Pyridoxal 5′-phosphate may be curative in early-onset epileptic encephalopathy

Journal of Inherited Metabolic Disease

Volumn 30, Issue 1, 2007, Pages 96-99

  Hoffmann, G F ^a   Schmitt, B ^b   Windfuhr, M ^c   Wagner, N ^c   Strehl, H ^c   Bagci, S ^d   Franz, A R ^d   Mills, P B ^e   Clayton, P T ^e   Baumgartner, M R ^b   Steinmann, B ^b   Bast, T ^a   Wolf, N I ^a   Zschocke, Johannes ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c Childrens Hospital Dortmund   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 O METHYLDOPA; 5 HYDROXYINDOLEACETIC ACID; ANTICONVULSIVE AGENT; CLONAZEPAM; CORTICOTROPIN; GLYCINE; HISTIDINE; HOMOVANILLIC ACID; PHENOBARBITAL; PHENYTOIN; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAMINE PHOSPHATE OXIDASE; PYRIDOXINE; SERINE; SEROTONIN; TAURINE; THREONINE; VIGABATRIN; VITAMIN B COMPLEX;

ARTICLE; BRAIN ATROPHY; BRAIN DISEASE; CHEMICAL ANALYSIS; CHILDHOOD MORTALITY; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; DRUG DOSE INCREASE; ELECTROENCEPHALOGRAM; ENZYME DEFICIENCY; EPILEPSY; FEMALE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INFANT; INTRACTABLE EPILEPSY; INTRACTABLE PAIN; KETOGENIC DIET; LACTIC ACIDOSIS; MALE; MENTAL DEFICIENCY; MISSENSE MUTATION; MUSCLE SPASM; MUTATIONAL ANALYSIS; MYOCLONUS; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PROTEIN CEREBROSPINAL FLUID LEVEL; PSYCHOMOTOR RETARDATION; SEROTONIN BLOOD LEVEL; TREATMENT RESPONSE; BIOLOGICAL MODEL; INBORN ERROR OF METABOLISM; ONSET AGE; TIME;

AGE OF ONSET; BRAIN DISEASES; CHILD, PRESCHOOL; EPILEPSY; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; METABOLISM, INBORN ERRORS; MODELS, BIOLOGICAL; PYRIDOXAL PHOSPHATE; PYRIDOXAMINEPHOSPHATE OXIDASE; TIME FACTORS; VITAMIN B COMPLEX;

EID: 33846454698     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-006-0508-4     Document Type: Article

References (9)

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2. Clayton PT, Surtees RA, DeVile C, Hyland K, Heales SJ (2003) Neonatal epileptic encephalopathy. Lancet 361: 1614.
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