Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer

Annals of Surgical Oncology

Volumn 14, Issue 2, 2007, Pages 462-469

  Baik, Seung Hyuk ^a   Kim, Nam Kyu ^a,b   Lee, Young Chan ^a   Kim, Hoguen ^a   Lee, Kang Young ^a   Sohn, Seung Kook ^a   Cho, Chang Hwan ^a  

^a Yonsei University   (South Korea)

^b NONE   (South Korea)

Author keywords

Adjuvant chemoradiotherapy; Circumferential resection margin; Rectal cancer; Total mesorectal excision

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PROGNOSIS; RADIATION DOSE; RECTUM CANCER; RECTUM RESECTION; STATISTICAL SIGNIFICANCE; TOTAL MESORECTAL EXCISION; TREATMENT OUTCOME;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOPSY; CHEMOTHERAPY, ADJUVANT; COLECTOMY; FEMALE; FLUOROURACIL; HUMANS; LEUCOVORIN; MALE; MIDDLE AGED; PROGNOSIS; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RECTUM; SURVIVAL ANALYSIS;

EID: 33846626834     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-006-9171-0     Document Type: Article

References (28)

1. Nymann T, Jess P, Christiansen J. Rate and treatment of pelvic recurrence after abdominoperineal resection and low anterior resection for rectal cancer. Dis Colon Rectum 1995; 38:799-802.
2. Pilipshen SJ, Heilweil M, Quan SH, Sternberg SS, Enker WE. Patterns of pelvic recurrence following definitive resections of rectal cancer. Cancer 1984; 53:1354-62.
3. Pahlman L, Glimelius B. Local recurrences after surgical treatment for rectal carcinoma. Acta Chir Scand 1984; 150:331-5.
4. Heald RJ. A new approach to rectal cancer. Br J Hosp Med 1979; 22:277-81.
5. Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1987-1997. Arch Surg 1998; 133:894-9.
6. Enker WE, Thaler HT, Cranor ML, Polyak T. Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg 1995; 181:335-46.
7. Heald RJ, Ryall RD. Recurrence, survival after total mesorectal excision for rectal cancer. Lancet 1986; I:1479-82.
8. Heald RJ, Husband EM, Ryall RD. The mesorectum in rectal cancer surgery - the clue to pelvic recurrence?. Br J Surg 1982; 69:613-6.
9. Frykholm GJ, Glimelius B, Pahlman L. Preoperative or postoperative irradiation in adenocarcinoma of the rectum: final treatment results of a randomized trial and an evaluation of late secondary effects. Dis Colon Rectum 1993; 36:564-72.
10. Treurniet-Donker AD, van Putten WL, Wereldsma JC, et al. Postoperative radiation therapy for rectal cancer. An interim analysis of a prospective, randomized multicenter trial in The Netherlands. Cancer 1991; 67:2042-8.
11. Birbeck KF, Macklin CP, Tiffin NJ, et al. Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg 2002; 235:449-57.
12. Cawthorn SJ, Parums DV, Gibbs NM, A'Hern RP, Caffarey SM, Broughton CI, Marks CG. Extent of mesorectal spread and involvement of lateral resection margin as prognostic factors after surgery for rectal cancer. Lancet 1990; 335:1055-9.
13. Wibe A, Rendedal PR, Svensson E, Norstein J, Eide TJ, Myrvold HE, Soreide O. Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 2003; 89:327-34.
14. Marijnen CA, Nagtegaal ID, Kapiteijn E, et al. Radotherapy does not compensate for positive resection margin in rectal cancer patients: report of a multicenter radomized trial. Int J Radiat Oncol Biol Phys 2003; 55:1311-20.
15. Greene FL, Page DL, Fleming ID, et al. AJCC cancer staging manual6 New York: Springer-Verlag; 2002.
16. NIH consensus conference adjuvant therapy for patients with colon and rectal cancer. JAMA 1990; 264:1444-50.
17. Quirke P, Durdey P, Dixon MF, Williams NS. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection: histopathological study of lateral tumor spread and surgical excision. Lancet 1986; 2:996-9.
18. Adam IJ, Mohamdee MO, Martin IG, et al. Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 1994; 344:701-11.
19. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for respectable rectal cancer. N Engl J Med 2001; 345:638-6.
20. Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351:1731-40.
21. Wiggers T, van de Velde CJ. The circumferential margin in rectal cancer: recommendations based on the Dutch Total Mesorectal Excision Study. Eur J Cancer 2002; 38:973-6.
22. Compton C, Fenoglio-Preiser CM, Pettigrew N, Fielding LP. American Joint Committee on Cancer prognostic factors consensus conference: colorectal working group. Cancer 2000; 88:1739-57.
23. Nagtegaal ID, Marijnen CA, Kranenbarg EK, van de Velde CJ, van Krieken JHPathology Review Committee; Cooperative Clinical Investigators Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. Am J Surg Pathol 2002; 26:350-7.
24. Zhu AX, Willett CG. Combined modality treatment for rectal cancer. Semin Oncol 2005; 32:103-12.
25. Kim NK, Kim MJ, Park JK, Park SI, Min JS. Preoperative staging of rectal cancer with MRI: accuracy and clinical usefulness. Ann Surg Oncol 2000; 7:732-7.
26. Martling A, Holm T, Bremmer S, Lindholm J, Cedermark B, Blomqvist L. Prognostic value of preoperative magnetic resonance imaging of the pelvis in rectal cancer. Br J Surg 2003; 90:1422-8.
27. Beets-Tan RG. MRI in rectal cancer: the T stage and circumferential resection margin. Colorectal Dis 2003; 5:392-5.
28. Beets-Tan RG, Beets GL, Vliegen RF, et al. Accuracy of magnetic resonance imaging in rectal cancer surgery. Lancet 2001; 357:497-504.