Assessment of Cardiac Function During Axial-flow Left Ventricular Assist Device Support Using a Left Ventricular Pressure-derived Relationship: Comparison With Pre-load Recruitable Stroke Work

Journal of Heart and Lung Transplantation

Volumn 26, Issue 2, 2007, Pages 159-166

  McConnell, Patrick I ^a   Del Rio, Carlos L ^a   Kwiatkowski, Pawel ^a   Farrar, David J ^b   Sun, Benjamin C ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b THORATEC CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSISTED CIRCULATION; BETA ADRENERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; HEART FUNCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE PRESSURE; HEART STROKE VOLUME; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEART VENTRICLE FUNCTION; HEART VOLUME; HEART WORK; LOADING TEST; MANOMETER; NONHUMAN; PRIORITY JOURNAL; SHEEP;

ANIMALS; HEART-ASSIST DEVICES; PRESSURE; SHEEP; STROKE VOLUME; VENTRICULAR FUNCTION, LEFT;

EID: 33846395046     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2006.11.010     Document Type: Article

References (34)

1. Farrar D.J., Holman W.R., McBride L.R., et al. Long-term follow-up of Thoratec ventricular assist device bridge-to-recovery patients successfully removed from support after recovery of ventricular function. J Heart Lung Transplant 21 (2002) 516-521
2. Hetzer R., Mueller J., Weng Y., Wallukat G., Spiegelsberger S., and Loebe M. Cardiac recovery in dilated cardiomyopathy by unloading with a left ventricular assist device. Ann Thorac Surg 68 (1999) 742-749
3. Nakatani T., Sasako Y., Kobayashi J., et al. Long-term circulatory support to promote recovery from profound heart failure. ASAIO J 41 (1995) 526-530
4. Bruckner B.A., Stetson S.J., Perez-Verdia A., et al. Regression of fibrosis and hypertrophy in failing myocardium following mechanical circulatory support. J Heart Lung Transplant 20 (2001) 457-464
5. Levin H., Oz M., Chen J., Packer M., Rose E., and Burkhoff D. Reversal of chronic ventricular dilation in patients with end-stage cardiomyopathy by prolonged mechanical unloading. Circulation 91 (1995) 2717-2720
6. Zafeiridis A., Jeevanandam V., Houser S.R., and Margulies K.B. Regression of cellular hypertrophy after left ventricular assist device support. Circulation 98 (1998) 656-662
7. 2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circ Res 91 (2002) 517-524
8. Heerdt P.M., Holmes J.W., Cai B., et al. Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in endstage heart failure. Circulation 102 (2000) 2713-2719
9. Dipla K., Mattiello J.A., Jeevanandam V., Houser S.R., and Margulies K.B. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation 97 (1998) 2316-2322
10. Margulies K.B., Matiwala S., Cornejo C., Olsen H., Craven W.A., and Bednarik D. Mixed messages transcription patterns in failing and recovering human myocardium. Circ Res 96 (2005) 592-599
11. Torre-Amione G., Stetson S.J., Youker K.A., et al. Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support: a potential mechanism for cardiac recovery. Circulation 100 (1999) 1189-1193
12. Wolff M.R., Buck S.H., Stoker S.W., Greaser M.L., and Mentzer R.M. Myofibrillar calcium sensitivity of isometric tension is increased in human dilated cardiomyopathies: role of altered beta adrenergically mediated protein phosphorylation. J Clin Invest 98 (1996) 167-176
13. Mancini D.M., Beniaminovitz A., Levin H., et al. Low incidence of myocardial recovery after left ventricular assist device implantation in patients with chronic heart failure. Circulation 98 (1998) 2383-2389
14. Helman D.N., Maybaum S.W., Morales D.L.S., et al. Recurrent remodeling after ventricular assistance: is long-term myocardial recovery attainable?. Ann Thorac Surg 70 (2000) 1255-1258
