Treatment of restless legs syndrome

Revista Brasileira de Psiquiatria

Volumn 28, Issue 4, 2006, Pages 308-315

  Spolador, Tiago ^a,b   Allis, Johanna Clair Sá ^a   Pondé, Milena Pereira ^a  

^a ESCOLA BAHIANA DE MEDICINA E SAÚDE PÚBLICA   (Brazil)

^b NONE   (Brazil)

Author keywords

Literature review; Parasomnias; Restless legs syndrome; Sleep disorders; Treatment

Indexed keywords

AMANTADINE; APOMORPHINE; BENSERAZIDE; BENZODIAZEPIN 2 ONE DERIVATIVE; CABERGOLINE; CARBIDOPA; CLONAZEPAM; CODEINE; DEXTROPROPOXYPHENE; DIHYDROERGOCRYPTINE; DOMPERIDONE; DOPAMINE RECEPTOR STIMULATING AGENT; ENTACAPONE; GABAPENTIN; IRON; KETAMINE; LEVODOPA; METHADONE; MORPHINE; OPIATE; OXYCODONE; PERGOLIDE; PIRIBEDIL; PLACEBO; PRAMIPEXOLE; ROPINIROLE; TILIDINE; TRAMADOL; UNINDEXED DRUG; ZOLPIDEM;

ABDOMINAL PAIN; ABNORMAL VISION; ALLERGIC REACTION; ANGINA PECTORIS; ANXIETY; APPETITE DISORDER; CARDIAC PAIN; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; DATA BASE; DIARRHEA; DIZZINESS; DREAM; DROWSINESS; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG WITHDRAWAL; DYSPEPSIA; EPIGASTRIC PAIN; FATIGUE; HANGOVER; HEADACHE; HEART ARRHYTHMIA; HEART PALPITATION; HUMAN; INFLAMMATORY DISEASE; INSOMNIA; IRON DEFICIENCY ANEMIA; LEG EDEMA; LETHARGY; MEDICAL LITERATURE; MENTAL CLOUDING; MENTAL DISEASE; MICTURITION; MIGRAINE; MONOTHERAPY; MUSCLE WEAKNESS; MYOSITIS; NAUSEA; NERVOUSNESS; NIGHTMARE; NOCTURIA; PAIN; PANICULITIS; PARESTHESIA; RANDOMIZED CONTROLLED TRIAL; RASH; RESTLESS LEGS SYNDROME; REVIEW; RHINITIS; SIDE EFFECT; SKIN PRURITUS; SOMNOLENCE; STOMACH PAIN; SUBCUTANEOUS NODULE; TACHYCARDIA; THORAX PAIN; TREMOR; VERTIGO; VOMITING; WEIGHT REDUCTION; XEROSTOMIA;

AMINES; ANALGESICS, OPIOID; ANTICONVULSANTS; CYCLOHEXANECARBOXYLIC ACIDS; DOPAMINE AGENTS; DOUBLE-BLIND METHOD; GAMMA-AMINOBUTYRIC ACID; HUMANS; LEVODOPA; RANDOMIZED CONTROLLED TRIALS; RESTLESS LEGS SYNDROME;

EID: 33846487212     PISSN: 15164446     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1516-44462006000400012     Document Type: Review

References (48)

