17005
-
-
Stockklausner, C.1
Klocker, N.2
-
51
-
-
0037066757
-
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
-
Sunnarborg, S. W., et al. (2002). Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J. Biol. Chem. 277, 12838-12845.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 12838-12845
-
-
Sunnarborg, S.W.1
-
52
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich, A., and Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
53
-
-
0029029563
-
trans-Golgi retention of a plasma membrane protein: Mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit H1 result in transGolgi retention
-
Wahlberg, J. M., Geffen, I., Reymond, F., Simmen, T., and Spiess, M. (1995). trans-Golgi retention of a plasma membrane protein: mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit H1 result in transGolgi retention. J. Cell Biol. 130, 285-297.
-
(1995)
J. Cell Biol
, vol.130
, pp. 285-297
-
-
Wahlberg, J.M.1
Geffen, I.2
Reymond, F.3
Simmen, T.4
Spiess, M.5
-
54
-
-
0028269314
-
Structural and functional aspects of the multiplicity of Neu differentiation factors
-
Wen, D., et al. (1994). Structural and functional aspects of the multiplicity of Neu differentiation factors. Mol. Cell. Biol. 14, 1909-1919.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 1909-1919
-
-
Wen, D.1
-
55
-
-
0032583167
-
Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization
-
Wiley, H. S., Woolf, M. F., Opresko, L. K., Burke, P. M., Will, B., Morgan, J. R., and Lauffenburger, D. A. (1998). Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization. J. Cell Biol. 143, 1317-1328.
-
(1998)
J. Cell Biol
, vol.143
, pp. 1317-1328
-
-
Wiley, H.S.1
Woolf, M.F.2
Opresko, L.K.3
Burke, P.M.4
Will, B.5
Morgan, J.R.6
Lauffenburger, D.A.7
-
56
-
-
0024504360
-
The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
-
Wong, S. T., Winchell, L. F., McCune, B. K., Earp, H. S., Teixidó, J., Massagué, J., Herman, B., and Lee, D. C. (1989). The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 56, 495-506.
-
(1989)
Cell
, vol.56
, pp. 495-506
-
-
Wong, S.T.1
Winchell, L.F.2
McCune, B.K.3
Earp, H.S.4
Teixidó, J.5
Massagué, J.6
Herman, B.7
Lee, D.C.8
-
57
-
-
10744230888
-
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
-
Yamazaki, S., et al. (2003). Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities. J. Cell Biol. 163, 469-475.
-
(2003)
J. Cell Biol
, vol.163
, pp. 469-475
-
-
Yamazaki, S.1
-
58
-
-
0034611607
-
Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells
-
Yang, H., Jiang, D., Li, W., Liang, J., Gentry, L. E., and Brattain, M. G. (2000). Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells. Oncogene 19, 1901-1914.
-
(2000)
Oncogene
, vol.19
, pp. 1901-1914
-
-
Yang, H.1
Jiang, D.2
Li, W.3
Liang, J.4
Gentry, L.E.5
Brattain, M.G.6
-
59
-
-
0030726211
-
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells
-
Yeaman, C., Le Gall, A. H., Baldwin, A. N., Monlauzeur, L., Le Bivic, A., and Rodriguez-Boulan, E. (1997). The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. J. Cell Biol. 139, 929-940.
-
(1997)
J. Cell Biol
, vol.139
, pp. 929-940
-
-
Yeaman, C.1
Le Gall, A.H.2
Baldwin, A.N.3
Monlauzeur, L.4
Le Bivic, A.5
Rodriguez-Boulan, E.6
-
60
-
-
23044436390
-
Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin
-
Yuste, L., Montero, J. C., Esparis-Ogando, A., and Pandiella, A. (2005). Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin. Cancer Res. 65, 6801-6810.
-
(2005)
Cancer Res
, vol.65
, pp. 6801-6810
-
-
Yuste, L.1
Montero, J.C.2
Esparis-Ogando, A.3
Pandiella, A.4
-
61
-
-
12644279865
-
Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
-
Zhang, D., Sliwkowski, M. X., Mark, M., Frantz, G., Akita, R., Sun, Y., Hillan, K., Crowley, C., Brush, J., and Godowski, P. J. (1997). Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc. Natl. Acad. Sci. USA 94, 9562-9567.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9562-9567
-
-
Zhang, D.1
Sliwkowski, M.X.2
Mark, M.3
Frantz, G.4
Akita, R.5
Sun, Y.6
Hillan, K.7
Crowley, C.8
Brush, J.9
Godowski, P.J.10
|