Oxycodone accumulation in a hemodialysis patient

Southern Medical Journal

Volumn 100, Issue 2, 2007, Pages 212-214

  Foral, Pamela A ^a   Ineck, Joseph R ^a   Nystrom, Kelly K ^a  

^a CREIGHTON UNIVERSITY   (United States)

Author keywords

Hemodialysis; Opioids; Oxycodone; Renal failure; Toxicity

Indexed keywords

HYDROMORPHONE; NALOXONE; OXYCODONE; PARACETAMOL; PHENYLEPHRINE;

ADULT; ANALGESIA; ANAMNESIS; APNEA; ARTICLE; CASE REPORT; CONTINUOUS INFUSION; DRUG DOSE TITRATION; DRUG WITHDRAWAL; GRAFT INFECTION; HEMODIALYSIS; HUMAN; HYPOTENSION; KIDNEY FAILURE; LETHARGY; MALE; MULTIPLE CYCLE TREATMENT; OSTEOMYELITIS; PAIN; RESPIRATION DEPRESSION;

ADULT; ANALGESICS, OPIOID; FOLLOW-UP STUDIES; HUMANS; HYPOTENSION; KIDNEY FAILURE, CHRONIC; LETHARGY; MALE; OXYCODONE; RENAL DIALYSIS; RESPIRATORY INSUFFICIENCY;

EID: 33846829692     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.smj.0000242876.45747.0a     Document Type: Article

References (14)

1. Schiff PL. Opium and its alkaloids. Am J Pharm Educ 2002;66:186-194.
2. American Pain Society. Principles of Analgesic Use in the Treatment of Acute Pain and Cancer Pain. 5th ed. Glenview, IL, 2003.
3. Kaiko R, Lacouture P, Hopf K, et al. Analgesic onset and potency of oral controlled-released (CR) oxycodone and CR morphine (abstract). Clin Pharmacol Ther 1996;59:130.
4. Robson P. The use of opioids in palliative care patients with renal failure. Cancer Medicine 2004;2:40-48.
5. Heiskanen T, Olkkola KT, Kalso E. Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. Clin Pharmacol Ther 1998;64:603-611.
6. Baselt RC, Stewart CB. Determination of oxycodone and major metabolite in urine by electron-capture GLC. J Anal Toxicol 1978;2:107-109.
7. Pöyhiä R, Seppälä T, Olkkola KT, et al. The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects. Br J Pharmacol 1992;33:617-621.
8. Kirvela M, Lindgren L, Seppala T, et al. The pharmacokinetics of oxycodone in uremia patients undergoing renal transplantation. J Clin Anesth 1996;8:13-18.
9. Benziger DP, Cheng C, Miotto J, et al. Comparative pharmacokinetics of controlled release oxycodone (OxyContin) in special populations. In: Abstracts, 8th World Congress on Pain. IASP Press, Seattle, WA, 1996:285.
10. Kaiko R, Benziger D, Cheng C, et al. Clinical pharmacokinetics of controlled release oxycodone in renal impairment (abstract). Clin Pharmacol Ther 1996;59:130.
11. Fitzgerald J. Narcotic analgesics in renal failure. Conn Med 1991;55:701-704.
12. Dean M. Opioids in renal failure and dialysis patients. J Pain Symptom Manage 2004;28:497-504.
13. Lee MA, Leng ME, Cooper RM. Measurements of plasma oxycodone, noroxycodone andoxymorphone levels in a patient with bilateral nephrectomy who is undergoing haemodialysis. Palliat Med 2005;19:259-260.
14. Naranjo CA, Busto U, Sellers EM, et al. A method of estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245.