Characteristic features of in vivo skin microvascular reactivity in CADASIL

Journal of Cerebral Blood Flow and Metabolism

Volumn 27, Issue 2, 2007, Pages 250-257

  Gobron, Claire ^a   Vahedi, Katayoun ^a   Vicaut, Eric ^b   Stucker, Olivier ^b   Laemmel, Elisabeth ^b   Baudry, Nathalie ^b   Bousser, Marie Germaine ^a   Chabriat, Hugues ^a  

^a HÔPITAL LARIBOISIÈRE   (France)

^b Laboratoire d'Etude de la Microcirculation   (France)

Author keywords

Cadasil; Laser doppler; Microcirculation; Skin

Indexed keywords

ACETYLCHOLINE; GLYCERYL TRINITRATE; NITROPRUSSIDE SODIUM; NOTCH3 RECEPTOR;

ADULT; AGED; ARTERY DIAMETER; ARTERY ENDOTHELIUM; ARTERY OCCLUSION; ARTICLE; BLOOD VESSEL REACTIVITY; BRACHIAL ARTERY; CADASIL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HYPEREMIA; IN VIVO STUDY; IONTOPHORESIS; LASER DOPPLER FLOWMETRY; MALE; MICROVASCULATURE; PRIORITY JOURNAL; SKIN BLOOD VESSEL; VASODILATATION;

EID: 33846436081     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600356     Document Type: Article

References (27)

1. Abou-Elenin K, Xydakis A, Hamdy O, Economides PA, Horton ES, Veves A (2002) The effect of aspirin and various iontophoresis solution vehicles on skin microvascular reactivity. Microvasc Res 63:91-5
2. Berghoff M, Kathpal M, Kilo S, Hilz MJ, Freeman R (2002) Vascular and neural mechanisms of ACh-mediated vasodilation in the forearm cutaneous microcirculation. J Appl Physiol 92:780-8
3. Bijlstra PJ, den Arend JA, Lutterman JA, Russel FG, Thien T, Smits P (1996) Blockade of vascular ATP-sensitive potassium channels reduces the vasodilator response to ischaemia in humans. Diabetologia 39:1562-8
4. Bircher A, de Boer EM, Agner T, Wahlberg JE, Serup J (1994) Guidelines for measurement of cutaneous blood flow by laser Doppler flowmetry. A report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 30:65-72
5. Chabriat H, Levy C, Taillia H, Iba-Zizen MT, Vahedi K, Joutel A, Tournier-Lasserve E, Bousser MG (1998) Patterns of MRI lesions in CADASIL. Neurology 51:452-7
6. Chabriat H, Pappata S, Ostergaard L, Clark CA, Pachot-Clouard M, Vahedi K, Jobert A, Le Bihan D, Bousser MG (2000) Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking. Stroke 31:1904-12
7. Chowienczyk PJ, Watts GF, Cockcroft JR, Ritter JM (1992) Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia. Lancet 340:1430-2
8. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, Herrington D, Vallance P, Vita J, Vogel R (2002) Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39:257-65
9. Dakak N, Husain S, Mulcahy D, Andrews NP, Panza JA, Waclawiw M, Schenke W, Quyyumi AA (1998) Contribution of nitric oxide to reactive hyperemia: impact of endothelial dysfunction. Hypertension 32:9-15
10. Dubroca C, Lacombe P, Domenga V, Maciazek J, Levy B, Tournier-Lasserve E, Joutel A, Henrion D (2005) Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy. Stroke 36:113-7
11. Fullerton A, Stucker M, Wilhelm KP, Wardell K, Anderson C, Fischer T, Nilsson GE, Serup J (2002) Guidelines for visualization of cutaneous blood flow by laser Doppler perfusion imaging. A report from the Standardization Group of the European Society of Contact Dermatitis based uponthe HIRELADO European community project. Contact Dermatitis 46:129-40
12. Hussain MB, Singhal S, Markus HS, Singer DR (2004) Abnormal vasoconstrictor responses to angiotensin II and noradrenaline in isolated small arteries from patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Stroke 35:853-8
13. Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C, Luscher TF (1995) Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 91:1314-9
14. Joutel A, Andreux F, Gaulis S, Domenga V, Cecillon M, Battail N, Piga N, Chapon F, Godfrain C, Tournier-Lasserve E (2000) The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients. J Clin Invest 105:597-605
15. Joutel A, Corpechot C, Ducros A, Vahedi K, Chabriat H, Mouton P, Alamowitch S, Domenga V, Cecillion M, Marechal E, Maciazek J, Vayssiere C, Cruaud C, Cabanis EA, Ruchoux MM, Weissenbach J, Bach JF, Bousser MG, Tournier-Lasserve E (1996) Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 383:707-10
16. Joutel A, Favrole P, Labauge P, Chabriat H, Lescoat C, Andreux F, Domenga V, Cecillon M, Vahedi K, Ducros A, Cave-Riant F, Bousser MG, Tournier-Lasserve E (2001) Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis. Lancet 358:2049-51
17. Joutel A, Tournier-Lasserve E (2002) Molecular basis and physiopathogenic mechanisms of CADASIL: a model of small vessel diseases of the brain]. J Soc Biol 196:109-15
18. Joutel A, Vahedi K, Corpechot C, Troesch A, Chabriat H, Vayssiere C, Cruaud C, Maciazek J, Weissenbach J, Bousser MG, Bach JF, Tournier-Lasserve E (1997) Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients. Lancet 350:1511-5
19. Kalimo H, Ruchoux MM, Viitanen M, Kalaria RN (2002) CADASIL: a common form of hereditary arteriopathy causing brain infarcts and dementia. Brain Pathol 12:371-84
20. Monsuez JJ (2001) Mediators of reactive hyperemia. Arch Mal Coeur Vaiss 94:591-9
21. Noon JP, Walker BR, Hand MF, Webb DJ (1998) Studies with iontophoretic administration of drugs to human dermal vessels in vivo: cholinergic vasodilatation is mediated by dilator prostanoids rather than nitric oxide. Br J Clin Pharmacol 45:545-50
22. Pfefferkorn T, von Stuckrad-Barre S, Herzog J, Gasser T, Hamann GF, Dichgans M (2001) Reduced cerebrovascular CO(2) reactivity in CADASIL: a transcranial Doppler sonography study. Stroke 32:17-21
23. Prewitt RL (2002) Autoregulation of blood flow, endothelial nitric oxide synthase and microvascular rarefaction. J Hypertens 20:177-8
24. Ramsay JE, Ferrell WR, Greer IA, Sattar N (2002) Factors critical to iontophoretic assessment of vascular reactivity: implications for clinical studies of endothelial dysfunction. J Cardiovasc Pharmacol 39:9-17
25. Ruchoux MM, Guerouaou D, Vandenhaute B, Pruvo JP, Vermersch P, Leys D (1995) Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Acta Neuropathol (Berl) 89:500-12
26. Taddei S, Virdis A, Ghiadoni L, Sudano I, Notari M, Salvetti A (1999) Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension. Circulation 100:1680-3
27. Vicaut E, Baudry N, Hou X (1994) Nitric oxide-independent response to acetylcholine by terminal arterioles in rat cremaster muscle. J Appl Physiol 77:526-33