Dynamic lung mechanics in late-stage emphysema before and after lung volume reduction surgery

Respiratory Physiology and Neurobiology

Volumn 155, Issue 3, 2007, Pages 234-242

  Henderson, A Cortney ^a   Ingenito, Edward P ^b   Salcedo, Edgardo S ^a   Moy, Marilyn L ^b   Reilly, John J ^b   Lutchen, Kenneth R ^a  

^a Boston University   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Chronic obstructive pulmonary disease; Heterogeneity; Inspiratory lung elastance; Inspiratory lung impedance; Inspiratory lung resistance

Indexed keywords

ADULT; AGED; AIRWAY CONSTRICTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DISEASE SEVERITY; EMPHYSEMA; FEMALE; GENETIC HETEROGENEITY; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; LUNG FUNCTION TEST; LUNG MECHANICS; LUNG PARENCHYMA; LUNG RESECTION; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ADOLESCENT; ADULT; AGED; AIRWAY RESISTANCE; ALGORITHMS; DATA INTERPRETATION, STATISTICAL; ELASTICITY; EMPHYSEMA; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LUNG; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MECHANICS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33846565272     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2006.05.009     Document Type: Article

References (28)

1. Barnas G.M., Delaney P.A., Gheorghiu I., Mandava S., Russell R.G., Kahn R., and Mackenzie C.F. Respiratory impedances and acinar gas transfer in a canine model for emphysema. J. Appl. Physiol. 83 1 (1997) 179-188
2. Barnas G.M., Gilbert T.B., Sonett J.R., McGinley M.J., Premuzic M., and Krasna M.J. Effects of lung volume reduction surgery on lung and chest wall impedances. Am. J. Respir. Crit. Care Med. 155 (1997) A605
3. Brantigan O.C., and Mueller E. Surgical Treatment of Pulmonary Emphysema. Am. Surg. 23 (1957) 789-804
4. Colebatch H.J., Finucane K.E., and Smith M.M. Pulmonary conductance and elastic recoil relationships in asthma and emphysema. J. Appl. Physiol. 34 2 (1973) 143-153
5. Ding D.J., Martin J.G., and Macklem P.T. Effects of lung volume on maximal methacholine-induced bronchoconstriction in normal humans. J. Appl. Physiol. 62 3 (1987) 1324-1330
6. Drazen J.M. Surgery for Emphysema-not for Everyone. N. Engl. J. Med. 345 (2001) 1126-1127
7. Fessler H.E., and Permutt S. Lung volume reduction surgery and airflow limitation. Am. J. Respir. Crit. Care Med. 157 (1998) 715-722
8. Gillis H.L., and Lutchen K.R. Airway remodeling in asthma amplifies heterogeneities in smooth muscle shortening causing hyperresponsiveness. J. Appl. Physiol. 86 6 (1999) 2001-2012
9. Goddard P.R., Nicholson E.M., Laszlo G., and Watt I. Computed tomography in pulmonary emphysema. Clin. Radiol. 33 (1982) 379-387
10. Hunsaker A.R., Ingenito E.P., Reilly J.J., and Costello P. Lung volume reduction surgery for emphysema: correlation of ct and v/q imaging with physiologic mechanisms of improvement in lung function. Radiology 222 2 (2002) 491-498
11. Ingenito E.P., Davison B., and Fredberg J.J. Tissue resistance in the guinea pig at baseline and during methacholine constriction. J. Appl. Physiol. 75 6 (1993) 2541-2548
12. Kaczka D.W., Ingenito E.P., Suki B., and Lutchen K.R. Partitioning airway and lung tissue resistances in humans: effects of bronchoconstriction. J. Appl. Physiol. 82 5 (1997) 1531-1541
13. Kaczka D.W., Ingenito E.P., Israel E., and Lutchen K.R. Airway and lung tissue mechanics in asthma: effects of albuterol. Am. J. Respir. Crit. Care Med. 159 (1999) 169-178
14. Kaczka D.W., Ingenito E.P., Body S.C., Duffy S.E., Mentzner S.J., DeCamp M.M., and Lutchen K.R. Inspiratory lung impedance in COPD: effects of PEEP and immediate impact of lung volume reduction surgery. J. Appl. Physiol. 90 (2001) 1833-1841
15. Kohlhaufl M., Brand P., Rock C., Radons T., Scheuch G., Meyer T., Schulz H., Pfeifer K.J., Haussinger K., and Heyeder J. Noninvasive diagnosis of emphysema. Am. J. Respir. Crit. Care Med. 160 (1999) 913-918
16. Lapperre T.S., Snoeck-Stroband J.B., Gosman M.M., Stolk J., Sont J.K., Jansen D.F., Kerstjens H.A., Postma D.S., and Sterk P.J. Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 170 (2004) 499-504
17. Lutchen K.R., Jensen A., Atileh H., Kaczka D.W., Israel E., Suki B., and Ingenito E.P. Airway constriction pattern is a central component of asthma severity: the role of deep inspirations. Am. J. Respir. Crit. Care Med. 164 (2001) 207-215
18. Madani A., Keyzer C., and Gevenois P.A. Quantitative computed tomography assessment of lung structure and function in pulmonary emphysema. Eur. Respir. J. 18 (2001) 720-730
19. Manal K., and Rose W. A general solution for the time delay introduced by a low-pass Butterworth digital filter: an application to musculoskeletal modeling. J. Biomech. 40 (2007) 678-681
20. National Emphysema Treatment Trial Research Group. Patients at high risk of death after lung-volume-reduction surgery. N. Engl. J. Med. 345 (2001) 1075-1083
21. National Emphysema Treatment Trial Research Group. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N. Engl. J. Med. 348 (2003) 2059-2073
22. Otis A.B., McKerrow C.B., Bartlett R.A., Mead J., McIlroy M.B., Selverstone N.J., and Radford Jr. E.P. Mechanical factors in distribution of pulmonary ventilation. J. Appl. Physiol. 8 4 (1956) 427-443
23. Parr D.G., Stoel B.C., Stolk J., and Stockley R.A. Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment. Am. J. Respir. Crit. Care Med. 170 (2004) 1172-1178
24. Robinson T.E., Leung A.N., Northway W.H., Blankenberg F.G., Chan F.P., Bloch D.A., Holmes T.H., and Moss R.B. Composite spirometric-computed tomography outcome measure in early cystic fibrosis lung disease. Am. J. Respir. Crit. Care Med. 168 (2003) 588-593
25. Salazar E., and Knowles J.H. An analysis of pressure-volume characteristics of the lungs. J. Appl. Physiol. 19 1 (1964) 97-104
26. Tepper R.S., Sato J., Suki B., Martin G., and Bates J.H.T. Low-frequency pulmonary impedance in rabbits and its response to inhaled methacholine. J. Appl. Physiol. 73 1 (1992) 290-295
27. Tgavalekos N.T., Venegas J.G., Suki B., and Lutchen K.R. Relation between structure, function, and imaging in a three-dimensional model of the lung. Ann. Biomed. Eng. 31 (2003) 363-373
28. Thurlbeck W.M., and Muller N.L. Emphysema: definition, imaging, and quantification. Am. J. Roentgenol. 163 (1994) 1017-1025