Comparison between topical use of ketotifen and olopatadine in the treatment of allergic conjunctivitis;Compara̧ão do uso tópico de cetotifeno com a olopatadina no tratamento de conjuntivites alérgicas

Arquivos Brasileiros de Oftalmologia

Volumn 64, Issue 5, 2001, Pages 415-422

  Höfling Lima, Ana Luisa ^a   Andrade, Alfredo J M ^a   Marback, Patrícia M F ^a   Farah, Michel Eid ^a   Mascaro, Vera ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Conjunctivitis, allergic drug therapy; Dibenzoxepins therapeutic use; Ketotifen therapeutic use; Ophthalmic solutions

Indexed keywords

EID: 33846816420     PISSN: 00042749     EISSN: 16782925     Source Type: Journal    
DOI: 10.1590/S0004-27492001000500009     Document Type: Article

References (20)

1. Sheldrick JH, Vernon SA, Wilson A, Read SJ. Demand incidence and episode rates of ophthalmic disease in a defined urban population. BMJ 1992; 305:933-6.
2. Brody JM, Foster CS. Vernal conjunctivitis. In: Pepose JS, Holland GN, Wilhelmus KR, editors. Ocular infection & immunity. St Louis: Mosby; 1996. p. 367-75.
3. Liesegang TJ. Atopic keratoconjunctivitis. In: Pepose JS, Holland GN, Wilhelmus KR, editors. Ocular infection & immunity. St Louis: Mosby; 1996. p. 376-90.
4. Reiss J, Abelson MB, George MA, Wedner HJ. Allergic conjunctivitis. In: Pepose JS, Holland GN, Wilhelmus KR, editors. Ocular infection & immunity. St Louis: Mosby; 1996. p. 345-58.
5. McGill JI, Holgate ST, Church MK, Anderson DF, Bacon A. Allergic eye disease mechanisms. Br J Ophthalmol 1998;82:1203-14.
6. Abelson MB, Madiwale N, Weston JH. Conjunctival eosinophils in allergic ocular disease. Arch Ophthalmol 1983;101:555-6.
7. Friedlaender MH, Okumoto Y, Kelley J. Diagnosis of allergic conjunctivitis. Arch Ophthalmol 1984;102:1198-9.
8. Sharif NA, Xu SX, Miller ST, Yanni JM. Olopatadine (AL-4943A): ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis. J Ocul Pharmacol Ther 1996;12:401-7.
9. Carrasco E, Galleguillos F, Bernath Z. The orally administered anti-allergic agent, ketotifen; efficacy in atopic and non-atopic bronchial asthma. Allergol Immunopathol (Madr)1981;9:335-42.
10. Craps L. Ketotifen in the oral prophylaxis of bronchial asthma: a review. Pharmatherapeutica 1981;3:18-35.
11. Heyman SN, Karmeli F, Brezis M, Rachimilewitz D. The effect of ketotifen on nitric oxide synthase activity. Br J Pharmacol 1997;120:1545-51.
12. Grant SM, Goa KL, Fitton A, Sorkin EM. Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. Drugs 1990;40:412-48.
13. Holander M, Wolfe DA. Non-parametric statistical methods. New York: John Wiley & Sons; 1974.
14. Siegel S. Non-parametric statistics for the behavioral sciences. New York: Mc Graw-Hill; 1956.
15. Abelson MB, Spitalny L. Combined analysis of two studies using the conjunctival allergen challenge model to evaluate olopatadine hydrochloride, a new ophthalmic antiallergic agent with dual activity. Am J Ophthalmol 1998; 125:797-804.
16. Mikuni I, Nagajima A, Kogure F, Uchida Y, Kitano S, Shimizu Y, Yuasa T, Mimura Y. Evaluation of ketotifen ophthalmic solution on efficacy and safety on allergy conjunctivitis and vernal conjunctivitis: results on multiclinic open trial. Rinsho Iyaku 1988;4:2371-83.
17. Mikuni I, Nagajima A, Kogure F, Uchida Y, Kitano S, Shimizu Y, Yuasa T, Mimura Y. Clinical effect of ketotifen ophthalmic solution on allergic conjunctivitis and vernal conjunctivitis: multicentre double-blind study in comparisons with disodium cromoglycate ophthalmic solution. Rinsho Hyoka 1989;17:275-9.
18. Abelson MB, Chambers WA, Smith LM. Conjunctival allergen challenge. Arch Ophthalmol 1990;108:84-8.
19. Verin P. Treating severe eye allergy. Clin Exp Allergy 1998;28 Suppl 6:44-8.
20. Bar-Ilan A, Nuemann R. Basic considerations of ocular drug-delivery systems. In: Zimmerman TJ, Kooner KS, Sharir M, Fechtner RD, editors. Textbook of ocular pharmacology. Philadelphia: Lippincott-Raven; 1997. p. 139-55.