Cytokine responses in acute and persistent human parvovirus B19 infection

Clinical and Experimental Immunology

Volumn 147, Issue 3, 2007, Pages 419-425

  Isa, A ^a   Lundqvist, A ^a,b   Lindblom, A ^a   Tolfvenstam, T ^a   Broliden, K ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Sö dra Alvsborgs sjukhus   (Sweden)

Author keywords

Acute infection; Cytokine; Human parvovirus B19; Persistent infection

Indexed keywords

CYTOKINE; DNA; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 2;

ADULT; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROL GROUP; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOKINE RELEASE; ERYTHEMA INFECTIOSUM; FEMALE; FOLLOW UP; HUMAN; IMMUNE DEFICIENCY; IMMUNOASSAY; INFLAMMATION; MALE; PERSISTENT INFECTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEROLOGY; SERUM; SYMPTOMATOLOGY; TH1 CELL; TH2 CELL; VIREMIA; VIRUS IMMUNITY; VIRUS LOAD;

ACUTE DISEASE; ADULT; CHRONIC DISEASE; CROSS-SECTIONAL STUDIES; CYTOKINES; DNA, VIRAL; FEMALE; HISTOCOMPATIBILITY TESTING; HUMANS; INFLAMMATION MEDIATORS; INTERFERON TYPE II; MIDDLE AGED; PARVOVIRIDAE INFECTIONS; PARVOVIRUS B19, HUMAN; TH1 CELLS; TH2 CELLS; VIRAL LOAD;

EID: 33846782953     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2006.03286.x     Document Type: Article

References (24)

1. Young NS, Brown KE. Parvovirus B19. N Engl J Med 2004; 350:586-97.
2. Lindblom A, Isa A, Norbeck O et al. Slow clearance of human parvovirus B19 viremia following acute infection. Clin Infect Dis 2005; 41:1201-3.
3. Norbeck O, Isa A, Pohlmann C et al. Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans. J Virol 2005; 79:12117-21.
4. Isa A, Kasprowicz V, Norbeck O et al. Prolonged Activation of Virus-Specific CD8(+)T Cells after Acute B19 Infection. PLoS Med 2005; 2:e343.
5. Franssila R, Hokynar K, Hedman K. T helper cell-mediated in vitro responses of recently and remotely infected subjects to a candidate recombinant vaccine for human parvovirus b19. J Infect Dis 2001; 183:805-9.
6. Franssila R, Hedman K. T-helper cell-mediated interferon-gamma, interleukin-10 and proliferation responses to a candidate recombinant vaccine for human parvovirus B19. Vaccine 2004; 22:3809-15.
7. Spanakis NE, Garinis GA, Alexopoulos EC et al. Cytokine serum levels in patients with chronic HCV infection. J Clin Lab Anal 2002; 16:40-6.
8. Kerr JR, Cunniffe VS, Kelleher P, Coats AJ, Mattey DL. Circulating cytokines and chemokines in acute symptomatic parvovirus B19 infection: negative association between levels of pro-inflammatory cytokines and development of B19-associated arthritis. JMed Virol 2004; 74:147-55.
9. Kerr JR, Tyrrell DA. Cytokines in parvovirus B19 infection as an aid to understanding chronic fatigue syndrome. Curr Pain Headache Rep 2003; 7:333-41.
10. Lundqvist A, Isa A, Tolfvenstam T, Kvist G, Broliden K. High frequency of parvovirus B19 DNA in bone marrow samples from rheumatic patients. J Clin Virol 2005; 33:71-4.
11. Isa A, Norbeck O, Hirbod T et al. Aberrant cellular immune responses in humans infected persistently with parvovirus B19. J Med Virol 2006; 78:129-33.
12. Olerup O, Zetterquist H. et al. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992; 39:225-35.
13. Comans-Bitter WM, de Groot R, van den Beemd R et al. Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations. J Pediatr 1997; 130:388-93.
14. Yajima T, Yoshihara K, Nakazato K et al. IL-15 Regulates CD8+ T Cell Contraction during Primary Infection. J Immunol 2006; 176:507-15.
15. Becker TC, Wherry EJ, Boone D et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002; 195:1541-8.
16. Bluth MH, Norowitz KB, Chice S et al. Detection of IgE anti-parvovirus B19 and increased CD23+ B cells in parvovirus B19 infection: relation to Th2 cytokines. Clin Immunol 2003; 108:152-8.
17. De Rosa SC, Lu FX, Yu J et al. Vaccination in humans generates broad T cell cytokine responses. J Immunol 2004; 173:5372-80.
18. Becker Y. The changes in the T helper 1 (Th1) and T helper 2 (Th2) cytokine balance during HIV-1 infection are indicative of an allergic response to viral proteins that may be reversed by Th2 cytokine inhibitors and immune response modifiers - a review and hypothesis. Virus Genes 2004; 28:5-18.
19. Rico MA, Quiroga JA, Subira D et al. Hepatitis B virus-specific T-cell proliferation and cytokine secretion in chronic hepatitis B e antibody-positive patients treated with ribavirin and interferon alpha. Hepatology 2001; 33:295-300.
20. Heegaard ED, Petersen BL, Heilmann CJ, Hornsleth A. Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals. J Clin Microbiol 2002; 40:933-6.
21. Lundqvist A, Tolfvenstam T, Brytting M, Stolt CM, Hedman K, Broliden K. Prevalence of parvovirus B19 DNA in bone marrow of patients with haematological disorders. Scand J Infect Dis 1999; 31:119-22.
22. Lundqvist A, Tolfvenstam T, Bostic J, Soderlund M, Broliden K. Clinical and laboratory findings in immunocompetent patients with persistent parvovirus B19 DNA in bone marrow. Scand J Infect Dis 1999; 31:11-6.
23. Hou S, Hyland L, Ryan KW, Portner A, Doherty PC. Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature 1994; 369:652-4.
24. Badovinac VP, Porter BB, Harty JT. Programmed contraction of CD8(+) T cells after infection. Nat Immunol 2002; 3:619-26.