Molecular analysis of fibulin-5 function during De Novo synthesis of elastic fibers

Molecular and Cellular Biology

Volumn 27, Issue 3, 2007, Pages 1083-1095

  Zheng, Qian ^a   Davis, Elaine C ^b   Richardson, James A ^a   Starcher, Barry C ^c   Li, Tiansen ^d   Gerard, Robert D ^a   Yanagisawa, Hiromi ^a,e  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^d MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CALCIUM BINDING PROTEIN; ELASTIN; EPIDERMAL GROWTH FACTOR; FIBULIN 5; MUTANT PROTEIN; SCAFFOLD PROTEIN;

ADENOVIRUS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM BINDING; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL INTERACTION; CONTROLLED STUDY; ELASTIC FIBER; EMBRYO; EXTRACELLULAR MATRIX; FUNCTIONAL PROTEOMICS; IN VIVO STUDY; MOLECULAR DYNAMICS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SKIN; STRUCTURAL PROTEOMICS; TISSUE REPAIR; TISSUE STRUCTURE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; CERCOPITHECUS AETHIOPS; CHO CELLS; CHONDROCYTES; COS CELLS; CRICETINAE; CRICETULUS; DERMIS; ELASTIC TISSUE; ELASTICITY; ELASTIN; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; GENE TRANSFER TECHNIQUES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SOLUBILITY;

ADENOVIRIDAE; MUS;

EID: 33846576176     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01330-06     Document Type: Article

References (39)

