A mechanism for mutational inactivation of the homeodomain protein TGIF in holoprosencephaly

FASEB Journal

Volumn 21, Issue 2, 2007, Pages 488-496

  Ferrand, Nathalie ^a   Demange, Christine ^a   Prunier, Céline ^b   Su, Ryeon Seo ^a   Atfi, Azeddine ^a  

^a HÔPITAL SAINT ANTOINE   (France)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Nuclear aggregates; Severe forebrain and craniofacial malformations; Transcriptional repression; Ubiquitin dependent degradation

Indexed keywords

HOMEODOMAIN PROTEIN; HOMEODOMAIN PROTEIN TGIF; PROTEASOME; PROTEIN C JUN; SMAD2 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CELL STRAIN HEPG2; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; GENE MUTATION; HOLOPROSENCEPHALY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ALLELES; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; DIMERIZATION; FLUORESCENT ANTIBODY TECHNIQUE; HOLOPROSENCEPHALY; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MODELS, BIOLOGICAL; MUTANT PROTEINS; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC; UBIQUITIN;

EID: 33846786556     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6423com     Document Type: Article

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