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Volumn , Issue 20, 2006, Pages 3447-3450

InCl3-catalyzed alkylation of aromatic and heteroaromatic compounds with cyclic allylic acetates

Author keywords

Alkylation; Aromatics; Cyclic allylic acetates; Indium(III) compounds

Indexed keywords

2 CYCLOHEXENYL FURAN DERIVATIVE; 2 CYCLOHEXENYL PYRROLE DERIVATIVE; 3 (4 CARBETHOXY 3 METHYL 2 CYCLOHEXENYL) 1H INDOLE; 3 CYCLOHEXENYL INDOLE DERIVATIVE; ACETIC ACID DERIVATIVE; AROMATIC COMPOUND; FURAN DERIVATIVE; INDIUM CHLORIDE; INDOLE DERIVATIVE; LEWIS ACID; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 33846534769     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-958418     Document Type: Article
Times cited : (8)

References (18)
  • 18
    • 33846524239 scopus 로고    scopus 로고
    • General Procedure: A mixture of cyclic allylic acetate (1 mmol, arene or indole (2 mmol) and/or pyrrole or furan (4 mmol) and InCl3 (10 mol, in 1,2-dichloroethane (10 mL) was stirred at reflux temperature for the time required to complete the reaction (Table 1, After complete conversion as indicated by TLC, the reaction mixture was diluted with water and extracted with EtOAc (2 × 10 mL, The combined organic layers were dried over anhyd Na2SO4, concentrated in vacuo and purified by column chromatography on silica gel (Merck, 100-200 mesh, EtOAc-hexane, 1:9) to afford the corresponding cyclohexenyl-substituted aromatic or heteroaromatic compound in pure form. Spectral Data for Selected Products: Entry a: 1H NMR (200 MHz, CDCl3, δ, 7.80 (br s, 1 H, NH, 7.65 (d, J, 8.0 Hz, 1 H, 6.85-7.40 (m, 4 H, 5.60 (br s, 1 H, 3.65 (br s, 1 H, 2.05 (m, 4 H, 1.75 (s, 3 H, 1.65 (m, 2 H, IR KBr
    • 3: 262.1569; found: 262.1565.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.