High dietary sucrose triggers hyperinsulinemia, increases myocardial β-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery

Molecular and Cellular Biochemistry

Volumn 295, Issue 1-2, 2007, Pages 217-228

  Gonsolin, D ^a   Couturier, K ^a   Garait, B ^a   Rondel, S ^a   Novel Chate V ^a   Peltier, S ^a   Faure, P ^b   Gachon, P ^c   Boirie, Y ^c   Keriel, C ^a   Favier, R ^a   Pepe, S ^d   Demaison, Luc ^a   Leverve, X ^a  

^a INSERM   (France)

^b HÔPITAL MICHALLON   (France)

^c CRNH AUVERGNE   (France)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Cardiac metabolism; Heart; Ischemia; Metabolic syndrome; Sucrose feeding

Indexed keywords

CARBON 13; FATTY ACID; GLUCOSE; HEXANOIC ACID; INSULIN; LACTIC ACID; OXYGEN; PYRUVIC ACID; STARCH; SUCROSE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW VELOCITY; BODY WEIGHT; CARDIOVASCULAR DISEASE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DIET RESTRICTION; DIETARY INTAKE; DISEASE ASSOCIATION; FATTY ACID OXIDATION; FOOD COMPOSITION; GLYCOLYSIS; HEART CONTRACTION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART WEIGHT; HYPERINSULINEMIA; INSULIN RESISTANCE; ISOLATED HEART; MALE; MASS SPECTROMETRY; MYOCARDIAL DISEASE; NONHUMAN; OXYGEN CONSUMPTION; RAT; SUGAR INTAKE;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIETARY SUCROSE; GLYCOLYSIS; HYPERINSULINISM; INSULIN; LACTIC ACID; LIPIDS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; ORGAN SIZE; OXIDATION-REDUCTION; PYRUVIC ACID; RATS; RATS, WISTAR; TRIGLYCERIDES;

RATTUS; RATTUS NORVEGICUS;

EID: 33846554859     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9291-7     Document Type: Article

References (56)

