Angina pectoris and ST-elevation after chemotherapy with 5-fluorouracil;Angina pectoris und ST-hebungen nach chemotherapie mit 5-FU

Internist

Volumn 48, Issue 1, 2007, Pages 69-74

  Spencker, S ^a   Schmittel, A ^a   Westermann, D ^a   Marek, A ^a   Schultheiss, H P ^a   Witzenbichler, B ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

5 Fluorouracil; Acute coronary syndrome; Cardiotoxicity; Coronary spasm

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CISPLATIN; DOCETAXEL; FLUOROURACIL; GLYCERYL TRINITRATE; NITRATE;

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CONTINUOUS INFUSION; CORONARY ARTERY; HEART INFARCTION; HUMAN; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; OROPHARYNX CARCINOMA; SIDE EFFECT; SQUAMOUS CELL CARCINOMA; ST SEGMENT ELEVATION; THORAX PAIN;

ACUTE CORONARY SYNDROME; AGED; ANGINA PECTORIS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; CORONARY ANGIOGRAPHY; CORONARY VASOSPASM; DIAGNOSIS, DIFFERENTIAL; ELECTROCARDIOGRAPHY; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; MALE; NEOPLASMS, UNKNOWN PRIMARY; NITROGLYCERIN; OROPHARYNGEAL NEOPLASMS; RADIOTHERAPY, ADJUVANT; VASODILATOR AGENTS;

EID: 33846645916     PISSN: 00209554     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00108-006-1750-4     Document Type: Article

References (14)

1. Alter P, Herzum M, Schaefer JR et al. (2005) Coronary artery spasm induced by 5-fluorouracil. Z Kardiol 94: 33-37
2. Anand AJ (1994) Fluorouracil cardiotoxicity. Ann Pharmacother 28: 374-378
3. Becker K, Erckenbrecht JF, Haussinger D et al. (1999) Cardiotoxicity of the antiproliferative compound fluorouracil. Drugs 57: 475-484
4. Forni M de, Malet-Martino MC, Jaillais P et al. (1992) Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study. J Clin Oncol 10: 1795-1801
5. Gradishar WJ, Vokes EE (1990) 5-Fluorouracil cardiotoxicity: a critical review. Ann Oncol 1: 409-414
6. Jensen SA, Sorensen JB (2006) Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine. Cancer Chemother Pharmacol 58: 487-493
7. Keefe DL, Roistacher N, Pierri MK (1993) Clinical cardiotoxicity of 5-fluorouracil. J Clin Pharmacol 33: 1060-1070
8. Lieutaud T, Brain E, Golgran-Toledano D et al. (1996) 5-Fluorouracil cardiotoxicity: a unique mechanism for ischaemic cardiopathy and cardiac failure? Eur J Cancer 32A: 368-369
9. Mosseri M, Fingert HJ, Varticovski L et al. (1993) In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle. Cancer Res 53: 3028-3033
10. Schannwell CM, Steiner S, Strauer BE (2005) Hypertensive microvaskuläre Erkrankung. Herz 30: 26-36
11. Schimmel KJ, Richel DJ, van den Brink RB et al. (2004) Cardiotoxicity of cytotoxic drugs. Cancer Treat Rev 30: 181-191
12. Sobrero AF, Aschele C, Bertino JR (1997) Fluorouracil in colorectal cancer - a tale of two drugs: implications for biochemical modulation. J Clin Oncol 15: 368-381
13. Tsavaris N, Kosmas C, Vadiaka M et al. (2002) Cardiotoxicity following different doses and schedules of 5-fluorouracil administration for malignancy - a survey of 427 patients. Med Sci Monit 8: PI51-57
14. Wacker A, Lersch C, Scherpinski U et al. (2003) High incidence of angina pectoris in patients treated with 5-fluorouracil: a planned surveillance study with 102 patients. Oncology 65: 108-112