1. Weimerskirch PR, Ernst ME. Newer dopamine agonists in the treatment of restless legs syndrome. Ann Pharmacother. 2001;35(5):627-30.
2. Chaudhuri KR, Appiah-Kubi LS, Trenkwalder C. Restless legs syndrome. J Neurol Neurosurg Psychiatry. 2001;71(2):143-6.
3. Tan EK, Ondo W. Restless legs syndrome: clinical features and treatment. Am J Med Sci. 2000;319(6):397-403.
4. Reimão R. Sono: estudo abrangente. 2a ed. São Paulo: Atheneu; 1996. p. 273-7.
5. Philips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Intern Med. 2000;160(14):2137-41.
6. Tan EK, Seah A, See SJ, Lim E, Wong MC, Koh KK. Restless legs syndrome in an Asian population: a study in Singapore. Mov Disord. 2001;16(3):577-9.
7. Rothdach A, Trenkwalder C, Haberstock J, Keil U, Berger K. Prevalence and risk factors of RLS in an elderly population: the MEMO study. Memory and Morbidity in Augsburg Elderly. Neurology. 2000;54:1064-8.
8. Lee KA, Zaffke ME, Baratee-Beebe K. Restless legs syndrome and sleep disturbance during pregnancy: the role of folate and iron. J Womens Health Gen Based Med. 2001;10(4):335-41.
9. Janzen L, Rich JA, Vercaigne LM. An overview of levodopa in the management of restless legs syndrome in a dialysis population: pharmacokinetics, clinical trials, and complications of therapy. Ann Pharmacother. 1999;33(1):86-92.
10. Trenkwalder C, Seidel VC, Gasser T, Oertel WH. Clinical symptoms and possible anticipation in a large kindred of familial restless legs syndrome. Mov Disord. 1996;11(4):389-94.
11. Walther BW. Treating restless legs syndrome: current pathophysiological concepts and clinical trials. Expert Opin Investig Drugs. 2002;11(4):501-14.
12. Allen RP, Earley CJ. Restless legs syndrome: a review of clinical and pathophysiologic features. J Clin Neurophysiol. 2001;18(2):128-47.
13. Clark MM. Restless legs syndrome. J Am Board Fam Pract. 2001;14(5):368-74.
14. Reimão R. Síndrome das pernas inquietas: atualização terapêutica. Rev Bras Neurol Psiquiatr. 1998;2(3):95-8.
15. Hening W, Allen R, Earley C, Picchietti D, Silber M. The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine review. Sleep. 1999;22(7):970-99.
16. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep. 1996;19(3):205-13.
17. Montplaisir J, Godbout R, Poirier G, Bedard MA. Restless legs syndrome and periodic movements in sleep: physiopathology and treatment with L-dopa. Clin Neuropharmacol. 1986;9(5):456-63.
18. Guilleminault C, Cetel M, Philip P. Dopaminergic treatment of restless legs and rebound phenomenon. Neurology. 1993;43(2):445.
19. Evidente VG, Adler CH, Caviness JN, Hentz JG, Gwinn-Hardy K. Amantadine is beneficial in restless legs syndrome. Mov Disord. 2000;15(2):324-7.
20. Benes H, Kurella B, Kummer J, Kazenwadel J, Selzer R, Kohnen R. Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial. Sleep. 1999;22(8):1073-81.
21. Saletu M, Anderer P, Hogl B, Saletu-Zyhlarz G, Kunz A, Poewe W, Saletu B. Acute double-blind, placebo-controlled sleep laboratory and clinical follow-up studies with a combination treatment of rr-L-dopa and sr-L-dopa in restless legs syndrome. J Neural Transm. 2003;110(6):611-26.
22. Collado-Seidel V, Kazenwadel J, Wetter TC, Kohnen R, Winkelmann J, Selzer R, Oertel WH, Trenkwalder C. A controlled study of additional sr-L-dopa in L-dopa-responsive restless legs syndrome with late-night symptoms. Neurology. 1999;52(2):285-90.
23. Wetter TC, Stiasny K, Winkelmann J, Buhlinger A, Brandenburg U, Penzel T, Medori R, Rubin M, Oertel WH, Trenkwalder C. A randomized controlled study of pergolide in patients with restless legs syndrome. Neurology. 1999;52(5):944-50.
24. Stiasny K, Wetter TC, Winkelmann J, Brandenburg U, Penzel T, Rubin M, Hundemer HP, Oertel WH, Trenkwalder C. Long-term effects of pergolide in the treatment of restless legs syndrome. Neurology. 2001;56(10):1399-402.
25. Walters AS, Mandelbaum DE, Lewin DS, Kugler S, England SJ, Miller M. Dopaminergic therapy in children with restless legs/periodic limb movements in sleep and ADHD. Dopaminergic Therapy Study Group. Pediatr Neurol. 2000;22(3):182-6.
