HPLC determination of chlorhexidine gluconate and p-chloroaniline in topical ointment

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 3, 2007, Pages 1169-1173

  Havlikova L ^a   Matysova L ^a   Novakova L ^a   Hajkova R ^a   Solich, P ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Chlorhexidine; HPLC; Ointment

Indexed keywords

4 CHLOROANILINE; CHLORHEXIDINE GLUCONATE; DRUG METABOLITE; ETHYL PARABEN;

ARTICLE; COLUMN; DEVICE; DRUG DETERMINATION; DRUG FORMULATION; DRUG QUALITY; FLOW RATE; OINTMENT; PH MEASUREMENT; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION;

ACETONITRILES; ADMINISTRATION, TOPICAL; ANILINE COMPOUNDS; BUFFERS; CHLORHEXIDINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; OINTMENTS; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET; VETERINARY DRUGS;

EID: 33846634990     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.09.037     Document Type: Article

References (29)

1. USP 29-NF 24 United States Pharmacopoeial Convention Inc., 2006.
2. http://www.uhe.com/chlorhex.htm, April 2006.
3. http://www.emea.eu.int/pdfs/vet/mrls/010796en.pdf, April 2006.
4. http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/191804.htm, April 2006.
5. Richard A., Elbaz M., and Andermann G. J. Chromatogr. 298 (1984) 356-359
6. Yue C., Poff J., Cortés M.E., Sinisterra R.D., Faris C.B., Hildgen P., Langer R., and Shastri V.P. Biomaterials 25 (2004) 3743-3750
7. Medlicott N.J., Tucker I.G., Rathbone M.J., Holborow D.W., and Jones D.S. Int. J. Pharm. 143 (1996) 25-35
8. Pesonen T., Holmalahti J., and Pohjola J. J. Chromatogr. B: Biomed. Appl. 665 (1995) 222-225
9. Lam Y.W.F., Chan D.C.N., Rodriguez S.Y., Lintakoon J.H., and Lam T.H. J. Chromatogr.: Biomed. Appl. 612 (1993) 166-171
10. Bauer M., Degude C., and Mailhe L. J. Chromatogr. 315 (1984) 457-464
11. Wyhowski-Bukanski B., and Masse M.O. Int. J. Cosmet. Sci. 6 (1984) 283-291
12. Gagliari L., et al. J. Chromatogr. 348 (1985) 321-326
13. Izumoto S., Machida Y., Hiroyuki N., Nakamura K., Nakai H., and Sato T. J. Pharm. Biomed. Anal. 15 (1997) 1457-1466
14. Ha Y., and Cheung A.P. J. Pharm. Biomed. Anal. 14 (1996) 1327-1334
15. Doub W.H., et al. J. AOAC Int. 79 (1996) 636-639
16. Gavlick W.K. J. Chromatogr. A 623 (1992) 375-380
17. Below H., Lehan N., and Kamer A. Microchim. Acta 146 (2004) 129-135
18. Brougham L.R., Cheng H., and Pitman K.A. J. Chromatogr. B. 383 (1986) 365-437
19. Wainwright P., and Cooke M. Analyst 111 (1986) 1343-1344
20. Kudo K., Ikeda N., Kiyoshima A., Hino Y., Nishida N., and Inoue N. J. Anal. Toxicol. 26 (2002) 119-122
21. Medlicott N.J., Ferry D.G., Tucker I.G., Rathborne M.J., Holborow D.W., and Jones D.S. J. Liq. Chromatogr. 17 (1994) 1605-1620
22. Cheung A.P., Mavar R., Carlson C., and Chiang W.K. J. Pharm. Biomed. Anal. 9 (1991) 41-45
23. Ji X.F., Yu K.Y., and Zhang W. Yaowu-Fenxi-Zazhi 17 (1996) 363-365
24. Xu Y.M., and Wong G.Y. J. Liq. Chromatogr. Relat. Technol. 22 (1999) 2071-2091
25. Marengo E., Gianotti V., Angioi S., and Gennaro M.C. J. Chromatogr. A 1029 (2004) 57-65
26. Musteata F.M., and Pawliszyn J. J. Pharm. Biomed. Anal. 37 (2005) 1015-1024
27. Usui K., Hishinuma T., Yamaguchi H., Tachiiri N., and Goto J. J. Chromatogr. B 831 (2006) 105-109
28. Zhang D., Liang H., Zeng J., and Rao G. J. West China Univer. Med. Sci. 26 (1995) 447-451
29. http://www.ich.org/LOB/media/MEDIA417.pdf, April 2006.