1. Basciano H, Federico L, Adeli K (2005) Fructose, insulin resistance, and metabolic dyslipidemia Nutr Metab (Lond) 2: 5, 2005
2. Mcauley KA, Hopkins CM, Smith KJ, Mclay RT, Williams SM, Taylor RW, Mann JL (2005) Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women Diabetologia 48: 8-16
3. Winitz M, Graff J, Seedman DA (1964) Effect of dietary carbohydrate on serum cholesterol levels Arch Biochem Biophys 108: 576-579
4. Winitz M, Seedman DA, Graff J (1970) Studies in metabolic nutrition employing chemically defined diets. I. Extended feeding of normal human adult males Am J Clin Nutr 23: 525-545
5. Zavaroni I, Chen YD, Reaven GM (1982) Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat Metabolism 31: 1077-1083
6. Guo X, Cheng S, Taylor KD, Cui J, Hughes R, Quinones MJ, Bulnes-Enriquez I, De la Rosa R, Aurea G, Yang H, Hsueh W, Rotter JI (2005) Hypertension genes are genetic markers for insulin sensitivity and resistance Hypertension 45: 799-803
7. Xi S, Yin W, Wang Z, Kusunoki M, Lian X, Koike T, Fan J, Zhang Q (2004) A minipig model of high-fat/high-sucrose diet-induced diabetes and atherosclerosis Int J Exp Pathol 85: 223-231
8. Streja D (2004) Metabolic syndrome and other factors associated with increased risk of diabetes Clin Cornerstone 6: S14-S29
9. Lempiainen P, Mykkanen L, Pyorala K, Laakso M, Kuusisto J (1999) Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men Circulation 100: 123-128
10. Mangrum A, Bakris GL (1997) Predictors of renal and cardiovascular mortality in patients with non-insulin-dependent diabetes: A brief overview of microalbuminuria and insulin resistance J Diabetes Compl 11: 352-357
11. Scheepers A, Joost HG, Schurmann A (2004) The glucose transporter families SGLT and GLUT: Molecular basis of normal and aberrant function J Parenter Enteral Nutr 28: 364-371
12. Morel S, Berthonneche C, Tanguy S, Toufektsian MC, Foulon T, De Lorgeril M, de Leiris J, Boucher F (2003) Insulin resistance modifies plasma fatty acid distribution and decreases cardiac tolerance to in vivo ischaemia/reperfusion in rats Clin Exp Pharmacol Physiol 30: 446-451
13. Gutman RA, Basilico MZ, Bernal CA, Chicco A, Lombardo YB (1987) Long-term hypertriglyceridemia and glucose intolerance in rats fed chronically an isocaloric sucrose-rich diet Metabolism 36: 1013-1020
14. Segal S, Lloyd S, Sherman N, Sussman K, Draznin B (1990) Postprandial changes in cytosolic free calcium and glucose uptake in adipocytes in obesity and non-insulin-dependent diabetes mellitus Horm Res 34: 39-44
15. (2+) in high-fat-fed rats Metabolism 51: 912-918
16. (2+) chelator on insulin resistance and hypertension in high-fat-fed rats and spontaneously hypertensive rats Metabolism 53: 269-272
17. Benzi RH, Lerch R (1992) Dissociation between contractile function and oxidative metabolism in postischemic myocardium. Attenuation by ruthenium red administred during reperfusion Circ Res 71: 567-576
18. Du Toit E, Opie L (1992) Modulation of severity of reperfusion stunning in the isolated rat heart by agents altering calcium flux at onset of reperfusion Circ Res 70: 960-967
19. Desrois M, Sidell RJ, Gauguier D, Davey CL, Radda GK, Clarke K (2004) Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart J Mol Cell Cardiol 37: 547-555
20. Jordan JE, Simandle SA, Tulbert CD, Busija DW, Miller AW (2003) Fructose-fed rats are protected against ischemia/reperfusion injury J Pharmacol Exp Ther 307: 1007-1011
21. Kristiansen SB, Lofgren B, Stottrup NB, Khatir D, Nielsen-Kudsk JE, Nielsen TT, Botker HE, Flyvbjerg A (2004) Ischaemic preconditioning does not protect the heart in obese and lean animal models of type 2 diabetes Diabetologia 47: 1716-1721
22. Sidell RJ, Cole MA, Draper NJ, Desrois M, Buckingham RE, Clarke K (2002) Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the Zucker fatty rat heart Diabetes 51: 1110-1117
23. Wang P, Chatham JC (2004) Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart Am J Physiol 286: E725-E736
24. Longnus SL, Wambolt RB, Barr RL, Lopaschuk GD, Allard MF (2001) Regulation of myocardial fatty acid oxidation by substrate supply Am J Physiol 281: H1561-H1567
25. 2 isotopic measurement in whole blood: Comparison with expired gas Am J Physiol 276: E212-E216
26. Bergmeyer HU: In: HU Bergmeyer (ed), Methods of enzymatic analysis, Vol. 3. New York, Verlag Chemie Weiheim, 1974
27. Francis GA, Anicotte JS, Auwerx J (2003) PPAR-a effects on the heart and other vascular tissues Am J Physiol 285: H1-H9