26. Montplaisir J, Nicolas A, Denesle R, Gomez-Mancilla B. Restless legs syndrome improved by pramipexole: a double-blind randomized trial. Neurology. 1999;52(5):938-43.
27. Montplaisir J, Denesle R, Petit D. Pramipexole in the treatment of restless legs syndrome: a follow-up study. Eur J Neurol. 2000;7(Suppl 1):27-31.
28. Saletu M, Anderer P, Saletu-Zyhlarz G, Hauer C, Saletu B. Acute placebo-controlled sleep laboratory studies and clinical follow-up with pramipexole in restless legs syndrome. Eur Arch Psychiatry Clin Neurosci. 2002;252(4):185-94.
29. Saletu B, Gruber G, Saletu M, Brandstatter N, Hauer C, Prause W, Ritter K, Saletu-Zyhlarz G. Sleep laboratory studies in restless legs syndrome patients as compared with normal and acute effects of ropinirole. 1. Findings on objective and subjective sleep and awakening quality. Neuropsychobiology. 2000;41(4):181-9.
30. Saletu M, Anderer P, Saletu B, Hauer C, Mandl M, Oberndorfer S, Zoghlami A, Saletu-Zyhlarz G. Sleep laboratory studies in restless legs syndrome patients as compared with normal and acute effects of ropinirole. 2. Findings on periodic leg movements, arousals and respiratory variables. Neuropsychobiology. 2000;41(4):190-9.
31. Ondo W. Ropinirole for restless legs syndrome. Mov Disord. 1999;14(1):890-2.
32. Stiasny K, Röbbecke J, Schuler P, Oertel WH. Treatment of idiopathic restless legs syndrome (RLS) with the D2-agonist cabergoline - an open clinical trial. Sleep. 2000;23(3):349-54.
33. Stiasny K. Clinical data on restless legs syndrome: a dose-finding study with cabergoline. Eur Neurol. 2001;46(Suppl 1):24-6.
34. Tergau F, Wischer S, Wolf C, Paulus W. Treatment of restless legs syndrome with the dopamine agonist alpha-dihydroergocryptine. Mov Disord. 2001;16(4):731-5.
35. Evidente VG. Piribedil for restless legs syndrome: a pilot study. Mov Disord. 2001;16(3):579-81.
36. Garcia-Borreguero D, Larrosa O, de la Llave Y, Verger K, Masramon X, Hernandez G. Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study. Neurology. 2002;59(10):1573-9.
37. Thorp ML, Morris CD, Bagby SP. A crossover study of gabapentin in treatment of restless legs syndrome among hemodialysis patients. Am J Kidney Dis. 2001;38(1):104-8.
38. Happe S, Klösch G, Saletu B, Zeitlhofer J. Treatment of idiopathic restless legs syndrome (RLS) with gabapentin. Neurology. 2001;57(9):1717-9.
39. Davis BJ, Rajput A, Rajput ML, Aul EA, Eichhorn GR. A randomized, double-blind placebo-controlled trial of iron in restless legs syndrome. Eur Neurol. 2000;43(2):70-5.
40. Barton JC, Wooten VD, Acton RT. Hemochromatosis and iron therapy of restless legs syndrome. Sleep Med. 2001;2(3):249-51.
41. Walters AS, Winkelmann J, Trenkwalder C, Fry JM, Kataria V, Wagner M, Sharma R, Hening W, Li L. Long-term follow-up on restless legs syndrome patients treated with opioids. Mov Disord. 2001;16(6):1105-9.
42. Lauerma H, Markkula J. Treatment of restless legs syndrome with tramadol: an open study. J Clin Psychiatr. 1999;60(4):241-4.
43. Reuter I, Ellis CM, Ray Chaudhuri K. Nocturnal subcutaneous apomorphine infusion in Parkinson's disease and restless legs syndrome. Acta Neurol Scand. 1999;100(3):163-7.
44. Jakobsson B, Ruuth K. Successful treatment of restless legs syndrome with an implanted pump for intrathecal drug delivery. Acta Anaesthesiol Scand. 2002;46(1):114-7.
45. Saletu M, Anderer P, Saletu-Zyhlarz G, Prause W, Semler B, Zoghlami A, Gruber G, Hauer C, Saletu B. Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD): acute placebo-controlled sleep laboratory studies with clonazepam. Eur Neuropsychopharmacol. 2001;11(2):153-61.
46. Bezerra ML, Martínez JV. Zolpidem in restless legs syndrome. Eurol Neurol. 2002;48(3):180-1.
47. Sharif AA. Entacapone in restless legs syndrome. Mov Disord. 2002;17(2):421.
48. Kapur N, Friedman R. Oral ketamine: a promising treatment for restless legs syndrome. Anesth Analg. 2002;94(6):1558-9, table of contents.