Vancomycin bound to Ti rods reduces periprosthetic infection: Preliminary study

Clinical Orthopaedics and Related Research

Volumn 461, Issue , 2007, Pages 88-95

  Antoci Jr , Valentin ^a   Adams, Christopher S ^a   Hickok, Noreen J ^a   Shapiro, Irving M ^a   Parvizi, Javad ^b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c ROTHMAN INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TITANIUM; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; BACTERIUM ADHERENCE; BIOFILM; BONE INFECTION; COLONY FORMING UNIT; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CONTROLLED STUDY; FEMUR; IMPLANT; NONHUMAN; PRIORITY JOURNAL; PROSTHESIS INFECTION; RAT; STAPHYLOCOCCUS AUREUS; X RAY FILM; ANIMAL; ARTICLE; CELL PROLIFERATION; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; INFECTION; MICROBIOLOGY; PROSTHESES AND ORTHOSES; WISTAR RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; PROSTHESES AND IMPLANTS; PROSTHESIS-RELATED INFECTIONS; RATS; RATS, WISTAR; TITANIUM; VANCOMYCIN;

EID: 33846474130     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/BLO.0b013e318073c2b2     Document Type: Conference Paper

References (23)

1. Bratzler DW, Houck PM. Surgical Infection Prevention Guideline Writers Workgroup. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Am J Surg. 2005;189:395-404.
2. Buttaro M, Valentini R, Piccaluga F. Persistent infection associated with residual cement after resection arthroplasty of the hip. Acta Orthop Scand. 2004;75:427-429.
3. Cierny G 3rd, DiPasquale D. Periprosthetic total joint infections: staging, treatment, and outcomes. Clin Orthop Relat Res. 2002;403:23-28.
4. Dyce J, Olmstead ML. Removal of infected canine cemented total hip prostheses using a femoral window technique. Vet Surg. 2002;31:552-560.
5. Geipel U, Herrmann M. The infected implant. Part 1: bacteriology. [in German]. Orthopade. 2004;33:1411-1428.
6. Gosden PE, MacGowan AP, Bannister GC. Importance of air quality and related factors in the prevention of infection in orthopaedic implant surgery. J Hosp Infect. 1998;39:173-180.
7. Hanssen AD, Spangehl MJ. Practical applications of antibiotic-loaded bone cement for treatment of infected joint replacements. Clin Orthop Relat Res. 2004;427:79-85.
8. Henry GD, Wilson SK, Delk JR, Carson CC, Wiygul J, Tornehl C, Cleves MA, Silverstein A, Donatucci CF. Revision washout decreases penile prosthesis infection in revision surgery: a multicenter study. J Urol. 2005;173:89-92.
9. Hopkins CC. Recognition of endemic and epidemic prosthetic device infections: the role of surveillance, the hospital infection control practitioner, and the hospital epidemiologist. Infect Dis Clin North Am. 1989;3:211-220.
10. Jose B, Antoci V Jr, Zeiger AR, Wickstrom E, Hickok NJ. Vancomycin covalently bonded to titanium beads kills Staphylococcus aureus. Chem Biol. 2005;12:1041-1048.
11. Kalteis T, Luring C, Gugler G, Zysk S, Caro W, Handel M, Grifka J. Acute tissue toxicity of PMMA bone cements [in German]. Z Orthop Ihre Grenzgeb. 2004;142:666-672.
12. Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Haas NP, Raschke M. Gentamicin coating of metallic implants reduces implant-related osteomyelitis in rats. Bone. 2003;32:521-531.
13. Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Stemberg A, Haas NP, Raschke M. A new model of implant-related osteomyelitis in rats. J Biomed Mater Res B Appl Biomater. 2003;67:593-602.
14. McLaren AC, McLaren SG, Nelson CL, Wassell DL, Olsen KM. The effect of sampling method on the elution of tobramycin from calcium sulfate. Clin Orthop Relat Res. 2002;403:54-57.
15. McPherson EJ, Woodson C, Holtom P, Roidis N, Shufelt C, Patzakis MJ. Periprosthetic total hip infection: outcomes using a staging system. Clin Orthop Relat Res. 2002;403:8-15.
16. Nelson CL. The current status of material used for depot delivery of drugs. Clin Orthop Relat Res. 2004;427:72-78.
17. Neut D, van de Belt H, Stokroos I, van Horn JR, van der Mei HC, Busscher HJ. Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery. J Antimicrob Chemother. 2001;47:885-891.
18. Parvizi J, Antoci V Jr, Hickok NJ, Shapiro IM. Selfprotective smart orthopedic implants. Expert Rev Med Devices. 2007;4:55-64.
19. Parvizi J, Wickstrom E, Zeiger AR, Adams CS, Shapiro IM, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH, Hickok NJ. Frank Stinchfield Award. Titanium surface with biologic activity against infection. Clin Orthop Relat Res. 2004;429:33-38.
20. Puolakka TJ, Pajamaki KJ, Halonen PJ, Pulkkinen PO, Paavolainen P, Nevalainen JK. The Finnish Arthroplasty Register: report of the hip register. Acta Orthop Scand. 2001;72:433-441.
21. Trampuz A, Zimmerli W. New strategies for the treatment of infections associated with prosthetic joints. Curr Opin Investig Drugs. 2005;6:185-190.
22. Volin SJ, Hinrichs SH, Garvin KL. Two-stage reimplantation of total joint infections: a comparison of resistant and non-resistant organisms. Clin Orthop Relat Res. 2004;427:94-100.
23. Youngman JR, Ridgway GL, Haddad FS. Antibiotic-loaded cement in revision joint replacement. Hosp Med. 2003;64:613-616.