Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extraction

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 846, Issue 1-2, 2007, Pages 273-280

  Mercolini, Laura ^a   Bugamelli, Francesca ^a   Kenndler, Ernst ^b   Boncompagni, Giancarlo ^c   Franchini, Livia ^d   Raggi, Maria Augusta ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d Azienda USL di Bologna   (Italy)

Author keywords

Clozapine; Human plasma; Levomepromazine; Liquid chromatography; Metabolites; Solid phase extraction

Indexed keywords

CLOZAPINE; HUMAN PLASMA; LEVOMEPROMAZINE; SOLID PHASE EXTRACTION;

ACETONITRILE; BIOASSAY; BODY FLUIDS; COLUMN CHROMATOGRAPHY; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES;

DRUG PRODUCTS;

10,11 DIHYDRO 10,11 DIHYDROXYCARBAMAZEPINE; AMILORIDE; AMISULPRIDE; AMITRIPTYLINE; AMOXAPINE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CARBAMAZEPINE; CARBAMAZEPINE 10,11 OXIDE; CHLORPROMAZINE; CLOZAPINE; CLOZAPINE N OXIDE; DRUG METABOLITE; HALOPERIDOL; IMIPRAMINE; INDOMETACIN; LEVOMEPROMAZINE; LEVOMEPROMAZINE SULFOXIDE; LOXAPINE; MIRTAZAPINE; NEUROLEPTIC AGENT; NORCLOZAPINE; NORLEVOMEPROMAZINE; O DESMETHYLLEVOMEPROMAZINE; PALIPERIDONE; PHOSPHATE; THIORIDAZINE; TRIETHYLAMINE; TRIPROLIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACCURACY; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG MONITORING; DRUG PURIFICATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; POLYPHARMACY; PRIORITY JOURNAL; RELIABILITY; SOLID PHASE EXTRACTION; STANDARD; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

ANTIPSYCHOTIC AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOZAPINE; HUMANS; METHOTRIMEPRAZINE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33846452947     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.09.019     Document Type: Article

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