Developing a mathematical model for the fission yeast cell cycle: Simulating mutants overexpressing either cdc25 or wee1

Periodica Polytechnica Chemical Engineering

Volumn 50, Issue 2, 2006, Pages 81-94

  Le Thi, Quynh Chi ^a   Sveiczer, Ákos ^a   Novák, Béla ^a  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

Cell cycle; Computer simulation; Fission yeast; Gene overexpressing mutants; Mathematical model

Indexed keywords

CELLS; COMPUTER SIMULATION; MATHEMATICAL MODELS; YEAST;

CELL CYCLE; FISSION YEAST CELL CYCLE; GENE OVEREXPRESSING MUTANTS;

GENETIC ENGINEERING;

CELLS; COMPUTER SIMULATION; GENETIC ENGINEERING; MATHEMATICAL MODELS; YEAST;

EID: 33846706230     PISSN: 03245853     EISSN: 15873765     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Creanor, J.-Mitchison, J. M., The Kinetics of H1 Histone Kinase Activation during the Cell Cycle of Wild-type and wee Mutants of the Fission Yeast Schizosaccharomyces pombe, J. Cell Sci., 107 (1994), pp. 1197-1204.
2. Cueille, N.-Salimova, E.-Esteban, V.-Blanco, M.-Moreno, S.-Bueno, A.-Simanis, V., Flp1, a Fission Yeast Orthologue of the S. Cerevisiae CDC14 Gene, is not Required for Cyclin Degradation or Rum1p Stabilisation at the End of Mitosis, J. Cell Sci., 114 (2001), pp. 2649-2664.
3. 1 Cyclins, EMBO J., 15 (1996), pp. 850-860.
4. cdc2, Mol. Cell. Biol., 17 (1997), pp. 742-750.
5. Mitchison, J. M., Cell Cycle Growth and Periodicities, In Molecular Biology of the Fission Yeast, A. Nasim, P. Young, B. F. Johnson ed., Academic Press, New York, 1989, pp. 205-242.
6. + gene, Nature, 367 (1994), pp. 236-242.
7. Novak, B.- Pataki, Z.- Ciliberto, A.-Tyson, J. J., Mathematical Model of the Cell Division Cycle of Fission Yeast, Chaos, 11 (2001), pp. 277-286.
8. Nurse, P., Genetic Control of Cell Size at Cell Division in Yeast, Nature, 256 (1975), pp. 547-551.
9. Nurse, P.- Thuriaux, P.-Nasymth, K., Genetic Control of the Cell Division Cycle in the Fission Yeast Schizosaccharomyces pombe, Mol. Gen. Genet., 146 (1976), pp. 167-178.
10. + Functions as an Inducer in the Mitotic Control of Fission Yeast, Cell, 45 (1986), pp. 145-153.
11. +, a Gene Encoding a Protein Kinase Homolog, Cell, 49 (1987), pp. 559-567.
12. Stern, B.- Nurse, P., A Quantitative Model for the cdc2 Control of S Phase and Mitosis in Fission Yeast, Trends Genet., 12 (1996), pp. 345-350.
13. - cdc25Δ Mutant Cells, Proc. Natl. Acad. Sci. USA, 97 (2000), pp. 7865-7870.
14. Sveiczer, A.- Novák, B.- Mitchison, J. M., Mitotic Control in the Absence of cdc25 Mitotic Inducer in Fission Yeast, J. Cell Sci., 112 (1999), pp. 1085-1092.
15. Sveiczer, A.- Novak, B.- Mitchison, J. M., The Size Control of Fission Yeast Revisited, J. Cell Sci., 109 (1996), pp. 2947-2957.
16. Sveiczer, A.- Tyson, J.- Novák, B., Modelling the Fission Yeast Cell Cycle, Brief. Funct. Genom. Proteom., 2 (2004), pp. 298-307.
17. Trautmann, S.- Wolfe, B.- Jorgensen, P.- Tyers, M.- Gould, K. - McCollum, D., Fission Yeast Clp1p Phosphatase Regulates G2/M Transition and Coordination of Cytokinesis with Cell Cycle Progression, Curr. Biol., 11 (2001), pp. 931-940.
18. Tyson, J. J.: Modeling the Cell Division Cycle: cdc2 and cyclin interactions, Proc. Natl. Acad. Sci. USA, 88 (1991), pp. 7328-7332.
19. 1-specific Promoter of Mitotic Cyclin B Degradation, EMBO J., 19 (2000), pp. 3968-3977.