Effects of recombined human neuregulin on the contractibility of cardiac muscles of rhesus monkeys with pacing-induced heart failure

Journal of Sichuan University (Medical Science)

Volumn 38, Issue 1, 2007, Pages 105-108

  Li, Jiang ^a   Gu, Xing Hua ^a   Duan, Jia Chuan ^a   Zeng, Li ^a   Li, You ^a   Wang, Li ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Gene expression; Heart failure; Hemodynamics; Myosin heavy chain; Neuregulin

Indexed keywords

MESSENGER RNA; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN ALPHA; NEU DIFFERENTIATION FACTOR; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; HEART FAILURE; HEART MUSCLE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; MUSCLE CONTRACTILITY; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RHESUS MONKEY;

EID: 33846588522     PISSN: 1672173X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Sawyer DB, Zuppinger C, Miller TA, et al. Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation. 2002;105(13):1551-1554.
2. -ΔΔCt method. Methods (Duluth), 2001;25(4):402-408.
3. Zhao YY, Sawyer DR, Baliga RR, et al. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem, 1998;273(17):10261-10269.
4. Rohrbach S, Yan X, Weinberg EO, et al. Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors. Circulation, 1999;100(4):407-412.
5. Baliga RR, Pimental DR, Zhao YY, et al. NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK. American Journal of Physiology, 1999; 277(5 Pt 2):H2026-2037.