Assessment of digital vascular structure and function in response to bosentan in patients with systemic sclerosis-related Raynaud's phenomenon [1]

Rheumatology

Volumn 46, Issue 2, 2007, Pages 363-364

  Moore, T L ^a   Vail, A ^a   Herrick, Arianne L ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN;

ADULT; AGED; ANALYSIS OF VARIANCE; CLINICAL ARTICLE; CLINICAL PROTOCOL; DISEASE DURATION; FEMALE; FINGER; HUMAN; INFORMED CONSENT; LETTER; LIVER FUNCTION TEST; MALE; OPEN STUDY; PRIORITY JOURNAL; RAYNAUD PHENOMENON; SIDE EFFECT; SYSTEMIC SCLEROSIS; TREATMENT OUTCOME; VASCULARIZATION;

ADULT; AGED; FEMALE; FINGERS; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; RAYNAUD DISEASE; RECEPTORS, ENDOTHELIN; SCLERODERMA, SYSTEMIC; SULFONAMIDES;

EID: 33846709275     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kel383     Document Type: Letter

References (8)

1. Mayes MD. Endothelin and endothelin receptor antagonists in systemic rheumatic disease. Arthritis Rheum 2003;48:1190-9.
2. Korn JH, Mayes M, Matucci Cerinic M et al. Digital ulcers in systemic sclerosis: Prevention by treatment with bosentan, an oral endothelin receptor antagonist. Arthritis Rheum 2004;50:3985-93.
3. Kirchengast M, Munter K. Endothelin-1 and endothelin receptor antagonists in cardiovascular remodeling. PSEBM 1999;221:312-25.
4. Campbell PM, LeRoy EC. Pathogenesis of systemic sclerosis: A vascular hypothesis. Sem Arthritis Rheum 1975;4:351-68.
5. Rodnan GP, Myerowitz RL, Justh GO. Morphological changes in the digital arteries of patients with progressive systemic sclerosis (scleroderma) and Raynauds phenomenon. Medicine 1980;59:393-408.
6. Clark S, Campbell F, Moore T, Jayson MI, King TA, Herrick AL. Laser Doppler imaging - a new technique for quantifying microcirculatory flow in patients with primary Raynaud's phenomenon and systemic sclerosis. Microvascular Research 1999;57:284-91.
7. Anderson ME, Moore TL, Lunt M, Herrick AL. Digital iontophoresis of vasoactive substances as measured by laser Doppler imaginga - A non-invasive technique by which to measure microvascular dysfunction in Raynaud's phenomenon. Rheumatology 2004;43:986-91.
8. Anderson ME, Allen PD, Moore T, Hillier V, Taylor CJ, Herrick AL. Computerised nailfold video capillaroscopy - A new tool for the assessment of Raynaud's phenomenon. J Rheumatol 2005;32:841-8.