Specific antibody index in cerebrospinal fluid from patients with central and peripheral paraneoplastic neurological syndromes

Journal of Neuroimmunology

Volumn 183, Issue 1-2, 2007, Pages 220-224

  Stich, Oliver ^a   Jarius, Sven ^b,c   Kleer, Barbara ^a   Rasiah, Christiane ^d   Voltz, Raymond ^e   Rauer, Sebastian ^a,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^d RAVO DIAGNOSTIKA GMBH   (Germany)

^e UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Clinical immunologic correlation; Intrathecal antibody synthesis; Paraneoplastic neurological syndromes; Recombinant ELISA; Specific antibody index

Indexed keywords

AMPHIPHYSIN; RECOMBINANT ANTIGEN;

ADULT; AGED; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; BLOOD LEVEL; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; NEUROLOGIC DISEASE; PARANEOPLASTIC NEUROPATHY; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADULT; AGED; ANTIBODIES; ANTIBODY SPECIFICITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PARANEOPLASTIC SYNDROMES, NERVOUS SYSTEM;

EID: 33846820308     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.11.008     Document Type: Article

References (21)

1. Arvidson B. Distribution of intravenously injected protein tracers in peripheral ganglia of adult mice. Exp. Neurol. 63 2 (1979) 388-410
2. Dalmau J., Graus F., Rosenblum M.K., and Posner J.B. Anti-Hu-associated paraneoplastic encephalomyelitis/Sensory neuronopathy. Medicine 71 (1992) 59-72
3. Darnell R.B. Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity and the brain. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 4529-4536
4. Felgenhauer K., and Reiber H. The diagnostic significance of antibody specificity indices in multiple sclerosis and herpes virus induced diseases of the nervous system. Clin. Investig. 70 1 (1992) 28-37 (Jan)
5. Furneaux H.F., Reich L., and Posner J.B. Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes. Neurology 40 7 (1990) 1085-1091
6. Graus F., Delattre J.Y., Antoine J.C., Dalmau J., Giometto B., Grisold W., Honnorat J., Smitt P.S., Verdeler Ch., Verschuuren J.J., Vincent A., and Voltz R. Recommended diagnostic criteria for paraneoplastic neurological syndromes. J. Neurol. Neurosurg. Psychiatry 75 8 (2004) 1135-1140 (Aug)
7. Luer W., Poser S., Weber T., Jurgens S., Eichenlaub D., Pohle H.D., and Felgenhauer K. Chronic HIV encephalitis-I. Cerebrospinal fluid diagnosis. Klin. Wochenschr. 66 1 (1988) 21-25 (Jan 4)
8. Pellkofer H., Schubart A.S., Hoftberger R., Schutze N., Pagany M., Schuller M., Lassmann H., Hohlfeld R., Voltz R., and Linington C. Modelling paraneoplastic CNS disease: T-cells specific for the onconeuronal antigen PNMA1 mediate autoimmune encephalomyelitis in the rat. Brain 127 Pt 8 (2004) 1822-1830 (Aug)
9. Posner J.B. Neurologic Complications of Cancer (1995), FA Davis Company, Philadelphia 353-385
10. Pozo-Rosich P., Clover L., Saiz A., Vincent A., and Graus F. Voltage-gated potassium channel antibodies in limbic encephalitis. Ann. Neurol. 54 4 (2003) 530-533 (Oct)
11. Rauer S., and Kaiser R. Demonstration of anti-HuD specific oligoclonal bands in the cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Qualitative evidence of anti-HuD specific IgG-synthesis in the central nervous system. J. Neuroimmunol. 111 1-2 (2000) 241-244
12. Rauer S., and Kaiser R. Enzyme linked immunosorbent assay using recombinant HuD-autoantigen for serodiagnosis of paraneoplastic neurological syndromes. Acta Neurol. Scand. 103 4 (2001) 248-254
13. Reiber H., and Peter J.B. Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs. J. Neurol. Sci. 184 (2000) 101-122
14. Roberts W.K., and Darnell R.B. Neuroimmunology of the paraneoplastic neurological degenerations. Curr. Opin. Immunol. 16 5 (2004) 616-622
15. Stich O., and Rauer S. Qualitative evidence of anti-Ri specific intrathecal antibody synthesis and quantification of anti-Ri antibodies in serial samples from a patient with anti-Ri syndrome. J. Neurol. Neurosurg. Psychiatry 77 2 (2006) 282-283
16. Stich O., Graus F., Rasiah C., and Rauer S. Qualitative evidence of anti-Yo-specific intrathecal antibody synthesis in patients with paraneoplastic cerebellar degeneration. J. Neuroimmunol. 141 1-2 (2003) 165-169
17. Tanaka K., Tanaka M., Igarashi S., Onodera O., Miyatake T., and Tsuji S. Trial to establish an animal model of paraneoplastic cerebellar degeneation with anti-Yo antibody. 2. Passive transfer of murine mononuclear cells activated with recombinant Yo protein to paraneoplastic cerebellar degeneration lymphocytes in severe combined immunodeficiency mice. Clin. Neurol. Neurosurg. 97 1 (1995) 101-105
18. Tanaka M., Tanaka K., Onodera O., and Tsuji S. Trial to establish an animal model of paraneoplastic cerebellar degeneration with anti-Yo antibody. 1. Mouse strains bearing different MHC molecules produce antibodies on immunization with recombinant Yo protein, but do not cause Purkinje cell loss. Clin. Neurol. Neurosurg. 97 1 (1995) 95-100
19. Tumani H., Nolker G., and Reiber H. Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis. Neurology 45 9 (1995) 1663-1670 (Sep)
20. Vega F., Graus F., Chen Q.M., Poisson M., Schuller E., and Delattre J.Y. Intrathecal synthesis of the anti-Hu antibody in patients with paraneoplastic encephalomyelitis or sensory neuronopathy: clinical-immunologic correlation. Neurology 44 11 (1994) 2145-2147
21. Voltz R.D. Paraneoplastic neurological syndromes: an update on diagnosis, pathogenesis, and therapy. Lancet Neurol. 1 (2002) 294-305