Fixed drug eruption induced by an iodinated non-ionic X-ray contrast medium: A practical approach to identify the causative agent and to prevent its recurrence

European Radiology

Volumn 17, Issue 2, 2007, Pages 485-489

  Böhm, Ingrid ^a   Medina, Jesus ^b   Prieto, Pilar ^b   Block, Wolfgang ^a   Schild, Hans H ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Justesa Imagen SA   (Spain)

Author keywords

Adverse reaction; Non ionic contrast medium; Secondary prophylaxis

Indexed keywords

ACETYLSALICYLIC ACID; GADOBUTROL; GADOLINIUM PENTETATE; IMERON 300; IODINATED CONTRAST MEDIUM; IODIXANOL; IOHEXOL; IOMEPROL; IOPAMIDOL; IOPROMIDE; IOTROLAN; MEGLUMINE IOXAGLATE PLUS SODIUM IOXAGLATE; MEPREDNISONE; UNCLASSIFIED DRUG; VISIPAQUE 320;

ADULT; ARTICLE; BURNING SENSATION; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FIXED DRUG ERUPTION; HEAT SENSATION; HUMAN; INGUINAL REGION; MALE; NEOPLASM; PATCH TEST; PRICK TEST; PRIORITY JOURNAL; RECURRENT DISEASE; SECONDARY PREVENTION; SIDE EFFECT; SKIN MANIFESTATION; X RAY;

CONTRAST MEDIA; DRUG ERUPTIONS; HUMANS; INJECTIONS, INTRAVENOUS; IOHEXOL; MALE; MIDDLE AGED; PATCH TESTS; RADIATION, NONIONIZING; RECURRENCE;

EID: 33846433122     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00330-006-0371-6     Document Type: Article

References (25)

1. Christiansen C, Pichler WJ, Skotland T (2000) Delayed allergy-like reactions to X-ray contrast media: Mechanistic considerations. Eur Radiol 10:1965-1975
2. No authors listed G (1996) Delayed allergy-like reactions to X-ray contrast media. Exploration of the problem. Eur Radiol 6 (5 Suppl):1-24
3. Munechika H, Hiramatsu Y, Kudo S, Sugimura K, Hamada C, Yamaguchi K, Katayama H (2003) A prospective survey of delayed adverse reactions to iohexol in urography and computed tomography. Eur Radiol 13:185-194
4. Pedersen SH, Svaland MG, Reiss AL, Andrew E (1998) Late allergy-like reactions following vascular administration of radiography contrast media. Acta Radiol 39:344-348
5. Rydberg J, Charles J, Aspelin P (1998) Frequency of late allergy-like adverse reactions following injection of intravascular non-ionic contrast media. A retrospective study comparing a non-ionic monomeric contrast medium with a non-ionic dimeric contrast medium. Acta Radiol 39:219-222
6. Webb JA, Stacul F, Thomsen HS, Morcos SK (2003) The Contrast Media Safety Committee of the European Society Of Urogenital Radiology. Late adverse reactions to intravascular iodinated contrast media. Eur Radiol 13:181-184
7. Fransson SG, Stenport G, Andersson M (1996) Immediate and late adverse reactions in coronary angiography. A comparison between iodixanol and ioxaglate. Acta Radiol 37:218-222
8. Sutton AG, Finn P, Grech ED, Hall JA, Stewart MJ, Davies A, de Belder MA (2001) Early and late reactions after the use of iopamidol 340, ioxaglate 320, and iodixanol 320 in cardiac catheterization. Am Heart J 141:677-683
9. Hosoya T, Yamaguchi K, Akutsu T, Mitsuhashi Y, Kondo S, Sugai Y, Adachi M (2000) Delayed adverse reactions to iodinated contrast media and their risk factors. Radiat Med 18:39-45
10. Yasuda R, Munechika H (1998) Delayed adverse reactions to nonionic monomeric contrast-enhanced media. Invest Radiol 33:1-5
11. Böhm I, Schild HH (2006) A practical guide to diagnose lesser-known immediate and delayed contrast media-induced adverse cutaneous reactions. Eur Radiol 16:1570-1579
12. Romano A, Artesani MC, Andriolo M, Viola M, Pettinato R, Vecchioli-Scaldazza A (2002) Effective prophylactic protocol in delayed hypersensitivity to contrast media: Report of a case involving lymphocyte transformation studies with different compounds. Radiology 225:466-470
13. Watanabe H, Sueki H, Nakada T, Akiyama M, Iijima M (1999) Multiple fixed drug eruption caused by iomeprol (Iomeron), a nonionic contrast medium. Dermatology 198:291-294
14. Akiyama M, Iijima M, Fujisawa R (1990) Clinical analysis of drug eruption due to iohexol (Omnipaque). Nippon Hifuka Gakkai Zasshi 100:1057-1060
15. Asano S, Ikeda M, Ichikawa E, Okabe S, Kawamura T, Maeda M (1990) Drug eruption due to iohexol (Omnipaque) Rinsho Hoshasen 35:533-536
16. Yamauchi R, Morita A, Tsuji T (1997) Fixed drug eruption caused by iopamidol, a contrast medium. J Dermatol 24:243-245
17. Benson PM, Giblin WJ, Douglas DM (1990) Transient, nonpigmenting fixed drug eruption caused by radiopaque contrast media. J Am Acad Dermatol 23:379-381
18. Good AE, Novak E, Sonda LP 3rd (1980) Fixed eruption and fever after urography. South Med J 73:948-949
19. Alanko K (1994) Topical provocation of fixed drug eruption. A study of 30 patients. Contact Dermatitis 31:25-27
20. Vernassiere C, Trechot P, Commun N, Schmutz JL, Barbaud A (2004) Low negative predictive value of skin tests in investigating delayed reactions to radio-contrast media. Contact Dermatitis 50:359-366
21. Kanzaki T, Sakagami H (1991) Late phase allergic reaction to a CT contrast medium (iotrolan). J Dermatol 18:528-531
22. Zonzits E, Aberer W, Tappeiner G (1992) Drug eruptions from mesna. After cyclophosphamide treatment of patients with systemic lupus erythematosus and dermatomyositis. Arch Dermatol 128:80-82
23. Kanny G, Pichler W, Morisset M, Franck P, Marie B, Kohler C, Renaudin JM, Beaudouin E, Laudy JS, Moneret-Vautrin DA (2005) T cell-mediated reactions to iodinated contrast media: Evaluation by skin and lymphocyte activation tests. J Allergy Clin Immunol 115:179-185
24. Brockow K, Kiehn M, Kleinheinz A, Vieluf D, Ring J (1999) Positive skin tests in late reactions to radiographic contrast media. Allerg Immunol (Paris) 31:49-51
25. Shiohara T, Mizukawa Y, Teraki Y (2002) Pathophysiology of fixed drug eruption: The role of skin-resident T cells. Curr Opin Allergy Clin Immunol 2:317-323