Brd2 is a TBP-associated protein and recruits TBP into E2F-1 transcriptional complex in response to serum stimulation

Molecular and Cellular Biochemistry

Volumn 294, Issue 1-2, 2007, Pages 45-54

  Peng, Jinhong ^a   Dong, Wei ^a   Chen, Lu ^a   Zou, Tingting ^a   Qi, Yipeng ^a   Liu, Yingle ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Brd2; E2F 1; Serum stimulation; TBP; Transcription activation

Indexed keywords

HISTONE ACETYLTRANSFERASE GCN5; LUCIFERASE; PROTEIN BRD2; TATA BINDING PROTEIN; TATA BINDING PROTEIN ASSOCIATED FACTOR; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL STIMULATION; CELL STRAIN 3T3; COMPLEX FORMATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSACTIVATION; TRANSCRIPTION INITIATION;

ANIMALS; E2F1 TRANSCRIPTION FACTOR; GENE DELETION; IMMUNOBLOTTING; MICE; NIH 3T3 CELLS; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SERUM; TATA-BOX BINDING PROTEIN; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TRANSFORMATION, GENETIC;

EID: 33846687297     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9223-6     Document Type: Article

References (28)

1. Berk AJ: Activation of RNA polymerase II transcription. Curr Opin Cell Biol 11: 330-335, 1999
2. Orphanides G, Lagrange T, Reinberg D: The general transcription factors of RNA polymerase II. Genes Dev 10: 2657-2683, 1996
3. Beverly ME: Specificity of gene regulation. Cell 109: 267-270, 2002
4. Lee TI, Young RA: Transcription of eukaryotic protein-coding genes. Annu Rev Genet 34: 77-137, 2000
5. Imbalzano AN, Kwon H, Green MR, Kingston RE: Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature 370: 481-485, 1994
6. Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996
7. Sylvester AM, Chen D, Krasinski K, Andres V: Role of c-fos and E2F in the induction of cyclin A transcription and vascular smooth muscle cell proliferation. J Clin Invest 101: 940-948, 1998
8. Lang SE, McMahon SB, Cole MD, Hearing P: E2F transcriptional activation requires TRRAP and GCN5 cofactors. J Biol Chem 276: 32627-32634, 2001
9. Denis GV, Vaziri C, Guo N, Faller DV: RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. Cell Grow Diff 11: 417-424, 2000
10. Guo N, Faller DV, Denis GV: Activation-induced nuclear translocation of RING3. J Cell Sci 113: 3085-3091, 2000
11. Greenwald RJ, Tumang JR, Sinha A, Currier N, Cardiff RD, Rothstein TL, Faller DV, Denis GV: Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia. Blood 103: 1475-1484, 2004
12. Chua P, Roeder GS: BDF1, a yeast chromosomal protein required for sporulation. Mol Cell Biol 15: 3685-3696, 1995
13. Matangkasombut O, Buratowski RM, Swilling NW, Buratowski S: Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. Genes Dev 14: 951-962, 2000
14. Sinha A, Faller DV, Denis GV: Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A. Biochem J 387: 257-269, 2005
15. Hudson BP, Martinez-Yamout MA, Dyson HJ, Wright PE: Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain. J Mol Biol 304: 355-370, 2000
16. Dhalluin C, Carlson J, Zeng L, He C, Aggarwal AK, Zhou MM: Structure and ligand of a histone acetyltransferase bromodomain. Nature 399: 491-496, 1999
17. Bannister AJ, Kouzarides T: The CBP co-activator is a histone acetyltransferase. Nature 384: 641-643, 1996
18. Mizzen CA, Yang XJ, Kokubo T, Brownell JE, Bannister AJ, Owen-Hughes T, Workman J, Wang L, Berger SL, Kouzarides T, Nakatani Y, Allis D: The TAF II 250 subunit of TFIID has histone acetyltransferase activity. Cell 87: 1261-1270, 1996
19. Ruppert S, Wang EH, Tjian R: CloningAand expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation. Nature 362: 175-179, 1993
20. Tamkun JW, Deuring R, Scott MP, Kissinger M, Pattatucci AM, Kaufman TC, Kennison JA: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68: 561-572, 1992
21. Winston F, Allis CD: The bromodomain: a chromatin-targeting module? Nat Struct Biol 6: 601-604, 1999
22. Crowley TE, Kaine EM, Yoshida M, Nandi A, Wolgemuth DJ: Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein. Mol Endocrinol 16: 1727-1737, 2002
23. Sterner DE, Grant PA, Roberts SM, Duggan LJ, Belotserkovskaya R, Pacella LA, Winston F, Workman JL, Berger SL: Functional organization of the yeast SAGA complex: Distinct components involved in structural integrity, nucleosome acetylation, and TATA-Binding Protein interaction. Mol Cell Biol 19: 86-98, 1999
24. Ornaghi P, Ballario P, Lena AM, Gonzalez A, Filetici P: The bromodomain of GCN5p interacts in vitro with specific residues in the N terminus of histone H4. J Mol Biol 287: 1-7, 1999
25. Poux AN, Marmorstein R: Molecular basis for GCN5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. Biochemistry 42: 14366-14374, 2003
26. Kimura A, Matsubara K, Horikoshi M: A decade of histone acetylation: marking eukaryotic chromosomes with specific codes. J Biochem 138: 647-662, 2005
27. Biswas D, Imbalzano AN, Eriksson P, Yu Y, Stillman DJ: Role for Nhp6, GCN5, and the Swi/Snf complex in stimulating formation of the TATA-Binding Protein-TFIIA-DNA complex. Mol Cell Biol 24: 8312-8321, 2004
28. Denis GV, McComb ME, Faller DV, Sinha A, Romesser PB, Costello CE: Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines. J Proteome Res 5: 502-511, 2006