15. Hon K.F.J., and Yacoub M.H. Bridge to recovery with the use of left ventricular assist device and clenbuterol. Ann Thorac Surg 75 suppl (2003) S36-S41
16. Yacoub M. A novel strategy to maximize the efficacy of left ventricular assist devices as a bridge to recovery. Eur Heart J 22 (2001) 534-540
17. Reinlib L., and Abraham W. Recovery from heart failure with circulatory assist: a working group of the National Heart, Lung and Blood Institute. J Card Fail 9 (2003) 459-463
18. Ferrari M., Kadipasaoglu K.A., Croitoru M., et al. Evaluation of myocardial function in patients with end-stage heart failure during support with the Jarvik 2000 left ventricular assist device. J Heart Lung Transplant 24 (2005) 226-228
19. Gorcsan III J., Severyn D., Murali S., and Kormos R.L. Non-invasive assessment of myocardial recovery on chronic left ventricular assist device: results associated with successful device removal. J Heart Lung Transplant 22 (2003) 1304-1313
20. Khan T., Delgado R.M., Radovancevic B., et al. Dobutamine stress echocardiography predicts myocardial improvement in patients supported by left ventricular assist devices (LVADs): hemodynamic and histologic evidence of improvement before LVAD explantation. J Heart Lung Transplant 22 (2003) 137-146
21. Hetzer R., Muller J.H., Weng Y., Meyer R., and Dandel M. Bridging-to-recovery. Ann Thorac Surg 71 suppl (2001) S109-S113
22. Slaughter M.S., Silver M.A., Farrar D.J., et al. A new method of monitoring recovery and weaning the Thoratec left ventricular assist device. Ann Thorac Surg 71 (2001) 215-218
23. McConnell P.I., and Sun B.C. Pressure-volume analysis during axial flow VAD support. J Heart Lung Transplant 25 (2005) 256-257
24. Sakamoto T. Evaluation of native left ventricular function during mechanical circulatory support: theoretical basis and clinical limitations. Ann Thorac Cardiovasc Surg 8 (2002) 1-6
25. Sagawa K. The end-systolic pressure-volume relation of the ventricle: definition, modifications and clinical use. Circulation 63 (1981) 1223-1227
26. Glower D.D., Spratt J.A., Snow I.D., et al. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation 71 (1985) 994-1009
27. Krukenkamp I.B., Silverman N.A., Kollmorgen T.A., and Levitsky S. Correlation between the linearized Frank-Starling relationship and myocardial energetics in the ejecting heart: effect of protected and unprotected global ischemia. J Thorac Cardiovasc Surg 95 (1988) 455-464
28. Takaoka H., Suga H., Goto Y., Hata K., and Takeuchi M. Cardiodynamic conditions for the linearity of the preload recruitable stroke work. Heart Vessels 10 (1995) 57-68
29. Little W.C., Cheng C.P., Peterson T., and Vinten-Johansen J. Response of the left ventricular end-systolic pressure volume relation in conscious dogs to a wide range of contractile states. Circulation 78 (1988) 736-745
30. Goldstein A.H., Monreal G., Kambara A., et al. Partial support with a centrifugal left ventricular assist device reduces myocardial oxygen consumption in chronic, ischemic heart failure. J Card Fail 11 (2005) 142-151
31. Sarnoff S.J., and Berglund E. Ventricular function I. Starling's law of the heart studied by means of simultaneous right and left ventricular function curves in the dog. Circulation 9 (1954) 706-718
32. Olsen C.O., Tyson G.S., Maier G.W., Spratt J.A., Davis J.W., and Rankin J.S. Dynamic ventricular interaction in the conscious dog. Circ Res 52 (1983) 85
33. Tyson G.S., Maier G.W., Olsen C.O., Davis J.W., and Rankin J.S. Pericardial influences on ventricular filling in the conscious dog: an analysis based on pericardial pressure. Circ Res 54 (1984) 173
34. Hajdu M.A., Cornish K.G., Pazenbeck M.J., and Zucker I.H. The interaction of the Bainbridge and Bezold-Jarish reflexes in the conscious dog. Basic Res Cardiol 86 (1991) 175-185