28. Poizat C, Grably S, Cuchet P, Keriel C (1996) Relationship between heart function and energy production. A study on isolated rat heart. Arch Physiol Biochem 104: 71-80
29. Dowell RT, Atkins FL, Love S (1986) Integrative nature and time course of cardiovascular alterations in the diabetic rat J Cardiovasc Pharmacol 8: 406-413
30. Hicks KK, Seifen E, Stimers JR, Kennedy RH (1998) Effects of streptozotocin-induced diabetes on heart rate, blood pressure and cardiac autonomic nervous control J Auton Nerv Syst 69: 21-30
31. (+)-ATPase activity in skeletal muscle by epinephrine or amylin Am J Physiol 277: E176-E186
32. Maeda CY, Fernandes TG, Timm HB, Irigoyen MC (1995) Autonomic dysfunction in short-term experimental diabetes Hypertension 26: 1100-1104
33. Oliveira VL, Moreira ED, Farah VD, Consolim-Colombo F, Krieger EM, Irigoyen MC (1999) Cardiopulmonary reflex impairment in experimental diabetes in rats Hypertension 34: 813-817
34. Patel KP, Zhang PL (1995) Baroreflex function in streptozotocin (STZ) induced diabetic rats Diabetes Res Clin Pract 27: 1-9
35. Ramanadham S, Tenner TE (1986) Chronic effects of streptozotocin diabetes on myocardial sensitivity in the rat Diabetologia 29: 741-748
36. Saiki C, Seki N, Furuya H, Matsumoto S (2005) The acute effects of insulin on the cardiorespiratory responses to hypoxia in streptozotocin-induced diabetic rats Acta Physiol Scand 183: 107-115
37. Schaan BD, Dall'ago P, Maeda CY, Ferlin E, Fernandes TG, Schmid H, Irigoyen MC (2004) Relationship between cardiovascular dysfunction and hyperglycemia in streptozotocin-induced diabetes in rats Braz J Med Biol Res 37: 1895-1902
38. +-ATPase activity as a cause of increased lactate production after hemorrhagic shock J Trauma 44: 796-801
39. (+)-ATPase activity during hemorrhage J Surg Res 99: 235-244
40. +-ATPase in insulin-induced lactate release by skeletal muscle Am J Physiol 280: E296-E300
41. Paul RJ, Bauer M, Pease W (1979) Vascular smooth muscle: Aerobic glycolysis linked to sodium and potassium transport processes Science 206: 1414-1416
42. Pierce GN, Philipson KD (1985) Binding of glycolytic enzymes to cardiac sarcolemmal and sarcoplasmic reticular membranes J Biol Chem 260: 6862-6870
43. Weiss J, Hiltbrand B (1985) Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart J Clin Invest 75: 436-447
44. + channels. Evidence for preferential regulation by glycolysis J Gen Physiol 94: 911-935
45. 2+ transport Circ Res 77: 88-97
46. Babick AP, Cantor EJ, Babick JT, Takeda N, Dhalla NS, Netticadan T (2004) Cardiac contractile dysfunction in j2n-k cardiomyopathic hamsters is associated with impaired SR function and regulation Am J Physiol 287: C1202-C1208
47. Narayanan N, Yang C, Xu A (2004) Dexamethasone treatment improves sarcoplasmic reticulum function and contractile performance in aged myocardium Mol Cell Biochem 266: 31-36
48. Suarez J, Gloss B, Belke DD, Hu Y, Scott B, Dieterle T, Kim YK, Valencik ML, McDonald JA, Dillmann WH (2004) Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy Am J Physiol 287: H2164-H2172
49. Rupp H, Maisch B: Radiotelemetric characterization of overweight-associated rises in blood pressure and heart rate. Am J Physiol 277:H1540-H1545, 1999
50. Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP, Delerive P, Fadel A, Chinetti G, Fruchart JC, Najib J, Maclouf J, Tedgui A (1998) Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not PPARgamma activators Nature 393: 790-793
51. Fujino T, Ishii Y, Takeuchi T, Hirasawa K, Tateda K, Kikuchi K, Hasebe N (2003) Recovery of BMIPP uptake and regional wall motion in insulin resistant patients following angioplasty for acute myocardial infarction Circ J 67: 757-762
52. Lopaschuk GD (1997) Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia Am J Cardiol 80: 11A-16A
53. Burkhoff D, Weiss RG, Schulman SP, Kalil-Filho R, Wannenburg T, Gerstenblith G (1991) Influence of metabolic substrate on rat heart function and metabolism at different coronary flow Am J Physiol 261: H741-H750
54. Dyck JR, Cheng JF, Stanley WC, Barr R, Chandler MP, Brown S, Wallace D, Arrhenius T, Harmon C, Yang G, Nadzan AM, Lopaschuk GD (2004) Malonyl coenzyme A decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation Circ Res 94: E78-E84
55. Robergs RA (2001) Exercise-induced metabolic acidosis: Where do the protons come from? Sports Sci 5: 1-20
56. Sentex E, Laurent A, Martine L, Grégoire S, Rochette L, Demaison L (1999) Calcium- and ADP-magnesium-induced uncoupling in isolated cardiac mitochondria: Influence of cyclosporine A Mol Cell Biochem 202: 73-84