Radiation-induced production of PAR-1 and TGF-beta 1 mRNA in lung of C57Bl6 and C3H murine strains and influence of pharmacoprophylaxis by ACE inhibitors

Pathology Research and Practice

Volumn 203, Issue 2, 2007, Pages 107-114

  Matěj, Radoslav ^a   Housa, Daniel ^b   Poučková, Pavla ^c   Zadinová, Marie ^c   Olejár, Tomáš ^c  

^a FAKULTNÍ THOMAYEROVA NEMOCNICE   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

ACE inhibitor; PAR 1; Radiation injury; TGF 1

Indexed keywords

BUTYLAMINIPERINDOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C3H MOUSE; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; FEMALE; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; LUNG PARENCHYMA; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; STRAIN DIFFERENCE;

EID: 33846645546     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2006.10.006     Document Type: Article

References (27)

1. Anderson B., Khaper N., Dhalla A.K., et al. Anti-free radical mechanisms in captopril protection against reperfusion injury in isolated rat hearts. Can. J. Cardiol. 12 (1996) 1099-1104
2. Barry G.D., Le G.T., and Fairlie D.P. Agonists and antagonists of protease activated receptors (PARs). Curr. Med. Chem. 13 (2006) 243-265
3. Bright J.J., and Sriram S. TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes. J. Immunol. 161 (1998) 1772-1777
4. Coggle J.E. Proliferation of type II pneumonocytes after X-irradiation. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 51 (1987) 393-399
5. Coggle J.E., Lambert B.E., and Moores S.R. Radiation effects in the lung. Environ. Health Perspect. 70 (1986) 261-291
6. Gillette S.M., Powers B.E., Orton E.C., et al. Early radiation response of the canine heart and lung. Radiat. Res. 125 (1991) 34-40
7. Grande J., Melder D., Zinsmeister A., et al. Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells. Lab. Invest. 69 (1993) 387-395
8. Grande J.P. Role of transforming growth factor-beta in tissue injury and repair. Proc. Soc. Exp. Biol. Med. 214 (1997) 27-40
9. Haston C.K., and Travis E.L. Murine susceptibility to radiation-induced pulmonary fibrosis is influenced by a genetic factor implicated in susceptibility to bleomycin-induced pulmonary fibrosis. Cancer Res. 57 (1997) 5286-5291
10. Hill R.P. Radiation effects on the respiratory system. BJR Suppl. 27 (2005) 75-81
11. Hollenberg M.D., and Houle S. Proteinases as hormone-like signal messengers. Swiss Med. Wkly. 135 (2005) 425-432
12. Howell D.C., Johns R.H., Lasky J.A., et al. Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis. Am. J. Pathol. 166 (2005) 1353-1365
13. Kantak S.S., Diglio C.A., and Onoda J.M. Low dose radiation-induced endothelial cell retraction. Int. J. Radiat. Biol. 64 (1993) 319-328
14. Kutz S.M., Higgins C.E., Samarakoon R., et al. TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling. Exp. Cell Res. 312 (2006) 1093-1105
15. Malygin A.M., Meri S., and Timonen T. Regulation of natural killer cell activity by transforming growth factor-beta and prostaglandin E2. Scand. J. Immunol. 37 (1993) 71-76
16. Matrisian L.M., Ganser G.L., Kerr L.D., et al. Negative regulation of gene expression by TGF-beta. Mol. Reprod. Dev. 32 (1992) 111-120
17. Mauviel A. Transforming growth factor-beta: a key mediator of fibrosis. Methods Mol. Med. 117 (2005) 69-80
18. Moulder J.E. Pharmacological intervention to prevent or ameliorate chronic radiation injuries. Semin. Radiat. Oncol. 13 (2003) 73-84
19. Nguyen L., Ward W.F., Ts'ao C.H., et al. Captopril inhibits proliferation of human lung fibroblasts in culture: a potential antifibrotic mechanism. Proc. Soc. Exp. Biol. Med. 205 (1994) 80-84
20. Oikawa T., Freeman M., Lo W., et al. Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition. Kidney Int. 51 (1997) 164-172
21. Steinhoff M., Buddenkotte J., Shpacovitch V., et al. Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr. Rev. 26 (2005) 1-43
22. Wang J., Zheng H., Ou X., et al. Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Am. J. Pathol. 160 (2002) 2063-2072
23. Wang Q., Pfeiffer II G.R., Stevens T., et al. Lung microvascular and arterial endothelial cells differ in their responses to intercellular adhesion molecule-1 ligation. Am. J. Respir. Crit. Care Med. 166 (2002) 872-877
24. Ward W.F., Lin P.J., Wong P.S., et al. Radiation pneumonitis in rats and its modification by the angiotensin-converting enzyme inhibitor captopril evaluated by high-resolution computed tomography. Radiat. Res. 135 (1993) 81-87
25. Ward W.F., Molteni A., Ts'ao C.H., et al. Captopril reduces collagen and mast cell accumulation in irradiated rat lung. Int. J. Radiat. Oncol. Biol. Phys. 19 (1990) 1405-1409
26. Ward W.F., Molteni A., Ts'ao C.H., et al. Radiation pneumotoxicity in rats: modification by inhibitors of angiotensin converting enzyme. Int. J. Radiat. Oncol. Biol. Phys. 22 (1992) 623-625
27. Waters C.M., Taylor J.M., Molteni A., et al. Dose-response effects of radiation on the permeability of endothelial cells in culture. Radiat. Res. 146 (1996) 321-328