The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei

Journal of Molecular Biology

Volumn 366, Issue 4, 2007, Pages 1185-1198

  Martinez Oyanedel, José ^a,b   McNae, Iain W ^a   Nowicki, Matthew W ^a   Keillor, Jeffrey W ^c   Michels, Paul A M ^d   Fothergill Gilmore, Linda A ^a   Walkinshaw, Malcolm D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CONCEPCIÓN   (Chile)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d DE DUVE INSTITUTE   (Belgium)

Author keywords

eukaryote; phosphofructokinase; structure based drug discovery; Trypanosoma brucei; X ray crystallography

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ADENOSINE TRIPHOSPHATE; BACTERIAL ENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBUNIT; EUKARYOTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SPECIES COMPARISON; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

BACTERIA (MICROORGANISMS); BORRELIA BURGDORFERI; EUKARYOTA; MAMMALIA; PROTOZOA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 33846806104     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.10.019     Document Type: Article

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