Focus on Molecules: Glial fibrillary acidic protein (GFAP)

Experimental Eye Research

Volumn 84, Issue 3, 2007, Pages 381-382

  Sarthy, Vijay ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Alexander disease; astrocyte; gliosis; intermediate filaments; M ller cell; retina

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN;

ALEXANDER DISEASE; ASTROCYTE; DRUSEN; GLAUCOMA; GLIA CELL; KNOCKOUT MOUSE; MISSENSE MUTATION; MOLECULAR GENETICS; MUELLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RETINA DEGENERATION; RETINA DETACHMENT; RETINA INJURY; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; SHORT SURVEY;

ALEXANDER DISEASE; ASTROCYTES; BASE SEQUENCE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INTERMEDIATE FILAMENTS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; RETINA;

EID: 33846820516     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.12.014     Document Type: Short Survey

References (4)

1. Eng L.F., Ghirnikar R.S., and Lee Y.L. Glial fibrillary acidic protein: GFAP-thirty-one-years (1969-2000). Neurochem. Res. 25 (2000) 1439-1451
2. Sarthy V., and Ripps H. The Retinal Müller Cell-Structure and Function (2001), Kluwer Academic/Plenum Press, New York, NY
3. Lundkvist A., Reichenbach A., Betsholtz C., Carmeliet P., Wolburg H., and Pekny M. Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences. J. Cell Sci. 117 (2004) 3481-3488
4. Brenner M., Johnson A.B., Boespflug-Tanguy O., Rodriguez D., Goldman J.E., and Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat. Genet. 27 (2001) 117-120