Mechanisms of immunotherapy in allergic rhinitis

Biomedicine and Pharmacotherapy

Volumn 61, Issue 1, 2007, Pages 29-33

  Jayasekera, Nivenka P ^a   Toma, Tudor P ^a   Williams, Andrew ^a   Rajakulasingam, K ^a  

^a HOMERTON UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Allergic rhinitis; Specific immunotherapy (SIT)

Indexed keywords

ALLERGEN; ANTIHISTAMINIC AGENT; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G4 ANTIBODY; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 5; LEUKOTRIENE RECEPTOR BLOCKING AGENT; STEROID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLERGENICITY; ALLERGIC ASTHMA; ALLERGIC REACTION; ALLERGIC RHINITIS; ANTIBODY PRODUCTION; ANTIGEN PRESENTING CELL; ARTICLE; BASOPHIL; CD4+ CD25+ T LYMPHOCYTE; CELLULAR IMMUNITY; DELAYED HYPERSENSITIVITY; DRUG EFFICACY; EFFECTOR CELL; EOSINOPHIL; HELPER CELL; HUMAN; HUMORAL IMMUNITY; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOTHERAPY; LEUKOCYTE MIGRATION; NOSE MUCOSA; NOSE SECRETION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SENSITIZATION; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOTHERAPY; MODELS, IMMUNOLOGICAL; RHINITIS, ALLERGIC, SEASONAL; T-LYMPHOCYTES;

EID: 33846569413     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2006.09.013     Document Type: Article

References (30)

1. Allergy UK. Night and day every day report. June 2005.
2. Durham S.R. Allergen immunotherapy (desensitisation) for allergic diseases. Clin Med 6 4 (2006) 348-351
3. Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology. Allergy 55 2 (2000) 116-134
4. Rajakulasingam K., and Durham S.R. Comparative pathogenesis of the upper and lower airway allergic disease. In: Corren J., Togias A., and Bousquet J. (Eds). Upper and lower respiratory disease (2003), Marcel Dekker 139-158
5. Howarth P.H., Rajakulasingam K., and Feather I.H. Mediators and allergic rhinitis. Clin Exp Allergy 21 1 (1991) 262-266
6. Howarth P.H., Wilson S., Lau L., and Rajakulasingam K. The nasal mast cell and rhinitis. Clin Exp Allergy 21 2 (1991) 3-8
7. Frew A.J., Powell R.J., Corrigan C.J., and Durham S.R. Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment- resistant seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 117 (2006) 319-325
8. Moller C., Dreborg S., Ferdousi H.A., Halken S., Host A., Jacobson L., et al. Pollen immunotherapy reduced the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-Study). J Allergy Clin Immunol (2002) 251-256
9. Cooke R.A., Barnard J.H., Hebald S., and Stull A. Serelogic evidence of immunity with coexisting sensitization in a type of human allergy (hay fever). J Exp Med 62 (1935) 733-750
10. Loveless M.H. Immunological studies of pollinosis IV: The relationship between thermostable antibody in the circulation and clinical immunity. J Immunol 47 (1943) 165-180
11. Lichtenstein L.M., Holtzman N.A., and Burnette L.S. A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody. J Immunol 101 (1968) 317-324
12. Norman P.S. Immunotherapy. Prog Allergy 32 (1982) 318-346
13. Peng Z., Naclerio R.M., Norman P.S., and Adkinson Jr. N.F. Quantitative IgE and IgG subclass responses during and after long-term ragweed immunotherapy. J Allergy Clin Immunol 9 (1992) 519-529
14. Durham S.R., and Till S.J. Immunologic changes associated with allergen immunotherapy. J Allergy Clin Immunol 102 (1998) 157-164
15. Nanda A., O'Connor M., Anand M., Drskin S.C., Zhang L., Hines B., et al. Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract. J Allergy Clin Immunol 114 (2004) 1339-1344
16. Lichtenstein L.M., Ishizaka K., Norman P.S., Sobotka A.K., and Hill B.M. IgE antibody measurements in ragweed hay fever: relationship to clinical severity and the results of immunotherapy. J Clin Invest 52 (1973) 472-482
17. Ito H., Suzuki M., Mamiya S., Takagi I., and Baba S. Study on changes in the level of serum IL4 and soluble CD23 (s-CD23) with immunotherapy in nasal allergy patients. Acta Otolaryngol (Stockh) 525 (1996) 98-104
18. Kljaic-Turkalj M., Cvoriscec B., Tudoric N., Stipic-Markovic A., Rabatic S., Trescec A., et al. Decrease in CD23+B lymphocytes and clinical outcome in asthmatic patients receiving specific rush immunotherapy. Int Arch Allergy Immunol 111 (1996) 188-194
19. Platts-Mills T.A.E., Von Maur R.K., Ishizaka K., Norman P.S., and Lichtenstein L.M. IgA and IgG anti-ragweed antibodies in nasal secretions. J Clin Invest 57 (1976) 1041-1050
20. 2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro. J Clin Invest 98 (1996) 1676-1683
21. Michils A., Baldassarre S., Ledent C., Mairesse M., Gossart B., and Duchateau J. Early effect of ultrarush venom immunotherapy on the IgG antibody response. Allergy 55 (2000) 455-462
22. Furin M.J., Norman P.S., Creticos P.S., Proud D., Kagey-Sobotka A., Lichtenstein L.M., et al. Immunotherapy decreases antigen induced eosinophil migration into the nasal cavity. J Allergy Clin Immunol 88 (1991) 27-32
23. Majchel A.M., Proud D., Freidhoff L., Creticos P.S., Norman P.S., and Naclerio R.M. The nasal response to histamine challenge: effect of the pollen season and immunotherapy. J Allergy Clin Immunol 90 (1992) 85-91
24. Lichtenstein L.M., Norman P.S., Winkenwerder W.L., and Osler A.G. In vitro studies of human ragweed allergy: changes in cellular and humoral activity associated with specific desensitization. J Clin Invest 45 (1966) 1126-1136
25. Brunet C., Bedart P.M., Lavoie A., Jobin M., and Hebert J. Allergic rhinitis to ragweed pollen I. Reassessment of the effects of immunotherapy on cellular and hormonal responses. J Allergy Clin Immunol 89 (1992) 76-86
26. Creticos P.S., Adkinson N.F., Kagey-Sobotka A., Proud D., Meier H.L., Naclerio R.M., et al. Nasal challenge with ragweed pollen in hay fever patients: effect of immunotherapy. J Clin Invest 76 (1985) 2247-2253
27. Till S.J., Francis J.N., Nouri-Aria K., and Durham S.R. Mechanisms of immunotherapy. J Allergy Clin Immunol 113 (2004) 1025-1034
28. Izcue A., Coombes J.L., and Powrie F. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol Rev 212 (2006) 256-271
29. Stock P., DeKruyff R.H., and Umetsu D.T. Inhibition of the allergic response by regulatory T cells. Curr Opin Allergy Clin Immunol 6 (2006) 12-16
30. Bach J.F. Regulatory T cells under scrutiny. Nat Rev Immunol 3 (2003) 189-198