1. Aoki, K., C. Barker, X. Danthinne, M. J. Imperiale, and G. J. Nabel. 1999. Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro. Mol. Med. 5:224-231.
2. Argraves, W. S., L. M. Greene, M. A. Cooley, and W. M. Gallagher. 2003. Fibulins: physiological and disease perspectives. EMBO Rep. 4:1127-1131.
3. Broekelmann, T. J., B. A. Kozel, H. Ishibashi, C. C. Werneck, F. W. Keeley, L. Zhang, and R. P. Mecham. 2005. Tropoelastin interacts with cell-surface glycosaminoglycans via its COOH-terminal domain. J. Biol. Chem. 280:40939-40947.
4. Carta, L., L. Pereira, E. Arteaga-Solis, S. Y. Lee-Arteaga, B. Lenart, B. Starcher, C. A. Merkel, M. Sukoyan, A. Kerkis, N. Hazeki, D. R. Keene, L. Y. Sakai, and F. Ramirez. 2006. Fibrillins 1 and 2 plerform partially overlapping functions during aortic development. J. Biol. Chem. 281:8016-8023.
5. Cox, B. A., B. C. Starcher, and D. W. Urry. 1974. Communication: coacervation of tropoelastin results in fiber formation. J. Biol. Chem. 249:997-998.
6. Czirok, A., J. Zach, B. A. Kozel, R. P. Mecham, E. C. Davis, and B. J. Rongish. 2006. Elastic fiber macro-assembly is a hierarchical, cell motion-mediated process. J. Cell Physiol. 207:97-106.
7. Reference deleted.
8. Doliana, R., M. Mongiat, F. Bucciotti, E. Giacomello, R. Deutzmann, D. Volpin, G. M. Bressan, and A. Colombatti. 1999. EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins. J. Biol. Chem. 274:16773-16781.
9. Elahi, E., R. Kalhor, S. S. Banihosseini, N. Torabi, H. Pour-Jafari, M. Houshmand, S. S. Amini, A. Ramezani, and B. Loeys. 2006. Homozygous missense mutation in fibulin-5 in an Iranian autosomal recessive cutis laxa pedigree and associated haplotype. J. Investig. Dermatol. 126:1506-1509.
10. Freeman, L. J., A. Lomas, N. Hodson, M. J. Sherratt, K. T. Mellody, A. S. Weiss, A. Shuttleworth, and C. M. Kielty. 2005. Fibulin-5 interacts with fibrillin-1 molecules and microfibrils. Biochem. J. 388:1-5.
11. Gerard, R. D., and R. S. Meidell. 1995. Adenovirus vectors, p. 285-307. In B. D. Hames and D. Glover (ed.), DNA cloning-a practical approach: mammalian systems. Oxford University Press. Oxford, United Kingdom.
12. Hanssen, E., F. H. Hew, E. Moore, and M. A. Gibson. 2004. MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils. J. Biol. Chem. 279:29185-29194.
13. Hayashi, K., K. S. Fong, F. Mercier, C. D. Boyd, K. Csiszar, and M. Hayashi. 2004. Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues. J. Mol. Histol. 35:845-855.
14. Reference deleted.
15. Reference deleted.
16. Kielty, C. M., M. J. Sherratt, and C. A. Shuttleworth. 2002. Elastic fibres. J. Cell Sci. 115:2817-2828.
17. Kozel, B. A., B. J. Rongish, A. Czirok, J. Zach, C. D. Little, E. C. Davis, R. H. Knutsen, J. E. Wagenseil, M. A. Levy, and R. P. Mecham. 2006. Elastic fiber formation: a dynamic view of extracellular matrix assembly using timer reporters. J. Cell Physiol. 207:87-96.
18. Liu, X., Y. Zhao, J. Gao, B. Pawlyk, B. Starcher, J. A. Spencer, H. Yanagisawa, J. Zuo, and T. Li. 2004. Elastic fiber homeostasis requires lysyl oxidase-like 1 protein. Nat. Genet. 36:178-182.
19. Loeys, B., L. Van Maldergem, G. Mortier, P. Coucke, S. Gerniers, J. M. Naeyaert, and A. De Paepe. 2002. Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa. Hum. Mol. Genet. 11:2113-2118.
20. Markova, D., Y. Zou, F. Ringpfeil, T. Sasaki, G. Kostka, R. Timpl, J. Uitto, and M. L. Chu. 2003. Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. Am. J. Hum. Genet. 72:998-1004.
21. Maurer, P., and E. Hohenester. 1997. Structural and functional aspects of calcium binding in extracellular matrix proteins. Matrix Biol. 15:569-580; discussion, 581.
22. McLaughlin, P. J., Q. Chen, M. Horiguchi, B. C. Starcher, J. B. Stanton, T. J. Broekelmann, A. D. Marmorstein, B. McKay, R Mecham, T. Nakamura, and L. Y. Marmorstein. 2006. Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol. Cell. Biol. 26:1700-1709.
23. Mecham, R. P., and E. C. Davis. 1994. Elastic fiber structure and assembly, p. 281-314. In P. D. Yurchenco, D. E. Birk, and R. P. Mecham (ed.), Extracellular matrix assembly and structure. Academic Press, New York, NY.
24. Mochizuki, S., B. Brassart, and A. Hinek. 2002. Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells. J. Biol. Chem. 277:44854-44863.
25. Nakamura, T., P. R. Lozano, Y. Ikeda, Y. Iwanaga, A. Hinek, S. Minamisawa, C. F. Cheng, K. Kobuke, N. Dalton, Y. Takada, K. Tashiro, J. Ross, Jr., T. Honjo, and K. R. Chien. 2002. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 415:171-175.
26. Nakamura, T., P. Ruiz-Lozano, V. Lindner, D. Yabe, M. Taniwaki, Y. Furukawa, K. Kobuke, K. Tashiro, Z. Lu, N. L. Andon, R. Schaub, A. Matsumori, S. Sasayama, K. R. Chien, and T. Honjo. 1999. DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. J. Biol. Chem. 274:22476-22483.
27. Reinhardt, D. P., D. R. Keene, G. M. Corson, E. Poschl, H. P. Bachinger, J. E. Gambee, and L. Y. Sakai. 1996. Fibrillin-1: organization in microfibrils and structural properties. J. Mol. Biol. 258:104-116.
28. Robb, B. W., H. Wachi, T. Schaub, R. P. Mecham, and E. C. Davis. 1999. Characterization of an in vitro model of elastic fiber assembly. Mol. Biol. Cell 10:3595-3605.
29. Rodgers, U. R., and A. S. Weiss. 2004. Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin. Biochimie 86:173-178.
30. Sasaki, T., W. Gohring, N. Miosge, W. R. Abrams, J. Rosenbloom, and R. Timpl. 1999. Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins. FEBS Lett. 460:280-284.
31. Sasaki, T., K. Mann, H. Wiedemann, W. Gohring, A. Lustig, J. Engel, M. L. Chu, and R. Timpl. 1997. Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge. EMBO J. 16:3035-3043.
32. Setoguchi, Y., H. A. Jaffe, C. Danel, and R. G. Crystal. 1994. Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors. J. Investig. Dermatol. 102:415-421.
33. Spencer, J. A., S. L. Hacker, E. C. Davis, R. P. Mecham, R. H. Knutsen, D. Y. Li, R. D. Gerard, J. A. Richardson, E. N. Olson, and H. Yanagisawa. 2005. Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration. Proc. Natl. Acad. Sci. USA 102:2946-2951.
34. Starcher, B., and M. Conrad. 1995. A role for neutrophil elastase in the progression of solar elastosis. Connect. Tissue Res. 31:133-140.
35. Thomassin, L., C. C. Werneck, T. J. Broekelmann, C. Gleyzal, I. K. Hornstra, R. P. Mecham, and P. Sommer. 2005. The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers. J. Biol. Chem. 280:42848-42855.
36. Timpl, R., T. Sasaki, G. Kostka, and M. L. Chu. 2003. Fibulins: a versatile family of extracellular matrix proteins. Nat. Rev. Mol. Cell Biol. 4:479-489.
37. Vrhovski, B., S. Jensen, and A. S. Weiss. 1997. Coacervation characteristics of recombinant human tropoelastin. Eur. J. Biochem. 250:92-98.
38. Werneck, C. C., B. C. Trask, T. J. Broekelmann, T. M. Trask, T. M. Ritty, F. Segade, and R. P. Mecham. 2004. Identification of a major microfibril-associated glycoprotein-1-binding domain in fibrillin-2. J. Biol. Chem. 279:23045-23051.
39. Yanagisawa, H., E. C. Davis, B. C. Starcher, T. Ouchi, M. Yanagisawa, J. A. Richardson, and E. N. Olson. 2002. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature 415:168-171.